Difference between revisions of "DIHYDROFOLATEREDUCT-RXN"

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(Created page with "Category:reaction == Reaction UROGENIIISYN-RXN == * direction: ** left-to-right * common-name: ** uroporphyrinogen iii synthase * ec-number: ** [http://enzyme.expasy.org/E...")
(Created page with "Category:reaction == Reaction DIHYDROFOLATEREDUCT-RXN == * direction: ** left-to-right * common-name: ** dihydrofolate reductase * ec-number: ** [http://enzyme.expasy.org/...")
 
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[[Category:reaction]]
 
[[Category:reaction]]
== Reaction UROGENIIISYN-RXN ==
+
== Reaction DIHYDROFOLATEREDUCT-RXN ==
 
* direction:
 
* direction:
 
** left-to-right
 
** left-to-right
 
* common-name:
 
* common-name:
** uroporphyrinogen iii synthase
+
** dihydrofolate reductase
 
* ec-number:
 
* ec-number:
** [http://enzyme.expasy.org/EC/4.2.1.75 ec-4.2.1.75]
+
** [http://enzyme.expasy.org/EC/1.5.1.3 ec-1.5.1.3]
 
== Reaction formula ==
 
== Reaction formula ==
* 1 [[HYDROXYMETHYLBILANE]][c] '''=>''' 1 [[UROPORPHYRINOGEN-III]][c] '''+''' 1 [[WATER]][c]
+
* 1 [[DIHYDROFOLATE-GLU-N]][c] '''+''' 1 [[NADPH]][c] '''+''' 1 [[PROTON]][c] '''=>''' 1 [[NADP]][c] '''+''' 1 [[THF-GLU-N]][c]
 
== Gene(s) associated with this reaction  ==
 
== Gene(s) associated with this reaction  ==
* Gene: [[SJ19532]]
+
* Gene: [[SJ02922]]
 +
** Category: [[orthology]]
 +
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 +
* Gene: [[SJ17385]]
 +
** Category: [[orthology]]
 +
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 +
* Gene: [[SJ19601]]
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
** Category: [[orthology]]
 
** Category: [[orthology]]
*** Source: [[output_pantograph_nannochloropsis_salina]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
+
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 +
* Gene: [[SJ11954]]
 +
** Category: [[orthology]]
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
== Pathway(s)  ==
 
== Pathway(s)  ==
* [[PWY-5189]], tetrapyrrole biosynthesis II (from glycine):
+
* [[1CMET2-PWY]], folate transformations III (E. coli):
** '''3''' reactions found over '''4''' reactions in the full pathway
+
** '''8''' reactions found over '''9''' reactions in the full pathway
* [[PWY-5188]], tetrapyrrole biosynthesis I (from glutamate):
+
* [[PWY-3841]], folate transformations II (plants):
** '''6''' reactions found over '''6''' reactions in the full pathway
+
** '''9''' reactions found over '''11''' reactions in the full pathway
 +
* [[PWY-6614]], tetrahydrofolate biosynthesis:
 +
** '''3''' reactions found over '''3''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 +
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
 
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
* category: [[orthology]]; source: [[output_pantograph_nannochloropsis_salina]]; tool: [[pantograph]]; comment: n.a
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 
 
== External links  ==
 
== External links  ==
 +
* METANETX-RXN : MNXR115841
 
* RHEA:
 
* RHEA:
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=18965 18965]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=15011 15011]
 
* LIGAND-RXN:
 
* LIGAND-RXN:
** [http://www.genome.jp/dbget-bin/www_bget?R03165 R03165]
+
** [http://www.genome.jp/dbget-bin/www_bget?R00939 R00939]
* UNIPROT:
 
** [http://www.uniprot.org/uniprot/P10746 P10746]
 
** [http://www.uniprot.org/uniprot/P51163 P51163]
 
** [http://www.uniprot.org/uniprot/P21248 P21248]
 
** [http://www.uniprot.org/uniprot/Q58401 Q58401]
 
** [http://www.uniprot.org/uniprot/P09126 P09126]
 
** [http://www.uniprot.org/uniprot/Q59294 Q59294]
 
 
{{#set: direction=left-to-right}}
 
{{#set: direction=left-to-right}}
{{#set: common-name=uroporphyrinogen iii synthase}}
+
{{#set: common-name=dihydrofolate reductase}}
{{#set: ec-number=ec-4.2.1.75}}
+
{{#set: ec-number=ec-1.5.1.3}}
{{#set: nb gene associated=1}}
+
{{#set: nb gene associated=4}}
{{#set: nb pathway associated=2}}
+
{{#set: nb pathway associated=3}}
{{#set: reconstruction category=annotation|orthology}}
+
{{#set: reconstruction category=orthology|annotation}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
{{#set: reconstruction comment=n.a}}
 
{{#set: reconstruction comment=n.a}}
{{#set: reconstruction source=saccharina_japonica_genome|output_pantograph_ectocarpus_siliculosus|output_pantograph_nannochloropsis_salina}}
+
{{#set: reconstruction source=output_pantograph_ectocarpus_siliculosus|saccharina_japonica_genome}}

Latest revision as of 11:22, 18 March 2021

Reaction DIHYDROFOLATEREDUCT-RXN

  • direction:
    • left-to-right
  • common-name:
    • dihydrofolate reductase
  • ec-number:

Reaction formula

Gene(s) associated with this reaction

Pathway(s)

  • 1CMET2-PWY, folate transformations III (E. coli):
    • 8 reactions found over 9 reactions in the full pathway
  • PWY-3841, folate transformations II (plants):
    • 9 reactions found over 11 reactions in the full pathway
  • PWY-6614, tetrahydrofolate biosynthesis:
    • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

External links

  • METANETX-RXN : MNXR115841
  • RHEA:
  • LIGAND-RXN: