Difference between revisions of "2-HYDROXYGLUTARATE-DEHYDROGENASE-RXN"

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(Created page with "Category:reaction == Reaction GLUTAMIN-RXN == * direction: ** left-to-right * common-name: ** glutaminase ** imidazoleglycerol-phosphate synthase ** asparagine synthase (g...")
(Created page with "Category:reaction == Reaction 2-HYDROXYGLUTARATE-DEHYDROGENASE-RXN == * direction: ** reversible * common-name: ** 2-hydroxyglutarate dehydrogenase * ec-number: ** [http:/...")
 
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[[Category:reaction]]
 
[[Category:reaction]]
== Reaction GLUTAMIN-RXN ==
+
== Reaction 2-HYDROXYGLUTARATE-DEHYDROGENASE-RXN ==
 
* direction:
 
* direction:
** left-to-right
+
** reversible
 
* common-name:
 
* common-name:
** glutaminase
+
** 2-hydroxyglutarate dehydrogenase
** imidazoleglycerol-phosphate synthase
 
** asparagine synthase (glutamine-hydrolyzing)
 
 
* ec-number:
 
* ec-number:
** [http://enzyme.expasy.org/EC/3.5.1.38 ec-3.5.1.38]
+
** [http://enzyme.expasy.org/EC/1.1.99.2 ec-1.1.99.2]
** [http://enzyme.expasy.org/EC/3.5.1.2 ec-3.5.1.2]
 
 
== Reaction formula ==
 
== Reaction formula ==
* 1 [[GLN]][c] '''+''' 1 [[WATER]][c] '''=>''' 1 [[AMMONIUM]][c] '''+''' 1 [[GLT]][c]
+
* 1 [[Acceptor]][c] '''+''' 1 [[CPD-381]][c] '''<=>''' 1 [[2-KETOGLUTARATE]][c] '''+''' 1 [[Donor-H2]][c]
 
== Gene(s) associated with this reaction  ==
 
== Gene(s) associated with this reaction  ==
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
+
* Gene: [[SJ22039]]
* Gene: [[SJ13639]]
 
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
** Category: [[orthology]]
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
* Gene: [[SJ04922]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
** Category: [[orthology]]
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
* Gene: [[SJ13463]]
 
** Category: [[orthology]]
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
* Gene: [[SJ17851]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
** Category: [[orthology]]
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
* Gene: [[SJ22095]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
** Category: [[orthology]]
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
* Gene: [[SJ13939]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
* Gene: [[SJ15949]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
* Gene: [[SJ22386]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
** Category: [[orthology]]
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
* Gene: [[SJ12953]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
* Gene: [[SJ20190]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
* Gene: [[SJ19186]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
* Gene: [[SJ19163]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
* Gene: [[SJ09511]]
 
** Category: [[orthology]]
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
* Gene: [[SJ20196]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
* Gene: [[SJ08788]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
* Gene: [[SJ07094]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
* Gene: [[SJ10812]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
** Category: [[orthology]]
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
* Gene: [[SJ10813]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
* Gene: [[SJ04921]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
* Gene: [[SJ10267]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
** Category: [[orthology]]
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
* Gene: [[SJ13618]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
* Gene: [[SJ07729]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
** Category: [[orthology]]
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
* Gene: [[SJ12700]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
</div>
 
 
== Pathway(s)  ==
 
== Pathway(s)  ==
* [[CITRULBIO-PWY]], L-citrulline biosynthesis:
 
** '''7''' reactions found over '''8''' reactions in the full pathway
 
* [[GLUTAMINDEG-PWY]], L-glutamine degradation I:
 
** '''1''' reactions found over '''1''' reactions in the full pathway
 
 
== Reconstruction information  ==
 
== Reconstruction information  ==
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
 
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 
== External links  ==
 
== External links  ==
* METANETX-RXN : MNXR100030
+
* METANETX-RXN : MNXR115023
 +
* RHEA:
 +
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=21252 21252]
 
* LIGAND-RXN:
 
* LIGAND-RXN:
** [http://www.genome.jp/dbget-bin/www_bget?R00256 R00256]
+
** [http://www.genome.jp/dbget-bin/www_bget?R00298 R00298]
* RHEA:
+
{{#set: direction=reversible}}
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=15890 15890]
+
{{#set: common-name=2-hydroxyglutarate dehydrogenase}}
* UNIPROT:
+
{{#set: ec-number=ec-1.1.99.2}}
** [http://www.uniprot.org/uniprot/P10172 P10172]
+
{{#set: nb gene associated=1}}
** [http://www.uniprot.org/uniprot/P28492 P28492]
+
{{#set: nb pathway associated=0}}
{{#set: direction=left-to-right}}
+
{{#set: reconstruction category=annotation}}
{{#set: common-name=asparagine synthase (glutamine-hydrolyzing)|glutaminase|imidazoleglycerol-phosphate synthase}}
+
{{#set: reconstruction tool=pathwaytools}}
{{#set: ec-number=ec-3.5.1.38|ec-3.5.1.2}}
 
{{#set: nb gene associated=23}}
 
{{#set: nb pathway associated=2}}
 
{{#set: reconstruction category=orthology|annotation}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
 
{{#set: reconstruction comment=n.a}}
 
{{#set: reconstruction comment=n.a}}
{{#set: reconstruction source=output_pantograph_ectocarpus_siliculosus|saccharina_japonica_genome}}
+
{{#set: reconstruction source=saccharina_japonica_genome}}

Latest revision as of 11:18, 18 March 2021

Reaction 2-HYDROXYGLUTARATE-DEHYDROGENASE-RXN

  • direction:
    • reversible
  • common-name:
    • 2-hydroxyglutarate dehydrogenase
  • ec-number:

Reaction formula

Gene(s) associated with this reaction

Pathway(s)

Reconstruction information

External links

  • METANETX-RXN : MNXR115023
  • RHEA:
  • LIGAND-RXN: