Difference between revisions of "RXN-8642"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=3-ISOPROPYLMALDEHYDROG-RXN 3-ISOPROPYLMALDEHYDROG-RXN] == * common name: ** 3-isopropylmalate dehyd...")
 
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-8642 RXN-8642] == * common name: ** NADP-dependent isocitrate dehydrogenase * direction: ** REV...")
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
−
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=3-ISOPROPYLMALDEHYDROG-RXN 3-ISOPROPYLMALDEHYDROG-RXN] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-8642 RXN-8642] ==
 
* common name:
 
* common name:
−
** 3-isopropylmalate dehydrogenase
+
** NADP-dependent isocitrate dehydrogenase
 
* direction:
 
* direction:
 
** REVERSIBLE
 
** REVERSIBLE
 
* Synonym(s):
 
* Synonym(s):
−
** β-isopropylmalic enzyme
+
** oxalsuccinic decarboxylase
−
** threo-Ds-3-isopropylmalate dehydrogenase
+
** isocitrate (NADP) dehydrogenase
 +
** isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase
 +
** NADP-specific isocitrate dehydrogenase
 +
** NADP-linked isocitrate dehydrogenase
 +
** NADP isocitric dehydrogenase
 +
** isocitrate dehydrogenase (NADP-dependent)
 +
** NADP-dependent isocitric dehydrogenase
 +
** triphosphopyridine nucleotide-linked isocitrate dehydrogenase-oxalosuccinate carboxylase
 +
** NADP+-linked isocitrate dehydrogenase
 +
** IDH (ambiguous)
 +
** dual-cofactor-specific isocitrate dehydrogenase
 +
** NADP+-ICDH
 +
** NADP+-IDH
 +
** IDP
 +
** IDP1
 +
** IDP2
 +
** IDP3
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1 [[2-D-THREO-HYDROXY-3-CARBOXY-ISOCAPROATE]][c] '''+''' 1 [[NAD]][c] '''<=>''' 1 [[CPD-7100]][c] '''+''' 1 [[NADH]][c] '''+''' 1 [[PROTON]][c]
+
** 1 [[OXALO-SUCCINATE]][c] '''+''' 1 [[PROTON]][c] '''<=>''' 1 [[2-KETOGLUTARATE]][c] '''+''' 1 [[CARBON-DIOXIDE]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1 (2R,3S)-3-isopropylmalate[c] '''+''' 1 NAD+[c] '''<=>''' 1 (2S)-2-isopropyl-3-oxosuccinate[c] '''+''' 1 NADH[c] '''+''' 1 H+[c]
+
** 1 oxalosuccinate[c] '''+''' 1 H+[c] '''<=>''' 1 2-oxoglutarate[c] '''+''' 1 CO2[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
−
* Gene: [[DN21092_c0_g1_i1]]
+
* Gene: [[DN18221_c0_g1_i2]]
 +
** Source: [[annotation-transcriptome]]
 +
*** Assignment: EC-NUMBER
 +
* Gene: [[DN21544_c0_g1_i1]]
 
** Source: [[annotation-transcriptome]]
 
** Source: [[annotation-transcriptome]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
 
== Pathways  ==
 
== Pathways  ==
−
* [[PWY-6871]], 3-methylbutanol biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6871 PWY-6871]
 
−
** '''4''' reactions found over '''NA''' reactions in the full pathway
 
−
* [[LEUSYN-PWY]], L-leucine biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=LEUSYN-PWY LEUSYN-PWY]
 
−
** '''5''' reactions found over '''NA''' reactions in the full pathway
 
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 
* Category: [[annotation]]
 
* Category: [[annotation]]
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== External links  ==
 
== External links  ==
 
* RHEA:
 
* RHEA:
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=10895 10895]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=19384 19384]
 
* LIGAND-RXN:
 
* LIGAND-RXN:
−
** [http://www.genome.jp/dbget-bin/www_bget?R04426 R04426]
+
** [http://www.genome.jp/dbget-bin/www_bget?R00268 R00268]
−
* UNIPROT:
+
{{#set: common name=NADP-dependent isocitrate dehydrogenase}}
−
** [http://www.uniprot.org/uniprot/P05644 P05644]
 
−
** [http://www.uniprot.org/uniprot/P05645 P05645]
 
−
** [http://www.uniprot.org/uniprot/Q01987 Q01987]
 
−
** [http://www.uniprot.org/uniprot/Q00412 Q00412]
 
−
** [http://www.uniprot.org/uniprot/P08791 P08791]
 
−
** [http://www.uniprot.org/uniprot/P30125 P30125]
 
−
** [http://www.uniprot.org/uniprot/Q9PLW0 Q9PLW0]
 
−
** [http://www.uniprot.org/uniprot/O66607 O66607]
 
−
** [http://www.uniprot.org/uniprot/P12010 P12010]
 
−
** [http://www.uniprot.org/uniprot/P04173 P04173]
 
