Difference between revisions of "PORPHOBILSYNTH-RXN"

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(Created page with "Category:reaction == Reaction RXN1G-2527 == * common-name: ** cis,cis-δ19-37-c56:2-[acp] methyltransferase-hydroxylase ** enoyl-[acyl-carrier-protein] reductase * ec...")
(Created page with "Category:reaction == Reaction PORPHOBILSYNTH-RXN == * common-name: ** porphobilinogen synthase * ec-number: ** [http://enzyme.expasy.org/EC/4.2.1.24 ec-4.2.1.24] * directi...")
 
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[[Category:reaction]]
 
[[Category:reaction]]
−
== Reaction RXN1G-2527 ==
+
== Reaction PORPHOBILSYNTH-RXN ==
 
* common-name:
 
* common-name:
−
** cis,cis-δ19-37-c56:2-[acp] methyltransferase-hydroxylase
+
** porphobilinogen synthase
−
** enoyl-[acyl-carrier-protein] reductase
 
 
* ec-number:
 
* ec-number:
−
** [http://enzyme.expasy.org/EC/2.1.1 ec-2.1.1]
+
** [http://enzyme.expasy.org/EC/4.2.1.24 ec-4.2.1.24]
 
* direction:
 
* direction:
 
** left-to-right
 
** left-to-right
 
== Reaction formula ==
 
== Reaction formula ==
−
* 1 [[S-ADENOSYLMETHIONINE]][c] '''+''' 1 [[WATER]][c] '''+''' 1 [[cis-cis-D19-37-C56-2-ACPs]][c] '''=>''' 1 [[ADENOSYL-HOMO-CYS]][c] '''+''' 1 [[PROTON]][c] '''+''' 1 [[cis-D19-37-OH-38-Me-C57-1-ACPs]][c]
+
* 2 [[5-AMINO-LEVULINATE]][c] '''=>''' 1 [[PORPHOBILINOGEN]][c] '''+''' 1 [[PROTON]][c] '''+''' 2 [[WATER]][c]
 
== Gene(s) associated with this reaction  ==
 
== Gene(s) associated with this reaction  ==
−
* Gene: [[E_subulatus_16468]]
+
* Gene: [[E_subulatus_07842]]
 
** Category: [[annotation]]
 
** Category: [[annotation]]
−
*** Source: [[ectocarpus_subulatus]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
+
*** Source: [[ectocarpus_subulatus]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
−
* Gene: [[E_subulatus_16466]]
+
** Category: [[orthology]]
−
** Category: [[annotation]]
+
*** Source: [[output_pantograph_a.taliana.aragem]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
−
*** Source: [[ectocarpus_subulatus]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[E_subulatus_24601]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[ectocarpus_subulatus]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[E_subulatus_16469]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[ectocarpus_subulatus]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[E_subulatus_16467]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[ectocarpus_subulatus]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
 
== Pathway(s)  ==
 
== Pathway(s)  ==
−
* [[PWYG-321]], mycolate biosynthesis:
+
* [[PWY-5188]], tetrapyrrole biosynthesis I (from glutamate):
−
** '''43''' reactions found over '''205''' reactions in the full pathway
+
** '''6''' reactions found over '''6''' reactions in the full pathway
 +
* [[PWY-5189]], tetrapyrrole biosynthesis II (from glycine):
 +
** '''3''' reactions found over '''4''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 
* category: [[annotation]]; source: [[ectocarpus_subulatus]]; tool: [[pathwaytools]]; comment: n.a
 
* category: [[annotation]]; source: [[ectocarpus_subulatus]]; tool: [[pathwaytools]]; comment: n.a
 +
* category: [[orthology]]; source: [[output_pantograph_a.taliana.aragem]]; tool: [[pantograph]]; comment: n.a
 
== External links  ==
 
== External links  ==
−
* METANETX-RXN : MNXR123513
+
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
−
{{#set: common-name=cis,cis-&delta;19-37-c56:2-[acp] methyltransferase-hydroxylase|enoyl-[acyl-carrier-protein] reductase}}
+
* METANETX-RXN : MNXR103095
−
{{#set: ec-number=ec-2.1.1}}
+
* RHEA:
 +
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=24064 24064]
 +
* LIGAND-RXN:
 +
** [http://www.genome.jp/dbget-bin/www_bget?R00036 R00036]
 +
* UNIPROT:
 +
** [http://www.uniprot.org/uniprot/P06214 P06214]
 +
** [http://www.uniprot.org/uniprot/P13716 P13716]
 +
** [http://www.uniprot.org/uniprot/Q7M315 Q7M315]
 +
** [http://www.uniprot.org/uniprot/P30124 P30124]
 +
** [http://www.uniprot.org/uniprot/Q9JV37 Q9JV37]
 +
** [http://www.uniprot.org/uniprot/P30950 P30950]
 +
** [http://www.uniprot.org/uniprot/Q60178 Q60178]
 +
** [http://www.uniprot.org/uniprot/Q9PNU5 Q9PNU5]
 +
** [http://www.uniprot.org/uniprot/Q59295 Q59295]
 +
** [http://www.uniprot.org/uniprot/Q02250 Q02250]
 +
** [http://www.uniprot.org/uniprot/P10518 P10518]
 +
** [http://www.uniprot.org/uniprot/Q43148 Q43148]
 +
** [http://www.uniprot.org/uniprot/Q42682 Q42682]
 +
** [http://www.uniprot.org/uniprot/Q43058 Q43058]
 +
** [http://www.uniprot.org/uniprot/Q59643 Q59643]
 +
** [http://www.uniprot.org/uniprot/Q9S8B1 Q9S8B1]
 +
** [http://www.uniprot.org/uniprot/P05373 P05373]
 +
** [http://www.uniprot.org/uniprot/P0ACB2 P0ACB2]
 +
** [http://www.uniprot.org/uniprot/Q42836 Q42836]
 +
** [http://www.uniprot.org/uniprot/P43210 P43210]
 +
** [http://www.uniprot.org/uniprot/Q9ZNC9 Q9ZNC9]
 +
</div>
 +
{{#set: common-name=porphobilinogen synthase}}
 +
{{#set: ec-number=ec-4.2.1.24}}
 
{{#set: direction=left-to-right}}
 
{{#set: direction=left-to-right}}
−
{{#set: nb gene associated=5}}
+
{{#set: nb gene associated=1}}
−
{{#set: nb pathway associated=1}}
+
{{#set: nb pathway associated=2}}
−
{{#set: reconstruction category=annotation}}
+
{{#set: reconstruction category=annotation|orthology}}
−
{{#set: reconstruction tool=pathwaytools}}
+
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
{{#set: reconstruction comment=n.a}}
 
{{#set: reconstruction comment=n.a}}
−
{{#set: reconstruction source=ectocarpus_subulatus}}
+
{{#set: reconstruction source=output_pantograph_a.taliana.aragem|ectocarpus_subulatus}}

Latest revision as of 19:39, 17 March 2021

Reaction PORPHOBILSYNTH-RXN

  • common-name:
    • porphobilinogen synthase
  • ec-number:
  • direction:
    • left-to-right

Reaction formula

Gene(s) associated with this reaction

Pathway(s)

  • PWY-5188, tetrapyrrole biosynthesis I (from glutamate):
    • 6 reactions found over 6 reactions in the full pathway
  • PWY-5189, tetrapyrrole biosynthesis II (from glycine):
    • 3 reactions found over 4 reactions in the full pathway

Reconstruction information

External links





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