Difference between revisions of "2-ISOPROPYLMALATESYN-RXN"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=R222-RXN R222-RXN] == * common name: ** 1-octanal dehydrogenase (NAD+) ** 4-trimethylaminobutyralde...")
 
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=2-ISOPROPYLMALATESYN-RXN 2-ISOPROPYLMALATESYN-RXN] == * common name: ** 2-isopropylmalate synthase...")
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
−
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=R222-RXN R222-RXN] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=2-ISOPROPYLMALATESYN-RXN 2-ISOPROPYLMALATESYN-RXN] ==
 
* common name:
 
* common name:
−
** 1-octanal dehydrogenase (NAD+)
+
** 2-isopropylmalate synthase
−
** 4-trimethylaminobutyraldehyde dehydrogenase
 
 
* ec number:
 
* ec number:
−
** [http://enzyme.expasy.org/EC/1.2.1.3 EC-1.2.1.3]
+
** [http://enzyme.expasy.org/EC/2.3.3.13 EC-2.3.3.13]
 
* direction:
 
* direction:
 
** LEFT-TO-RIGHT
 
** LEFT-TO-RIGHT
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== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1 [[CPD-371]][c] '''+''' 1 [[NAD]][c] '''+''' 1 [[WATER]][c] '''=>''' 1 [[NADH]][c] '''+''' 1 [[CPD-195]][c] '''+''' 2 [[PROTON]][c]
+
** 1 [[ACETYL-COA]][c] '''+''' 1 [[2-KETO-ISOVALERATE]][c] '''+''' 1 [[WATER]][c] '''=>''' 1 [[PROTON]][c] '''+''' 1 [[3-CARBOXY-3-HYDROXY-ISOCAPROATE]][c] '''+''' 1 [[CO-A]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1 1-octanal[c] '''+''' 1 NAD+[c] '''+''' 1 H2O[c] '''=>''' 1 NADH[c] '''+''' 1 octanoate[c] '''+''' 2 H+[c]
+
** 1 acetyl-CoA[c] '''+''' 1 3-methyl-2-oxobutanoate[c] '''+''' 1 H2O[c] '''=>''' 1 H+[c] '''+''' 1 (2S)-2-isopropylmalate[c] '''+''' 1 coenzyme A[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
−
* Gene: [[DN7759_c0_g1_i1]]
+
* Gene: [[DN33254_c0_g1_i1]]
 
** Source: [[annotation-transcriptome]]
 
** Source: [[annotation-transcriptome]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
 
== Pathways  ==
 
== Pathways  ==
−
* [[P221-PWY]], octane oxidation: [http://metacyc.org/META/NEW-IMAGE?object=P221-PWY P221-PWY]
+
* [[PWY-6871]], 3-methylbutanol biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6871 PWY-6871]
−
** '''1''' reactions found over '''NA''' reactions in the full pathway
+
** '''4''' reactions found over '''NA''' reactions in the full pathway
 +
* [[LEUSYN-PWY]], L-leucine biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=LEUSYN-PWY LEUSYN-PWY]
 +
** '''5''' reactions found over '''NA''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 
* Category: [[annotation]]
 
* Category: [[annotation]]
Line 29: Line 30:
 
*** Tool: [[pathwaytools]]
 
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
−
{{#set: common name=1-octanal dehydrogenase (NAD+)}}
+
* RHEA:
−
{{#set: common name=4-trimethylaminobutyraldehyde dehydrogenase}}
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=21525 21525]
−
{{#set: ec number=EC-1.2.1.3}}
+
* LIGAND-RXN:
 +
** [http://www.genome.jp/dbget-bin/www_bget?R01213 R01213]
 +
* UNIPROT:
 +
** [http://www.uniprot.org/uniprot/P06208 P06208]
 +
** [http://www.uniprot.org/uniprot/Q58595 Q58595]
 +
** [http://www.uniprot.org/uniprot/P09151 P09151]
 +
** [http://www.uniprot.org/uniprot/Q9PLV9 Q9PLV9]
 +
** [http://www.uniprot.org/uniprot/Q9JUK6 Q9JUK6]
 +
** [http://www.uniprot.org/uniprot/Q58787 Q58787]
 +
** [http://www.uniprot.org/uniprot/P94565 P94565]
 +
** [http://www.uniprot.org/uniprot/Q9JP75 Q9JP75]
 +
** [http://www.uniprot.org/uniprot/Q02141 Q02141]
 +
** [http://www.uniprot.org/uniprot/P48575 P48575]
 +
** [http://www.uniprot.org/uniprot/O86511 O86511]
 +
{{#set: common name=2-isopropylmalate synthase}}
 +
{{#set: ec number=EC-2.3.3.13}}
 
{{#set: direction=LEFT-TO-RIGHT}}
 
{{#set: direction=LEFT-TO-RIGHT}}
−
{{#set: gene associated=DN7759_c0_g1_i1}}
+
{{#set: gene associated=DN33254_c0_g1_i1}}
−
{{#set: in pathway=P221-PWY}}
+
{{#set: in pathway=PWY-6871|LEUSYN-PWY}}
 
{{#set: reconstruction category=annotation}}
 
{{#set: reconstruction category=annotation}}
 
{{#set: reconstruction source=annotation-transcriptome}}
 
{{#set: reconstruction source=annotation-transcriptome}}
 
{{#set: reconstruction tool=pathwaytools}}
 
{{#set: reconstruction tool=pathwaytools}}

Latest revision as of 14:21, 15 January 2021

Reaction 2-ISOPROPYLMALATESYN-RXN

  • common name:
    • 2-isopropylmalate synthase
  • ec number:
  • direction:
    • LEFT-TO-RIGHT
  • Synonym(s):

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-6871, 3-methylbutanol biosynthesis (engineered): PWY-6871
    • 4 reactions found over NA reactions in the full pathway
  • LEUSYN-PWY, L-leucine biosynthesis: LEUSYN-PWY
    • 5 reactions found over NA reactions in the full pathway

Reconstruction information

External links





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