ACETOOHBUTSYN-RXN

Reaction ACETOOHBUTSYN-RXN

• direction:
  • left-to-right
• common-name:
  • 2-aceto-2-hydroxy-butyrate synthase
  • acetolactate synthase small subunit
  • acetolactate synthase, large subunit, biosynthetic type
• ec-number:
  • ec-2.2.1.6

Reaction formula

• 1 2-OXOBUTANOATE[c] + 1 PROTON[c] + 1 PYRUVATE[c] => 1 2-ACETO-2-HYDROXY-BUTYRATE[c] + 1 CARBON-DIOXIDE[c]

Gene(s) associated with this reaction

• Gene: RUMFLAFD1_RS0119590
  • Category: annotation
    • Source: genome_a, Tool: pathwaytools, Assignment: automated-name-match, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_faecalibacteriumprausnitziia2-165_heinken2014, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_bifidobacteriumadolescentisl2-32, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_bthetaiotaomicron_heinken2013, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: RUMFLAFD1_RS0119595
  • Category: annotation
    • Source: genome_a, Tool: pathwaytools, Assignment: automated-name-match, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_faecalibacteriumprausnitziia2-165_heinken2014, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_bifidobacteriumadolescentisl2-32, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_bthetaiotaomicron_heinken2013, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_l_plantarum_wcfs1, Tool: pantograph, Assignment: n.a, Comment: n.a

Pathway(s)

• PWY-5104, L-isoleucine biosynthesis IV:
  • 3 reactions found over 6 reactions in the full pathway
• PWY-5101, L-isoleucine biosynthesis II:
  • 3 reactions found over 8 reactions in the full pathway
• PWY-5103, L-isoleucine biosynthesis III:
  • 4 reactions found over 7 reactions in the full pathway
• ILEUSYN-PWY, L-isoleucine biosynthesis I (from threonine):
  • 7 reactions found over 7 reactions in the full pathway

Reconstruction information

• category: orthology; source: output_pantograph_bthetaiotaomicron_heinken2013; tool: pantograph; comment: n.a
• category: orthology; source: output_pantograph_bifidobacteriumadolescentisl2-32; tool: pantograph; comment: n.a
• category: orthology; source: output_pantograph_l_plantarum_wcfs1; tool: pantograph; comment: n.a
• category: annotation; source: genome_a; tool: pathwaytools; comment: n.a
• category: orthology; source: output_pantograph_faecalibacteriumprausnitziia2-165_heinken2014; tool: pantograph; comment: n.a

External links

• RHEA:
  • 27655
• LIGAND-RXN:
  • R08648
• UNIPROT:
  • Q59950
  • P42463
  • Q8XAV3
  • P27868
  • P45260
  • Q57625
  • P37251
  • P45261
  • O27493
  • O66759
  • Q9PHU2
  • O05031
  • Q57725
  • Q9PHU1
  • Q9JTI1
  • Q58077
  • O28554
  • O53554
  • Q04789
  • Q9JRF4
  • Q59272
  • P27696
  • Q59498
  • Q9RFQ7
  • Q05767
  • P40811
  • P21622
  • P27818
  • Q41768
  • Q41769
  • P69684
  • P27819
  • Q9R586
  • Q02137
  • Q02140
  • P36620
  • Q42767
  • Q42768
  • Q49865
  • O22547
  • O49229
  • O22578
  • O49210
  • Q60021
  • P07342
  • P00892
  • P08142
  • P0ADF8
  • P00894
  • P00893
  • P17597
  • P09342
  • P09114
  • P14874