Difference between revisions of "R-2-METHYLMALATE-DEHYDRATASE-RXN"

From metabolic_network
Jump to navigation Jump to search
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=METHENYLTHFCYCLOHYDRO-RXN METHENYLTHFCYCLOHYDRO-RXN] == * common name: ** methenyltetrahydrofolate...")
 
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=R-2-METHYLMALATE-DEHYDRATASE-RXN R-2-METHYLMALATE-DEHYDRATASE-RXN] == * common name: ** (R)-2-methy...")
 
Line 1: Line 1:
 
[[Category:Reaction]]
 
[[Category:Reaction]]
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=METHENYLTHFCYCLOHYDRO-RXN METHENYLTHFCYCLOHYDRO-RXN] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=R-2-METHYLMALATE-DEHYDRATASE-RXN R-2-METHYLMALATE-DEHYDRATASE-RXN] ==
 
* common name:
 
* common name:
** methenyltetrahydrofolate cyclohydrolase
+
** (R)-2-methylmalate hydro-lyase (2-methylmaleate-forming)
 
* ec number:
 
* ec number:
** [http://enzyme.expasy.org/EC/3.5.4.9 EC-3.5.4.9]
+
** [http://enzyme.expasy.org/EC/4.2.1.35 EC-4.2.1.35]
 
* direction:
 
* direction:
 
** REVERSIBLE
 
** REVERSIBLE
Line 11: Line 11:
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
** 1 [[5-10-METHENYL-THF-GLU-N]][c] '''+''' 1 [[WATER]][c] '''<=>''' 1 [[FORMYL-THF-GLU-N]][c] '''+''' 1 [[PROTON]][c]
+
** 1 [[CPD-31]][c] '''<=>''' 1 [[2-METHYLMALEATE]][c] '''+''' 1 [[WATER]][c]
 
* With common name(s):
 
* With common name(s):
** 1 a 5,10-methenyltetrahydrofolate[c] '''+''' 1 H2O[c] '''<=>''' 1 an N10-formyl-tetrahydrofolate[c] '''+''' 1 H+[c]
+
** 1 (R)-citramalate[c] '''<=>''' 1 citraconate[c] '''+''' 1 H2O[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
* Gene: [[DN14675_c0_g1_i2]]
+
* Gene: [[DN18105_c0_g1_i1]]
** Source: [[annotation-transcriptome]]
 
*** Assignment: EC-NUMBER
 
* Gene: [[DN22211_c0_g1_i3]]
 
** Source: [[annotation-transcriptome]]
 
*** Assignment: EC-NUMBER
 
* Gene: [[DN22211_c0_g1_i1]]
 
** Source: [[annotation-transcriptome]]
 
*** Assignment: EC-NUMBER
 
* Gene: [[DN22211_c0_g1_i4]]
 
** Source: [[annotation-transcriptome]]
 
*** Assignment: EC-NUMBER
 
* Gene: [[DN19349_c0_g1_i2]]
 
** Source: [[annotation-transcriptome]]
 
*** Assignment: EC-NUMBER
 
* Gene: [[DN14675_c0_g1_i1]]
 
 
** Source: [[annotation-transcriptome]]
 
** Source: [[annotation-transcriptome]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
 
== Pathways  ==
 
== Pathways  ==
* [[PWY-3841]], folate transformations II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-3841 PWY-3841]
+
* [[PWY-5101]], L-isoleucine biosynthesis II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5101 PWY-5101]
** '''7''' reactions found over '''NA''' reactions in the full pathway
 
* [[PWY-2201]], folate transformations I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-2201 PWY-2201]
 
** '''5''' reactions found over '''NA''' reactions in the full pathway
 
* [[CODH-PWY]], reductive acetyl coenzyme A pathway I (homoacetogenic bacteria): [http://metacyc.org/META/NEW-IMAGE?object=CODH-PWY CODH-PWY]
 
** '''3''' reactions found over '''NA''' reactions in the full pathway
 
* [[1CMET2-PWY]], N10-formyl-tetrahydrofolate biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=1CMET2-PWY 1CMET2-PWY]
 
** '''6''' reactions found over '''NA''' reactions in the full pathway
 
* [[PWY-6613]], tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6613 PWY-6613]
 
** '''2''' reactions found over '''NA''' reactions in the full pathway
 
* [[PWY-5497]], purine nucleobases degradation II (anaerobic): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5497 PWY-5497]
 
 
** '''4''' reactions found over '''NA''' reactions in the full pathway
 
** '''4''' reactions found over '''NA''' reactions in the full pathway
* [[P164-PWY]], purine nucleobases degradation I (anaerobic): [http://metacyc.org/META/NEW-IMAGE?object=P164-PWY P164-PWY]
+
* [[PWY-7698]], 2,5-xylenol and 3,5-xylenol degradation: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7698 PWY-7698]
** '''3''' reactions found over '''NA''' reactions in the full pathway
 
