ACETOOHBUTREDUCTOISOM-RXN

Reaction ACETOOHBUTREDUCTOISOM-RXN

• direction:
  • left-to-right
• common-name:
  • ketol-acid reductoisomerase
• ec-number:
  • ec-1.1.1.86

Reaction formula

• 1 2-ACETO-2-HYDROXY-BUTYRATE[c] + 1 NADPH[c] + 1 PROTON[c] => 1 1-KETO-2-METHYLVALERATE[c] + 1 NADP[c]

Gene(s) associated with this reaction

• Gene: RUMFLAFD1_RS0119585
  • Category: annotation
    • Source: genome_a, Tool: pathwaytools, Assignment: automated-name-match, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_faecalibacteriumprausnitziia2-165_heinken2014, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_bifidobacteriumadolescentisl2-32, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_ecoli, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_bthetaiotaomicron_heinken2013, Tool: pantograph, Assignment: n.a, Comment: n.a

Pathway(s)

• ILEUSYN-PWY, L-isoleucine biosynthesis I (from threonine):
  • 7 reactions found over 7 reactions in the full pathway
• PWY-5103, L-isoleucine biosynthesis III:
  • 4 reactions found over 7 reactions in the full pathway

Reconstruction information

• category: annotation; source: genome_a; tool: pathwaytools; comment: n.a
• category: orthology; source: output_pantograph_faecalibacteriumprausnitziia2-165_heinken2014; tool: pantograph; comment: n.a
• category: orthology; source: output_pantograph_ecoli; tool: pantograph; comment: n.a
• category: orthology; source: output_pantograph_bthetaiotaomicron_heinken2013; tool: pantograph; comment: n.a
• category: orthology; source: output_pantograph_bifidobacteriumadolescentisl2-32; tool: pantograph; comment: n.a

External links

• RHEA:
  • 13493
• UNIPROT:
  • P06168
  • P44822
  • O25097
  • Q02138
  • Q57179
  • Q9JTI3
  • Q9PHN5
  • P05793
  • P38674
  • Q59500
  • Q01292
  • Q05758
  • O82043
  • P78827