−
** [http://www.uniprot.org/uniprot/Q5SIY4 Q5SIY4]
 
−
** [http://www.uniprot.org/uniprot/P24098 P24098]
 
−
** [http://www.uniprot.org/uniprot/Q9JU79 Q9JU79]
 
−
** [http://www.uniprot.org/uniprot/P43860 P43860]
 
−
** [http://www.uniprot.org/uniprot/P41019 P41019]
 
−
** [http://www.uniprot.org/uniprot/P54354 P54354]
 
−
** [http://www.uniprot.org/uniprot/Q56268 Q56268]
 
−
** [http://www.uniprot.org/uniprot/P29102 P29102]
 
−
** [http://www.uniprot.org/uniprot/P37412 P37412]
 
−
** [http://www.uniprot.org/uniprot/P23390 P23390]
 
−
** [http://www.uniprot.org/uniprot/P29696 P29696]
 
−
** [http://www.uniprot.org/uniprot/P41766 P41766]
 
−
** [http://www.uniprot.org/uniprot/Q02143 Q02143]
 
−
** [http://www.uniprot.org/uniprot/P34733 P34733]
 
−
** [http://www.uniprot.org/uniprot/P50180 P50180]
 
−
** [http://www.uniprot.org/uniprot/Q12591 Q12591]
 
−
** [http://www.uniprot.org/uniprot/Q12590 Q12590]
 
−
** [http://www.uniprot.org/uniprot/Q12592 Q12592]
 
−
** [http://www.uniprot.org/uniprot/P07139 P07139]
 
−
** [http://www.uniprot.org/uniprot/P41926 P41926]
 
−
** [http://www.uniprot.org/uniprot/P48012 P48012]
 
−
** [http://www.uniprot.org/uniprot/P87256 P87256]
 
−
** [http://www.uniprot.org/uniprot/P87257 P87257]
 
−
** [http://www.uniprot.org/uniprot/P73960 P73960]
 
−
** [http://www.uniprot.org/uniprot/O86504 O86504]
 
−
** [http://www.uniprot.org/uniprot/O85837 O85837]
 
−
** [http://www.uniprot.org/uniprot/P18869 P18869]
 
−
** [http://www.uniprot.org/uniprot/P34738 P34738]
 
−
{{#set: common name=3-isopropylmalate dehydrogenase}}
 
 
{{#set: direction=REVERSIBLE}}
 
{{#set: direction=REVERSIBLE}}
−
{{#set: common name=&beta;-isopropylmalic enzyme|threo-Ds-3-isopropylmalate dehydrogenase}}
+
{{#set: common name=oxalsuccinic decarboxylase|isocitrate (NADP) dehydrogenase|isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase|NADP-specific isocitrate dehydrogenase|NADP-linked isocitrate dehydrogenase|NADP isocitric dehydrogenase|isocitrate dehydrogenase (NADP-dependent)|NADP-dependent isocitric dehydrogenase|triphosphopyridine nucleotide-linked isocitrate dehydrogenase-oxalosuccinate carboxylase|NADP+-linked isocitrate dehydrogenase|IDH (ambiguous)|dual-cofactor-specific isocitrate dehydrogenase|NADP+-ICDH|NADP+-IDH|IDP|IDP1|IDP2|IDP3}}
−
{{#set: gene associated=DN21092_c0_g1_i1}}
+
{{#set: gene associated=DN18221_c0_g1_i2|DN21544_c0_g1_i1}}
−
{{#set: in pathway=PWY-6871|LEUSYN-PWY}}
+
{{#set: in pathway=}}
 
{{#set: reconstruction category=annotation}}
 
{{#set: reconstruction category=annotation}}
 
{{#set: reconstruction source=annotation-transcriptome}}
 
{{#set: reconstruction source=annotation-transcriptome}}
 
{{#set: reconstruction tool=pathwaytools}}
 
{{#set: reconstruction tool=pathwaytools}}

Latest revision as of 14:21, 15 January 2021

Reaction RXN-8642

  • common name:
    • NADP-dependent isocitrate dehydrogenase
  • direction:
    • REVERSIBLE
  • Synonym(s):
    • oxalsuccinic decarboxylase
    • isocitrate (NADP) dehydrogenase
    • isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase
    • NADP-specific isocitrate dehydrogenase
    • NADP-linked isocitrate dehydrogenase
    • NADP isocitric dehydrogenase
    • isocitrate dehydrogenase (NADP-dependent)
    • NADP-dependent isocitric dehydrogenase
    • triphosphopyridine nucleotide-linked isocitrate dehydrogenase-oxalosuccinate carboxylase
    • NADP+-linked isocitrate dehydrogenase
    • IDH (ambiguous)
    • dual-cofactor-specific isocitrate dehydrogenase
    • NADP+-ICDH
    • NADP+-IDH
    • IDP
    • IDP1
    • IDP2
    • IDP3

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

Reconstruction information

External links





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