DIHYDROFOLATEREDUCT-RXN

Reaction DIHYDROFOLATEREDUCT-RXN

• direction:
  • left-to-right
• common-name:
  • dihydrofolate reductase
• ec-number:
  • ec-1.5.1.3

Reaction formula

• 1 DIHYDROFOLATE-GLU-N[c] + 1 NADPH[c] + 1 PROTON[c] => 1 NADP[c] + 1 THF-GLU-N[c]

Gene(s) associated with this reaction

• Gene: SJ02922
  • Category: orthology
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: SJ17385
  • Category: orthology
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: SJ19601
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: ec-number, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: SJ11954
  • Category: orthology
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a

Pathway(s)

• 1CMET2-PWY, folate transformations III (E. coli):
  • 8 reactions found over 9 reactions in the full pathway
• PWY-3841, folate transformations II (plants):
  • 9 reactions found over 11 reactions in the full pathway
• PWY-6614, tetrahydrofolate biosynthesis:
  • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

• category: annotation; source: saccharina_japonica_genome; tool: pathwaytools; comment: n.a
• category: orthology; source: output_pantograph_ectocarpus_siliculosus; tool: pantograph; comment: n.a

External links

• METANETX-RXN : MNXR115841
• RHEA:
  • 15011
• LIGAND-RXN:
  • R00939