Difference between revisions of "THYMIDYLATESYN-RXN"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=GLYRIBONUCSYN-RXN GLYRIBONUCSYN-RXN] == * common name: ** phosphoribosylamine—glycine ligase...")
 
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=THYMIDYLATESYN-RXN THYMIDYLATESYN-RXN] == * common name: ** thymidylate synthase * ec number: ** [h...")
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
−
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=GLYRIBONUCSYN-RXN GLYRIBONUCSYN-RXN] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=THYMIDYLATESYN-RXN THYMIDYLATESYN-RXN] ==
 
* common name:
 
* common name:
−
** phosphoribosylamine—glycine ligase
+
** thymidylate synthase
 
* ec number:
 
* ec number:
−
** [http://enzyme.expasy.org/EC/6.3.4.13 EC-6.3.4.13]
+
** [http://enzyme.expasy.org/EC/2.1.1.45 EC-2.1.1.45]
 
* direction:
 
* direction:
 
** LEFT-TO-RIGHT
 
** LEFT-TO-RIGHT
Line 11: Line 11:
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1 [[5-P-BETA-D-RIBOSYL-AMINE]][c] '''+''' 1 [[ATP]][c] '''+''' 1 [[GLY]][c] '''=>''' 1 [[Pi]][c] '''+''' 1 [[5-PHOSPHO-RIBOSYL-GLYCINEAMIDE]][c] '''+''' 1 [[PROTON]][c] '''+''' 1 [[ADP]][c]
+
** 1 [[METHYLENE-THF-GLU-N]][c] '''+''' 1 [[DUMP]][c] '''=>''' 1 [[TMP]][c] '''+''' 1 [[DIHYDROFOLATE-GLU-N]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1 5-phospho-β-D-ribosylamine[c] '''+''' 1 ATP[c] '''+''' 1 glycine[c] '''=>''' 1 phosphate[c] '''+''' 1 N1-(5-phospho-β-D-ribosyl)glycinamide[c] '''+''' 1 H+[c] '''+''' 1 ADP[c]
+
** 1 a 5,10-methylene-tetrahydrofolate[c] '''+''' 1 dUMP[c] '''=>''' 1 dTMP[c] '''+''' 1 a 7,8-dihydrofolate[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
−
* Gene: [[DN31758_c0_g1_i1]]
+
* Gene: [[DN21081_c0_g1_i2]]
 
** Source: [[annotation-transcriptome]]
 
** Source: [[annotation-transcriptome]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
 
== Pathways  ==
 
== Pathways  ==
−
* [[PWY-6121]], 5-aminoimidazole ribonucleotide biosynthesis I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6121 PWY-6121]
+
* [[PWY-3841]], folate transformations II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-3841 PWY-3841]
−
** '''5''' reactions found over '''NA''' reactions in the full pathway
+
** '''7''' reactions found over '''NA''' reactions in the full pathway
−
* [[PWY-6122]], 5-aminoimidazole ribonucleotide biosynthesis II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6122 PWY-6122]
+
* [[PWY0-166]], superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli): [http://metacyc.org/META/NEW-IMAGE?object=PWY0-166 PWY0-166]
 +
** '''12''' reactions found over '''NA''' reactions in the full pathway
 +
* [[PWY-7187]], pyrimidine deoxyribonucleotides de novo biosynthesis II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7187 PWY-7187]
 
** '''4''' reactions found over '''NA''' reactions in the full pathway
 
** '''4''' reactions found over '''NA''' reactions in the full pathway
−
* [[PWY-6277]], superpathway of 5-aminoimidazole ribonucleotide biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6277 PWY-6277]
+
* [[1CMET2-PWY]], N10-formyl-tetrahydrofolate biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=1CMET2-PWY 1CMET2-PWY]
 +
** '''6''' reactions found over '''NA''' reactions in the full pathway
 +
* [[PWY-7184]], pyrimidine deoxyribonucleotides de novo biosynthesis I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7184 PWY-7184]
 +
** '''9''' reactions found over '''NA''' reactions in the full pathway
 +
* [[PWY-7199]], pyrimidine deoxyribonucleosides salvage: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7199 PWY-7199]
 +
** '''2''' reactions found over '''NA''' reactions in the full pathway
 +
* [[PWY-7198]], pyrimidine deoxyribonucleotides de novo biosynthesis IV: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7198 PWY-7198]
 +
** '''6''' reactions found over '''NA''' reactions in the full pathway
 +
* [[PWY-7210]], pyrimidine deoxyribonucleotides biosynthesis from CTP: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7210 PWY-7210]
 
** '''6''' reactions found over '''NA''' reactions in the full pathway
 
** '''6''' reactions found over '''NA''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
Line 33: Line 43:
 
== External links  ==
 
== External links  ==
 
* RHEA:
 
* RHEA:
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=17453 17453]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=12105 12105]
 
* LIGAND-RXN:
 
* LIGAND-RXN:
−
** [http://www.genome.jp/dbget-bin/www_bget?R04144 R04144]
+
** [http://www.genome.jp/dbget-bin/www_bget?R02101 R02101]
 
* UNIPROT:
 
