RXN0-1133

Reaction RXN0-1133

• common-name:
  • lipoate acetyltransferase
  • pyruvate dehydrogenase (nad+)
• direction:
  • left-to-right
• ec-number:
  • ec-2.3.1.12

Reaction formula

• 1 CO-A[c] + 1 Pyruvate-dehydrogenase-acetylDHlipoyl[c] => 1 ACETYL-COA[c] + 1 Pyruvate-dehydrogenase-dihydrolipoate[c]

Gene(s) associated with this reaction

• Gene: g6561.t1
  • Category: annotation
    • Source: cladosiphon_okamuranus, Tool: pathwaytools, Assignment: go-term, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: g12674.t2
  • Category: annotation
    • Source: cladosiphon_okamuranus, Tool: pathwaytools, Assignment: ec-number, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: g11823.t1
  • Category: annotation
    • Source: cladosiphon_okamuranus, Tool: pathwaytools, Assignment: ec-number, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: g14052.t1
  • Category: annotation
    • Source: cladosiphon_okamuranus, Tool: pathwaytools, Assignment: ec-number, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: g13007.t1
  • Category: orthology
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: g12674.t1
  • Category: annotation
    • Source: cladosiphon_okamuranus, Tool: pathwaytools, Assignment: ec-number, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: g3821.t1
  • Category: annotation
    • Source: cladosiphon_okamuranus, Tool: pathwaytools, Assignment: ec-number, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a

Pathway(s)

• PYRUVDEHYD-PWY, pyruvate decarboxylation to acetyl CoA I:
  • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

• category: orthology; source: output_pantograph_ectocarpus_siliculosus; tool: pantograph; comment: n.a
• category: annotation; source: cladosiphon_okamuranus; tool: pathwaytools; comment: n.a
• category: orthology; source: output_pantograph_saccharina_japonica; tool: pantograph; comment: n.a

External links

• METANETX-RXN : MNXR123104
• LIGAND-RXN:
  • R02569
• UNIPROT:
  • Q01991
  • P12695
  • Q7M2M8
  • P10515
  • Q39082
  • Q9TRP7
  • Q7M0X6
  • Q59098
  • Q9PF09
  • P35489
  • P21883
  • Q59658
  • Q9JU07
  • Q59298
  • P45118
  • Q54102
  • P11961
  • Q59821
  • P08461
  • Q16791
  • Q41737
  • O64968
  • P10802
  • P06959