Difference between revisions of "GLUTCYSLIG-RXN"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN0-2381 RXN0-2381] == * common name: ** indoleglycerol phosphate aldolase * ec number: ** [http:/...")
 
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=GLUTCYSLIG-RXN GLUTCYSLIG-RXN] == * common name: ** glutamate—cysteine ligase * ec number: **...")
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
−
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN0-2381 RXN0-2381] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=GLUTCYSLIG-RXN GLUTCYSLIG-RXN] ==
 
* common name:
 
* common name:
−
** indoleglycerol phosphate aldolase
+
** glutamate—cysteine ligase
 
* ec number:
 
* ec number:
−
** [http://enzyme.expasy.org/EC/4.1.2.8 EC-4.1.2.8]
+
** [http://enzyme.expasy.org/EC/6.3.2.2 EC-6.3.2.2]
 
* direction:
 
* direction:
−
** REVERSIBLE
+
** LEFT-TO-RIGHT
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1 [[INDOLE-3-GLYCEROL-P]][c] '''<=>''' 1 [[INDOLE]][c] '''+''' 1 [[GAP]][c]
+
** 1 [[GLT]][c] '''+''' 1 [[CYS]][c] '''+''' 1 [[ATP]][c] '''=>''' 1 [[PROTON]][c] '''+''' 1 [[L-GAMMA-GLUTAMYLCYSTEINE]][c] '''+''' 1 [[Pi]][c] '''+''' 1 [[ADP]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1 (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate[c] '''<=>''' 1 indole[c] '''+''' 1 D-glyceraldehyde 3-phosphate[c]
+
** 1 L-glutamate[c] '''+''' 1 L-cysteine[c] '''+''' 1 ATP[c] '''=>''' 1 H+[c] '''+''' 1 &gamma;-L-glutamyl-L-cysteine[c] '''+''' 1 phosphate[c] '''+''' 1 ADP[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
−
* Gene: [[DN19913_c0_g1_i1]]
+
* Gene: [[DN22751_c0_g1_i1]]
 
** Source: [[annotation-transcriptome]]
 
** Source: [[annotation-transcriptome]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
−
* Gene: [[DN15376_c0_g1_i1]]
+
* Gene: [[DN21286_c0_g2_i1]]
 
** Source: [[annotation-transcriptome]]
 
** Source: [[annotation-transcriptome]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
−
* Gene: [[DN15376_c0_g1_i2]]
+
* Gene: [[DN22751_c0_g4_i1]]
−
** Source: [[annotation-transcriptome]]
 
−
*** Assignment: EC-NUMBER
 
−
* Gene: [[DN17689_c0_g1_i1]]
 
 
** Source: [[annotation-transcriptome]]
 
** Source: [[annotation-transcriptome]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
 
== Pathways  ==
 
== Pathways  ==
−
* [[PWY-6949]], DIBOA-glucoside biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6949 PWY-6949]
+
* [[GLUTATHIONESYN-PWY]], glutathione biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=GLUTATHIONESYN-PWY GLUTATHIONESYN-PWY]
 +
** '''2''' reactions found over '''NA''' reactions in the full pathway
 +
* [[PWY-7255]], ergothioneine biosynthesis I (bacteria): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7255 PWY-7255]
 +
** '''1''' reactions found over '''NA''' reactions in the full pathway
 +
* [[PWY-6840]], homoglutathione biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6840 PWY-6840]
 
** '''1''' reactions found over '''NA''' reactions in the full pathway
 
** '''1''' reactions found over '''NA''' reactions in the full pathway
−
* [[TRPSYN-PWY]], L-tryptophan biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=TRPSYN-PWY TRPSYN-PWY]
 
−
** '''5''' reactions found over '''NA''' reactions in the full pathway
 
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 
* Category: [[annotation]]
 
* Category: [[annotation]]
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== External links  ==
 
== External links  ==
 
* RHEA:
 
* RHEA:
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=14084 14084]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=13286 13286]
 
* LIGAND-RXN:
 
* LIGAND-RXN:
−
** [http://www.genome.jp/dbget-bin/www_bget?R02340 R02340]
+
** [http://www.genome.jp/dbget-bin/www_bget?R00894 R00894]
−
{{#set: common name=indoleglycerol phosphate aldolase}}
+
* UNIPROT:
−
{{#set: ec number=EC-4.1.2.8}}
+
** [http://www.uniprot.org/uniprot/P19468 P19468]
−
{{#set: direction=REVERSIBLE}}
+
** [http://www.uniprot.org/uniprot/Q56277 Q56277]
−
{{#set: gene associated=DN19913_c0_g1_i1|DN15376_c0_g1_i1|DN15376_c0_g1_i2|DN17689_c0_g1_i1}}
+
** [http://www.uniprot.org/uniprot/Q9JZI4 Q9JZI4]
−
{{#set: in pathway=PWY-6949|TRPSYN-PWY}}
+
** [http://www.uniprot.org/uniprot/Q9JU83 Q9JU83]
 +
** [http://www.uniprot.org/uniprot/P48507 P48507]
 +
** [http://www.uniprot.org/uniprot/P48506 P48506]
 +
** [http://www.uniprot.org/uniprot/P32477 P32477]
 +
** [http://www.uniprot.org/uniprot/P0A6W9 P0A6W9]
 +
** [http://www.uniprot.org/uniprot/O22493 O22493]
 +
** [http://www.uniprot.org/uniprot/P46309 P46309]
 +
** [http://www.uniprot.org/uniprot/Q9TY17 Q9TY17]
 +
** [http://www.uniprot.org/uniprot/Q09768 Q09768]
 +
{{#set: common name=glutamate&mdash;cysteine ligase}}
 +
{{#set: ec number=EC-6.3.2.2}}
 +
{{#set: direction=LEFT-TO-RIGHT}}
 +
{{#set: gene associated=DN22751_c0_g1_i1|DN21286_c0_g2_i1|DN22751_c0_g4_i1}}
 +
{{#set: in pathway=GLUTATHIONESYN-PWY|PWY-7255|PWY-6840}}
 
{{#set: reconstruction category=annotation}}
 
{{#set: reconstruction category=annotation}}
 
{{#set: reconstruction source=annotation-transcriptome}}
 
{{#set: reconstruction source=annotation-transcriptome}}
 
{{#set: reconstruction tool=pathwaytools}}
 
{{#set: reconstruction tool=pathwaytools}}

Latest revision as of 14:22, 15 January 2021

Reaction GLUTCYSLIG-RXN

  • common name:
    • glutamate—cysteine ligase
  • ec number:
  • direction:
    • LEFT-TO-RIGHT
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 L-glutamate[c] + 1 L-cysteine[c] + 1 ATP[c] => 1 H+[c] + 1 γ-L-glutamyl-L-cysteine[c] + 1 phosphate[c] + 1 ADP[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • GLUTATHIONESYN-PWY, glutathione biosynthesis: GLUTATHIONESYN-PWY
    • 2 reactions found over NA reactions in the full pathway
  • PWY-7255, ergothioneine biosynthesis I (bacteria): PWY-7255
    • 1 reactions found over NA reactions in the full pathway
  • PWY-6840, homoglutathione biosynthesis: PWY-6840
    • 1 reactions found over NA reactions in the full pathway

Reconstruction information

External links





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