ACETOOHBUTREDUCTOISOM-RXN

Reaction ACETOOHBUTREDUCTOISOM-RXN

• common-name:
  • (r)-2,3-dihydroxy-3-methylpentanoate:nadp+ oxidoreductase (isomerizing)
• ec-number:
  • ec-1.1.1.86
• direction:
  • left-to-right

Reaction formula

• 1 2-ACETO-2-HYDROXY-BUTYRATE[c] + 1 NADPH[c] + 1 PROTON[c] => 1 1-KETO-2-METHYLVALERATE[c] + 1 NADP[c]

Gene(s) associated with this reaction

• Gene: E_subulatus_11005
  • Category: annotation
    • Source: ectocarpus_subulatus, Tool: pathwaytools, Assignment: ec-number, Comment: n.a
• Gene: E_subulatus_21980
  • Category: annotation
    • Source: ectocarpus_subulatus, Tool: pathwaytools, Assignment: ec-number, Comment: n.a
• Gene: E_subulatus_18066
  • Category: annotation
    • Source: ectocarpus_subulatus, Tool: pathwaytools, Assignment: ec-number, Comment: n.a
• Gene: E_subulatus_21979
  • Category: annotation
    • Source: ectocarpus_subulatus, Tool: pathwaytools, Assignment: ec-number, Comment: n.a

Pathway(s)

• PWY-5103, L-isoleucine biosynthesis III:
  • 4 reactions found over 7 reactions in the full pathway
• ILEUSYN-PWY, L-isoleucine biosynthesis I (from threonine):
  • 7 reactions found over 7 reactions in the full pathway

Reconstruction information

• category: annotation; source: ectocarpus_subulatus; tool: pathwaytools; comment: n.a

External links

• METANETX-RXN : MNXR100902
• RHEA:
  • 13493
• UNIPROT:
  • P06168
  • P44822
  • O25097
  • Q02138
  • Q57179
  • Q9JTI3
  • Q9PHN5
  • P05793
  • P38674
  • Q59500
  • Q01292
  • Q05758
  • O82043
  • P78827