3-ISOPROPYLMALDEHYDROG-RXN

Reaction 3-ISOPROPYLMALDEHYDROG-RXN

• common-name:
  • 3-isopropylmalate dehydrogenase
• direction:
  • reversible
• synonymous:
  • β-isopropylmalic enzyme
  • threo-ds-3-isopropylmalate dehydrogenase

Reaction formula

• 1 2-D-THREO-HYDROXY-3-CARBOXY-ISOCAPROATE[c] + 1 NAD[c] <=> 1 CPD-7100[c] + 1 NADH[c] + 1 PROTON[c]

Gene(s) associated with this reaction

• Gene: g4330.t1
  • Category: annotation
    • Source: cladosiphon_okamuranus, Tool: pathwaytools, Assignment: ec-number, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_arabidopsis_thaliana, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a

Pathway(s)

• LEUSYN-PWY, L-leucine biosynthesis:
  • 5 reactions found over 6 reactions in the full pathway
• PWY-6871, 3-methylbutanol biosynthesis (engineered):
  • 5 reactions found over 7 reactions in the full pathway

Reconstruction information

• category: orthology; source: output_pantograph_ectocarpus_siliculosus; tool: pantograph; comment: n.a
• category: orthology; source: output_pantograph_saccharina_japonica; tool: pantograph; comment: n.a
• category: orthology; source: output_pantograph_arabidopsis_thaliana; tool: pantograph; comment: n.a
• category: annotation; source: cladosiphon_okamuranus; tool: pathwaytools; comment: n.a

External links

• METANETX-RXN : MNXR100878
• RHEA:
  • 10895
• LIGAND-RXN:
  • R04426
• UNIPROT:
  • P05644
  • P05645
  • Q01987
  • Q00412
  • P08791
  • P30125
  • Q9PLW0
  • O66607
  • P12010
  • P04173
  • Q5SIY4
  • P24098
  • Q9JU79
  • P43860
  • P41019
  • P54354
  • Q56268
  • P29102
  • P37412
  • P23390
  • P29696
  • P41766
  • Q02143
  • P34733
  • P50180
  • Q12591
  • Q12590
  • Q12592
  • P07139
  • P41926
  • P48012
  • P87256
  • P87257
  • P73960
  • O86504
  • O85837
  • P18869
  • P34738