* UNIPROT:
−
** [http://www.uniprot.org/uniprot/P07244 P07244]
+
** [http://www.uniprot.org/uniprot/P19368 P19368]
−
** [http://www.uniprot.org/uniprot/Q58347 Q58347]
+
** [http://www.uniprot.org/uniprot/Q07422 Q07422]
−
** [http://www.uniprot.org/uniprot/P12039 P12039]
+
** [http://www.uniprot.org/uniprot/P47469 P47469]
−
** [http://www.uniprot.org/uniprot/P21872 P21872]
+
** [http://www.uniprot.org/uniprot/Q9JT57 Q9JT57]
−
** [http://www.uniprot.org/uniprot/P15640 P15640]
+
** [http://www.uniprot.org/uniprot/P42326 P42326]
−
** [http://www.uniprot.org/uniprot/P00967 P00967]
+
** [http://www.uniprot.org/uniprot/O02604 O02604]
−
** [http://www.uniprot.org/uniprot/P16340 P16340]
+
** [http://www.uniprot.org/uniprot/P07382 P07382]
−
** [http://www.uniprot.org/uniprot/P22102 P22102]
+
** [http://www.uniprot.org/uniprot/P16126 P16126]
−
** [http://www.uniprot.org/uniprot/Q9JWU6 Q9JWU6]
+
** [http://www.uniprot.org/uniprot/P13922 P13922]
−
** [http://www.uniprot.org/uniprot/P43845 P43845]
+
** [http://www.uniprot.org/uniprot/P20712 P20712]
−
** [http://www.uniprot.org/uniprot/Q9PN47 Q9PN47]
+
** [http://www.uniprot.org/uniprot/P11044 P11044]
−
** [http://www.uniprot.org/uniprot/Q64737 Q64737]
+
** [http://www.uniprot.org/uniprot/P45350 P45350]
−
** [http://www.uniprot.org/uniprot/P20772 P20772]
+
** [http://www.uniprot.org/uniprot/P45352 P45352]
−
** [http://www.uniprot.org/uniprot/P26977 P26977]
+
** [http://www.uniprot.org/uniprot/P51820 P51820]
−
** [http://www.uniprot.org/uniprot/Q59492 Q59492]
+
** [http://www.uniprot.org/uniprot/P0C0M4 P0C0M4]
−
** [http://www.uniprot.org/uniprot/P74232 P74232]
+
** [http://www.uniprot.org/uniprot/Q27828 Q27828]
−
** [http://www.uniprot.org/uniprot/Q42804 Q42804]
+
** [http://www.uniprot.org/uniprot/P09249 P09249]
−
** [http://www.uniprot.org/uniprot/P52421 P52421]
+
** [http://www.uniprot.org/uniprot/P12462 P12462]
−
{{#set: common name=phosphoribosylamine—glycine ligase}}
+
** [http://www.uniprot.org/uniprot/P07606 P07606]
−
{{#set: ec number=EC-6.3.4.13}}
+
** [http://www.uniprot.org/uniprot/P00471 P00471]
 +
** [http://www.uniprot.org/uniprot/P0A884 P0A884]
 +
** [http://www.uniprot.org/uniprot/P00469 P00469]
 +
** [http://www.uniprot.org/uniprot/O81395 O81395]
 +
** [http://www.uniprot.org/uniprot/Q05763 Q05763]
 +
** [http://www.uniprot.org/uniprot/Q39687 Q39687]
 +
** [http://www.uniprot.org/uniprot/Q9YTJ6 Q9YTJ6]
 +
** [http://www.uniprot.org/uniprot/P06785 P06785]
 +
** [http://www.uniprot.org/uniprot/P04818 P04818]
 +
** [http://www.uniprot.org/uniprot/P07607 P07607]
 +
** [http://www.uniprot.org/uniprot/P13100 P13100]
 +
{{#set: common name=thymidylate synthase}}
 +
{{#set: ec number=EC-2.1.1.45}}
 
{{#set: direction=LEFT-TO-RIGHT}}
 
{{#set: direction=LEFT-TO-RIGHT}}
−
{{#set: gene associated=DN31758_c0_g1_i1}}
+
{{#set: gene associated=DN21081_c0_g1_i2}}
−
{{#set: in pathway=PWY-6121|PWY-6122|PWY-6277}}
+
{{#set: in pathway=PWY-3841|PWY0-166|PWY-7187|1CMET2-PWY|PWY-7184|PWY-7199|PWY-7198|PWY-7210}}
 
{{#set: reconstruction category=annotation}}
 
{{#set: reconstruction category=annotation}}
 
{{#set: reconstruction source=annotation-transcriptome}}
 
{{#set: reconstruction source=annotation-transcriptome}}
 
{{#set: reconstruction tool=pathwaytools}}
 
{{#set: reconstruction tool=pathwaytools}}

Latest revision as of 14:22, 15 January 2021

Reaction THYMIDYLATESYN-RXN

  • common name:
    • thymidylate synthase
  • ec number:
  • direction:
    • LEFT-TO-RIGHT
  • Synonym(s):

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-3841, folate transformations II: PWY-3841
    • 7 reactions found over NA reactions in the full pathway
  • PWY0-166, superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli): PWY0-166
    • 12 reactions found over NA reactions in the full pathway
  • PWY-7187, pyrimidine deoxyribonucleotides de novo biosynthesis II: PWY-7187
    • 4 reactions found over NA reactions in the full pathway
  • 1CMET2-PWY, N10-formyl-tetrahydrofolate biosynthesis: 1CMET2-PWY
    • 6 reactions found over NA reactions in the full pathway
  • PWY-7184, pyrimidine deoxyribonucleotides de novo biosynthesis I: PWY-7184
    • 9 reactions found over NA reactions in the full pathway
  • PWY-7199, pyrimidine deoxyribonucleosides salvage: PWY-7199
    • 2 reactions found over NA reactions in the full pathway
  • PWY-7198, pyrimidine deoxyribonucleotides de novo biosynthesis IV: PWY-7198
    • 6 reactions found over NA reactions in the full pathway
  • PWY-7210, pyrimidine deoxyribonucleotides biosynthesis from CTP: PWY-7210
    • 6 reactions found over NA reactions in the full pathway

Reconstruction information

External links





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