RXN3O-130

Reaction RXN3O-130

• common-name:
  • sterol 14-demethylase
• direction:
  • left-to-right
• ec-number:
  • ec-1.14.13.70

Reaction formula

• 1 LANOSTEROL[c] + 3 NADPH[c] + 3 OXYGEN-MOLECULE[c] + 2 PROTON[c] => 1 44-DIMETHYL-CHOLESTA-814-24-TRIENOL[c] + 1 FORMATE[c] + 3 NADP[c] + 4 WATER[c]

Gene(s) associated with this reaction

• Gene: g18563.t1
  • Category: annotation
    • Source: cladosiphon_okamuranus, Tool: pathwaytools, Assignment: go-term, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: g13113.t1
  • Category: annotation
    • Source: cladosiphon_okamuranus, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: g12684.t1
  • Category: annotation
    • Source: cladosiphon_okamuranus, Tool: pathwaytools, Assignment: go-term, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: g12685.t1
  • Category: annotation
    • Source: cladosiphon_okamuranus, Tool: pathwaytools, Assignment: go-term, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: g14468.t1
  • Category: annotation
    • Source: cladosiphon_okamuranus, Tool: pathwaytools, Assignment: go-term, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: g12687.t1
  • Category: annotation
    • Source: cladosiphon_okamuranus, Tool: pathwaytools, Assignment: go-term, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: g4142.t1
  • Category: annotation
    • Source: cladosiphon_okamuranus, Tool: pathwaytools, Assignment: go-term, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: g12686.t1
  • Category: annotation
    • Source: cladosiphon_okamuranus, Tool: pathwaytools, Assignment: go-term, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: g11283.t1
  • Category: annotation
    • Source: cladosiphon_okamuranus, Tool: pathwaytools, Assignment: go-term, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: g4115.t1
  • Category: annotation
    • Source: cladosiphon_okamuranus, Tool: pathwaytools, Assignment: go-term, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: g14467.t1
  • Category: annotation
    • Source: cladosiphon_okamuranus, Tool: pathwaytools, Assignment: go-term, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a

Pathway(s)

• PWY-6074, zymosterol biosynthesis:
  • 6 reactions found over 14 reactions in the full pathway

Reconstruction information

• category: annotation; source: cladosiphon_okamuranus; tool: pathwaytools; comment: n.a
• category: orthology; source: output_pantograph_ectocarpus_siliculosus; tool: pantograph; comment: n.a
• category: orthology; source: output_pantograph_saccharina_japonica; tool: pantograph; comment: n.a

External links

• METANETX-RXN : MNXR109729
• RHEA:
  • 25287
• LIGAND-RXN:
  • R05640