Difference between revisions of "HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN"

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(Created page with "Category:reaction == Reaction DAHPSYN-RXN == * common-name: ** 3-deoxy-7-phosphoheptulonate synthase * ec-number: ** [http://enzyme.expasy.org/EC/2.5.1.54 ec-2.5.1.54] * d...")
(Created page with "Category:reaction == Reaction HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN == * common-name: ** hydroxymethylglutaryl-coa lyase * ec-number: ** [http://enzyme.expasy.org/EC/4.1.3.4...")
 
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[[Category:reaction]]
 
[[Category:reaction]]
== Reaction DAHPSYN-RXN ==
+
== Reaction HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN ==
 
* common-name:
 
* common-name:
** 3-deoxy-7-phosphoheptulonate synthase
+
** hydroxymethylglutaryl-coa lyase
 
* ec-number:
 
* ec-number:
** [http://enzyme.expasy.org/EC/2.5.1.54 ec-2.5.1.54]
+
** [http://enzyme.expasy.org/EC/4.1.3.4 ec-4.1.3.4]
 
* direction:
 
* direction:
** reversible
+
** left-to-right
 
== Reaction formula ==
 
== Reaction formula ==
* 1 [[ERYTHROSE-4P]][c] '''+''' 1 [[PHOSPHO-ENOL-PYRUVATE]][c] '''+''' 1 [[WATER]][c] '''<=>''' 1 [[3-DEOXY-D-ARABINO-HEPTULOSONATE-7-P]][c] '''+''' 1 [[Pi]][c]
+
* 1 [[3-HYDROXY-3-METHYL-GLUTARYL-COA]][c] '''=>''' 1 [[3-KETOBUTYRATE]][c] '''+''' 1 [[ACETYL-COA]][c]
 
== Gene(s) associated with this reaction  ==
 
== Gene(s) associated with this reaction  ==
* Gene: [[E_subulatus_16573]]
+
* Gene: [[E_subulatus_22330]]
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[ectocarpus_subulatus]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
*** Source: [[ectocarpus_subulatus]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
Line 16: Line 16:
 
*** Source: [[output_pantograph_a.taliana.aragem]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
*** Source: [[output_pantograph_a.taliana.aragem]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
== Pathway(s)  ==
 
== Pathway(s)  ==
* [[PWY-6164]], 3-dehydroquinate biosynthesis I:
+
* [[LEU-DEG2-PWY]], L-leucine degradation I:
** '''2''' reactions found over '''2''' reactions in the full pathway
+
** '''6''' reactions found over '''6''' reactions in the full pathway
 +
* [[PWY66-367]], ketogenesis:
 +
** '''4''' reactions found over '''5''' reactions in the full pathway
 +
* [[PWY-5074]], mevalonate degradation:
 +
** '''1''' reactions found over '''2''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 +
* category: [[orthology]]; source: [[output_pantograph_a.taliana.aragem]]; tool: [[pantograph]]; comment: n.a
 
* category: [[annotation]]; source: [[ectocarpus_subulatus]]; tool: [[pathwaytools]]; comment: n.a
 
* category: [[annotation]]; source: [[ectocarpus_subulatus]]; tool: [[pathwaytools]]; comment: n.a
* category: [[orthology]]; source: [[output_pantograph_a.taliana.aragem]]; tool: [[pantograph]]; comment: n.a
 
 
== External links  ==
 
== External links  ==
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
+
* METANETX-RXN : MNXR106950
* METANETX-RXN : MNXR97218
 
 
* RHEA:
 
* RHEA:
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=14720 14720]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=24405 24405]
 
* LIGAND-RXN:
 
* LIGAND-RXN:
** [http://www.genome.jp/dbget-bin/www_bget?R01826 R01826]
+
** [http://www.genome.jp/dbget-bin/www_bget?R01360 R01360]
 
* UNIPROT:
 
* UNIPROT:
** [http://www.uniprot.org/uniprot/P0A1B5 P0A1B5]
+
** [http://www.uniprot.org/uniprot/P35914 P35914]
** [http://www.uniprot.org/uniprot/Q9JSQ8 Q9JSQ8]
+
** [http://www.uniprot.org/uniprot/P35915 P35915]
** [http://www.uniprot.org/uniprot/P00887 P00887]
+
** [http://www.uniprot.org/uniprot/Q8L7K2 Q8L7K2]
** [http://www.uniprot.org/uniprot/P0AB91 P0AB91]
+
{{#set: common-name=hydroxymethylglutaryl-coa lyase}}
** [http://www.uniprot.org/uniprot/P00888 P00888]
+
{{#set: ec-number=ec-4.1.3.4}}
** [http://www.uniprot.org/uniprot/Q9PPJ1 Q9PPJ1]
+
{{#set: direction=left-to-right}}
** [http://www.uniprot.org/uniprot/P46245 P46245]
 
** [http://www.uniprot.org/uniprot/P35170 P35170]
 
** [http://www.uniprot.org/uniprot/P44303 P44303]
 
** [http://www.uniprot.org/uniprot/P34725 P34725]
 
** [http://www.uniprot.org/uniprot/P39912 P39912]
 
** [http://www.uniprot.org/uniprot/P14843 P14843]
 
** [http://www.uniprot.org/uniprot/Q02285 Q02285]
 
** [http://www.uniprot.org/uniprot/P32449 P32449]
 
** [http://www.uniprot.org/uniprot/P37215 P37215]
 
** [http://www.uniprot.org/uniprot/P37216 P37216]
 
** [http://www.uniprot.org/uniprot/Q09755 Q09755]
 
** [http://www.uniprot.org/uniprot/Q00218 Q00218]
 
** [http://www.uniprot.org/uniprot/P29976 P29976]
 
** [http://www.uniprot.org/uniprot/Q42921 Q42921]
 
** [http://www.uniprot.org/uniprot/O22407 O22407]
 
** [http://www.uniprot.org/uniprot/O52798 O52798]
 
</div>
 
{{#set: common-name=3-deoxy-7-phosphoheptulonate synthase}}
 
{{#set: ec-number=ec-2.5.1.54}}
 
{{#set: direction=reversible}}
 
 
{{#set: nb gene associated=1}}
 
{{#set: nb gene associated=1}}
{{#set: nb pathway associated=1}}
+
{{#set: nb pathway associated=3}}
 
{{#set: reconstruction category=annotation|orthology}}
 
{{#set: reconstruction category=annotation|orthology}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
{{#set: reconstruction comment=n.a}}
 
{{#set: reconstruction comment=n.a}}
 
{{#set: reconstruction source=output_pantograph_a.taliana.aragem|ectocarpus_subulatus}}
 
{{#set: reconstruction source=output_pantograph_a.taliana.aragem|ectocarpus_subulatus}}

Latest revision as of 19:40, 17 March 2021

Reaction HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN

  • common-name:
    • hydroxymethylglutaryl-coa lyase
  • ec-number:
  • direction:
    • left-to-right

Reaction formula

Gene(s) associated with this reaction

Pathway(s)

  • LEU-DEG2-PWY, L-leucine degradation I:
    • 6 reactions found over 6 reactions in the full pathway
  • PWY66-367, ketogenesis:
    • 4 reactions found over 5 reactions in the full pathway
  • PWY-5074, mevalonate degradation:
    • 1 reactions found over 2 reactions in the full pathway

Reconstruction information

External links