RXN-9623

Reaction RXN-9623

• common-name:
  • palmitate-coa ligase
  • long-chain fatty acid-coa ligase
• direction:
  • left-to-right
• ec-number:
  • ec-6.2.1.3

Reaction formula

• 1 ATP[c] + 1 CO-A[c] + 1 PALMITATE[c] => 1 AMP[c] + 1 PALMITYL-COA[c] + 1 PPI[c]

Gene(s) associated with this reaction

• Gene: g16417.t1
  • Category: orthology
    • Source: output_pantograph_nannochloropsis_salina, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: g16711.t1
  • Category: annotation
    • Source: cladosiphon_okamuranus, Tool: pathwaytools, Assignment: ec-number, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_arabidopsis_thaliana, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: g7072.t1
  • Category: annotation
    • Source: cladosiphon_okamuranus, Tool: pathwaytools, Assignment: go-term, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_arabidopsis_thaliana, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: g7800.t1
  • Category: annotation
    • Source: cladosiphon_okamuranus, Tool: pathwaytools, Assignment: ec-number, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_nannochloropsis_salina, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: g10473.t1
  • Category: annotation
    • Source: cladosiphon_okamuranus, Tool: pathwaytools, Assignment: ec-number, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_nannochloropsis_salina, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: g17549.t1
  • Category: annotation
    • Source: cladosiphon_okamuranus, Tool: pathwaytools, Assignment: ec-number, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_nannochloropsis_salina, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_saccharina_japonica, Tool: pantograph, Assignment: n.a, Comment: n.a

Pathway(s)

• PWY-5971, palmitate biosynthesis (type II fatty acid synthase):
  • 31 reactions found over 31 reactions in the full pathway
• PWY-5972, stearate biosynthesis I (animals):
  • 4 reactions found over 6 reactions in the full pathway

Reconstruction information

• category: orthology; source: output_pantograph_nannochloropsis_salina; tool: pantograph; comment: n.a
• category: orthology; source: output_pantograph_arabidopsis_thaliana; tool: pantograph; comment: n.a
• category: orthology; source: output_pantograph_saccharina_japonica; tool: pantograph; comment: n.a
• category: orthology; source: output_pantograph_ectocarpus_siliculosus; tool: pantograph; comment: n.a
• category: annotation; source: cladosiphon_okamuranus; tool: pathwaytools; comment: n.a

External links

• METANETX-RXN : MNXR99153
• RHEA:
  • 30754
• LIGAND-RXN:
  • R01280