* [[PWY-5030]], L-histidine degradation III: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5030 PWY-5030]
 
 
** '''1''' reactions found over '''NA''' reactions in the full pathway
 
** '''1''' reactions found over '''NA''' reactions in the full pathway
* [[PWY-7909]], formaldehyde oxidation VII (THF pathway): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7909 PWY-7909]
 
** '''2''' reactions found over '''NA''' reactions in the full pathway
 
* [[PWY-1722]], formate assimilation into 5,10-methylenetetrahydrofolate: [http://metacyc.org/META/NEW-IMAGE?object=PWY-1722 PWY-1722]
 
** '''3''' reactions found over '''NA''' reactions in the full pathway
 
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 
* Category: [[annotation]]
 
* Category: [[annotation]]
Line 62: Line 31:
 
== External links  ==
 
== External links  ==
 
* RHEA:
 
* RHEA:
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=23703 23703]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=22332 22332]
 
* LIGAND-RXN:
 
* LIGAND-RXN:
** [http://www.genome.jp/dbget-bin/www_bget?R01655 R01655]
+
** [http://www.genome.jp/dbget-bin/www_bget?R03896 R03896]
* UNIPROT:
+
{{#set: common name=(R)-2-methylmalate hydro-lyase (2-methylmaleate-forming)}}
** [http://www.uniprot.org/uniprot/P09440 P09440]
+
{{#set: ec number=EC-4.2.1.35}}
** [http://www.uniprot.org/uniprot/P07245 P07245]
 
** [http://www.uniprot.org/uniprot/P11586 P11586]
 
** [http://www.uniprot.org/uniprot/P18155 P18155]
 
** [http://www.uniprot.org/uniprot/P44313 P44313]
 
** [http://www.uniprot.org/uniprot/P47259 P47259]
 
** [http://www.uniprot.org/uniprot/P13995 P13995]
 
** [http://www.uniprot.org/uniprot/P54382 P54382]
 
** [http://www.uniprot.org/uniprot/O67736 O67736]
 
** [http://www.uniprot.org/uniprot/Q9JWI9 Q9JWI9]
 
** [http://www.uniprot.org/uniprot/Q9PP68 Q9PP68]
 
** [http://www.uniprot.org/uniprot/P24186 P24186]
 
** [http://www.uniprot.org/uniprot/Q04448 Q04448]
 
** [http://www.uniprot.org/uniprot/Q60006 Q60006]
 
** [http://www.uniprot.org/uniprot/Q27772 Q27772]
 
** [http://www.uniprot.org/uniprot/P51696 P51696]
 
** [http://www.uniprot.org/uniprot/O68031 O68031]
 
** [http://www.uniprot.org/uniprot/Q9ZTV0 Q9ZTV0]
 
** [http://www.uniprot.org/uniprot/Q9X7F6 Q9X7F6]
 
{{#set: common name=methenyltetrahydrofolate cyclohydrolase}}
 
{{#set: ec number=EC-3.5.4.9}}
 
 
{{#set: direction=REVERSIBLE}}
 
{{#set: direction=REVERSIBLE}}
{{#set: gene associated=DN14675_c0_g1_i2|DN22211_c0_g1_i3|DN22211_c0_g1_i1|DN22211_c0_g1_i4|DN19349_c0_g1_i2|DN14675_c0_g1_i1}}
+
{{#set: gene associated=DN18105_c0_g1_i1}}
{{#set: in pathway=PWY-3841|PWY-2201|CODH-PWY|1CMET2-PWY|PWY-6613|PWY-5497|P164-PWY|PWY-5030|PWY-7909|PWY-1722}}
+
{{#set: in pathway=PWY-5101|PWY-7698}}
 
{{#set: reconstruction category=annotation}}
 
{{#set: reconstruction category=annotation}}
 
{{#set: reconstruction source=annotation-transcriptome}}
 
{{#set: reconstruction source=annotation-transcriptome}}
 
{{#set: reconstruction tool=pathwaytools}}
 
{{#set: reconstruction tool=pathwaytools}}

Latest revision as of 14:21, 15 January 2021

Reaction R-2-METHYLMALATE-DEHYDRATASE-RXN

  • common name:
    • (R)-2-methylmalate hydro-lyase (2-methylmaleate-forming)
  • ec number:
  • direction:
    • REVERSIBLE
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 (R)-citramalate[c] <=> 1 citraconate[c] + 1 H2O[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-5101, L-isoleucine biosynthesis II: PWY-5101
    • 4 reactions found over NA reactions in the full pathway
  • PWY-7698, 2,5-xylenol and 3,5-xylenol degradation: PWY-7698
    • 1 reactions found over NA reactions in the full pathway

Reconstruction information

External links