Difference between revisions of "3-ISOPROPYLMALISOM-RXN"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-14789 RXN-14789] == * common name: ** fatty acyl-CoA oxidase * ec number: ** [http://enzyme.exp...")
 
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=3-ISOPROPYLMALISOM-RXN 3-ISOPROPYLMALISOM-RXN] == * common name: ** 3-isopropylmalate dehydratase *...")
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-14789 RXN-14789] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=3-ISOPROPYLMALISOM-RXN 3-ISOPROPYLMALISOM-RXN] ==
 
* common name:
 
* common name:
** fatty acyl-CoA oxidase
+
** 3-isopropylmalate dehydratase
* ec number:
 
** [http://enzyme.expasy.org/EC/1.3.3.6 EC-1.3.3.6]
 
 
* direction:
 
* direction:
** LEFT-TO-RIGHT
+
** REVERSIBLE
 
* Synonym(s):
 
* Synonym(s):
 +
** (2R,3S)-3-isopropylmalate hydro-lyase
 +
** β-isopropylmalate dehydratase
 +
** α-isopropylmalate isomerase
 +
** 3-isopropylmalate hydro-lyase
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
** 1 [[CPD-15677]][c] '''+''' 1 [[OXYGEN-MOLECULE]][c] '''=>''' 1 [[CPD-15661]][c] '''+''' 1 [[HYDROGEN-PEROXIDE]][c]
+
** 1 [[CPD-9451]][c] '''+''' 1 [[WATER]][c] '''<=>''' 1 [[3-CARBOXY-3-HYDROXY-ISOCAPROATE]][c]
 
* With common name(s):
 
* With common name(s):
** 1 4-trans-undecenoyl-CoA[c] '''+''' 1 oxygen[c] '''=>''' 1 2-trans, 4-trans-undecadienoyl-CoA[c] '''+''' 1 hydrogen peroxide[c]
+
** 1 2-isopropylmaleate[c] '''+''' 1 H2O[c] '''<=>''' 1 (2S)-2-isopropylmalate[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
* Gene: [[DN19232_c0_g1_i2]]
+
* Gene: [[DN18105_c0_g1_i1]]
 
** Source: [[annotation-transcriptome]]
 
** Source: [[annotation-transcriptome]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
* Gene: [[DN13602_c0_g1_i2]]
+
* Gene: [[DN22072_c0_g1_i1]]
** Source: [[annotation-transcriptome]]
 
*** Assignment: EC-NUMBER
 
* Gene: [[DN17066_c0_g1_i1]]
 
 
** Source: [[annotation-transcriptome]]
 
** Source: [[annotation-transcriptome]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
 
== Pathways  ==
 
== Pathways  ==
* [[PWY-7338]], 10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7338 PWY-7338]
+
* [[PWY-6871]], 3-methylbutanol biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6871 PWY-6871]
** '''3''' reactions found over '''NA''' reactions in the full pathway
+
** '''4''' reactions found over '''NA''' reactions in the full pathway
 +
* [[LEUSYN-PWY]], L-leucine biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=LEUSYN-PWY LEUSYN-PWY]
 +
** '''5''' reactions found over '''NA''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 
* Category: [[annotation]]
 
* Category: [[annotation]]
Line 34: Line 35:
 
*** Tool: [[pathwaytools]]
 
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
{{#set: common name=fatty acyl-CoA oxidase}}
+
* RHEA:
{{#set: ec number=EC-1.3.3.6}}
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=16296 16296]
{{#set: direction=LEFT-TO-RIGHT}}
+
* LIGAND-RXN:
{{#set: gene associated=DN19232_c0_g1_i2|DN13602_c0_g1_i2|DN17066_c0_g1_i1}}
+
** [http://www.genome.jp/dbget-bin/www_bget?R03968 R03968]
{{#set: in pathway=PWY-7338}}
+
* UNIPROT:
 +
** [http://www.uniprot.org/uniprot/Q9PLW1 Q9PLW1]
 +
** [http://www.uniprot.org/uniprot/Q9JU82 Q9JU82]
 +
** [http://www.uniprot.org/uniprot/P80858 P80858]
 +
** [http://www.uniprot.org/uniprot/Q9UZ07 Q9UZ07]
 +
** [http://www.uniprot.org/uniprot/Q9JU81 Q9JU81]
 +
** [http://www.uniprot.org/uniprot/Q58673 Q58673]
 +
** [http://www.uniprot.org/uniprot/Q02144 Q02144]
 +
** [http://www.uniprot.org/uniprot/P44968 P44968]
 +
** [http://www.uniprot.org/uniprot/Q58667 Q58667]
 +
** [http://www.uniprot.org/uniprot/P44438 P44438]
 +
** [http://www.uniprot.org/uniprot/P0A6A6 P0A6A6]
 +
** [http://www.uniprot.org/uniprot/Q9PLW2 Q9PLW2]
 +
** [http://www.uniprot.org/uniprot/Q44022 Q44022]
 +
** [http://www.uniprot.org/uniprot/Q44023 Q44023]
 +
** [http://www.uniprot.org/uniprot/Q44427 Q44427]
 +
** [http://www.uniprot.org/uniprot/P17279 P17279]
 +
** [http://www.uniprot.org/uniprot/P04787 P04787]
 +
** [http://www.uniprot.org/uniprot/P15717 P15717]
 +
** [http://www.uniprot.org/uniprot/P18250 P18250]
 +
** [http://www.uniprot.org/uniprot/Q02142 Q02142]
 +
** [http://www.uniprot.org/uniprot/P30126 P30126]
 +
** [http://www.uniprot.org/uniprot/P50181 P50181]
 +
** [http://www.uniprot.org/uniprot/P07264 P07264]
 +
** [http://www.uniprot.org/uniprot/P74207 P74207]
 +
** [http://www.uniprot.org/uniprot/O86534 O86534]
 +
** [http://www.uniprot.org/uniprot/O86535 O86535]
 +
{{#set: common name=3-isopropylmalate dehydratase}}
 +
{{#set: direction=REVERSIBLE}}
 +
{{#set: common name=(2R,3S)-3-isopropylmalate hydro-lyase|&beta;-isopropylmalate dehydratase|&alpha;-isopropylmalate isomerase|3-isopropylmalate hydro-lyase}}
 +
{{#set: gene associated=DN18105_c0_g1_i1|DN22072_c0_g1_i1}}
 +
{{#set: in pathway=PWY-6871|LEUSYN-PWY}}
 
{{#set: reconstruction category=annotation}}
 
{{#set: reconstruction category=annotation}}
 
{{#set: reconstruction source=annotation-transcriptome}}
 
{{#set: reconstruction source=annotation-transcriptome}}
 
{{#set: reconstruction tool=pathwaytools}}
 
{{#set: reconstruction tool=pathwaytools}}

Latest revision as of 14:21, 15 January 2021

Reaction 3-ISOPROPYLMALISOM-RXN

  • common name:
    • 3-isopropylmalate dehydratase
  • direction:
    • REVERSIBLE
  • Synonym(s):
    • (2R,3S)-3-isopropylmalate hydro-lyase
    • β-isopropylmalate dehydratase
    • α-isopropylmalate isomerase
    • 3-isopropylmalate hydro-lyase

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-6871, 3-methylbutanol biosynthesis (engineered): PWY-6871
    • 4 reactions found over NA reactions in the full pathway
  • LEUSYN-PWY, L-leucine biosynthesis: LEUSYN-PWY
    • 5 reactions found over NA reactions in the full pathway

Reconstruction information

External links