QUINOPRIBOTRANS-RXN

Reaction QUINOPRIBOTRANS-RXN

• common-name:
  • nicotinate-nucleotide diphosphorylase (carboxylating)
  • quinolinate phosphoribosyltransferase (decarboxylating)
• direction:
  • left-to-right
• ec-number:
  • ec-2.4.2.19

Reaction formula

• 2 PROTON[c] + 1 PRPP[c] + 1 QUINOLINATE[c] => 1 CARBON-DIOXIDE[c] + 1 NICOTINATE_NUCLEOTIDE[c] + 1 PPI[c]

Gene(s) associated with this reaction

• Gene: g6645.t1
  • Category: annotation
    • Source: cladosiphon_okamuranus, Tool: pathwaytools, Assignment: go-term, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: g3741.t1
  • Category: orthology
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: g17229.t1
  • Category: orthology
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: g17694.t1
  • Category: orthology
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: g8192.t1
  • Category: annotation
    • Source: cladosiphon_okamuranus, Tool: pathwaytools, Assignment: ec-number, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_nannochloropsis_salina, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_nannochloropsis_salina, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_arabidopsis_thaliana, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: g9429.t1
  • Category: annotation
    • Source: cladosiphon_okamuranus, Tool: pathwaytools, Assignment: go-term, Comment: n.a

Pathway(s)

• PWY-5316, nicotine biosynthesis:
  • 3 reactions found over 9 reactions in the full pathway
• PWY-5653, NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde:
  • 3 reactions found over 4 reactions in the full pathway
• PWY-7342, superpathway of nicotine biosynthesis:
  • 4 reactions found over 9 reactions in the full pathway
• PYRIDNUCSYN-PWY, NAD de novo biosynthesis I (from aspartate):
  • 6 reactions found over 6 reactions in the full pathway

Reconstruction information

• category: orthology; source: output_pantograph_arabidopsis_thaliana; tool: pantograph; comment: n.a
• category: orthology; source: output_pantograph_nannochloropsis_salina; tool: pantograph; comment: n.a
• category: orthology; source: output_pantograph_ectocarpus_siliculosus; tool: pantograph; comment: n.a
• category: orthology; source: output_pantograph_saccharina_japonica; tool: pantograph; comment: n.a
• category: annotation; source: cladosiphon_okamuranus; tool: pathwaytools; comment: n.a

External links

• METANETX-RXN : MNXR101980
• RHEA:
  • 12735
• LIGAND-RXN:
  • R03348
• UNIPROT:
  • Q9JSX8
  • Q57916
  • P30011
  • P46714
  • Q15274
  • P77938