Difference between revisions of "RXN-7719"

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(Created page with "Category:reaction == Reaction RXN-8991 == * direction: ** reversible * common-name: ** 3-isopropylmalate dehydratase ** aconitase/3-isopropylmalate dehydratase, swivel * s...")
(Created page with "Category:reaction == Reaction RXN-7719 == * direction: ** reversible * common-name: ** dihydrolipoamide dehydrogenase ** branched chain alpha-keto acid dehydrogenase e1 be...")
 
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[[Category:reaction]]
 
[[Category:reaction]]
== Reaction RXN-8991 ==
+
== Reaction RXN-7719 ==
 
* direction:
 
* direction:
 
** reversible
 
** reversible
 
* common-name:
 
* common-name:
** 3-isopropylmalate dehydratase
+
** dihydrolipoamide dehydrogenase
** aconitase/3-isopropylmalate dehydratase, swivel
+
** branched chain alpha-keto acid dehydrogenase e1 beta subunit
* synonymous:
+
* ec-number:
** β-isopropylmalate dehydratase
+
** [http://enzyme.expasy.org/EC/1.8.1.4 ec-1.8.1.4]
** α-isopropylmalate isomerase
 
** (2r,3s)-3-isopropylmalate hydro-lyase
 
** 3-isopropylmalate hydro-lyase
 
 
== Reaction formula ==
 
== Reaction formula ==
* 1 [[2-D-THREO-HYDROXY-3-CARBOXY-ISOCAPROATE]][c] '''<=>''' 1 [[CPD-9451]][c] '''+''' 1 [[WATER]][c]
+
* 1 [[BCAA-dehydrogenase-DH-lipoyl]][c] '''+''' 1 [[NAD]][c] '''<=>''' 1 [[BCAA-dehydrogenase-lipoyl]][c] '''+''' 1 [[NADH]][c] '''+''' 1 [[PROTON]][c]
 
== Gene(s) associated with this reaction  ==
 
== Gene(s) associated with this reaction  ==
* Gene: [[Ec-13_001950]]
+
* Gene: [[Ec-06_009010]]
** Category: [[orthology]]
+
** Category: [[annotation]]
*** Source: [[output_pantograph_aragem]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
+
*** Source: [[esiliculosus_genome]], Tool: [[pathwaytools]], Assignment: automated-name-match, Comment: n.a
* Gene: [[Ec-12_000170]]
+
* Gene: [[Ec-27_004160]]
 +
** Category: [[annotation]]
 +
*** Source: [[esiliculosus_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 +
* Gene: [[Ec-25_000020]]
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[esiliculosus_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
*** Source: [[esiliculosus_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
** Category: [[orthology]]
 
*** Source: [[output_pantograph_aragem]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
* Gene: [[Ec-sdr_f_000030]]
 
** Category: [[orthology]]
 
*** Source: [[output_pantograph_aragem]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
 
== Pathway(s)  ==
 
== Pathway(s)  ==
* [[PWY-6871]], 3-methylbutanol biosynthesis (engineered):
+
* [[PWY-5046]], 2-oxoisovalerate decarboxylation to isobutanoyl-CoA:
** '''5''' reactions found over '''7''' reactions in the full pathway
+
** '''3''' reactions found over '''3''' reactions in the full pathway
* [[LEUSYN-PWY]], L-leucine biosynthesis:
 
** '''6''' reactions found over '''6''' reactions in the full pathway
 
 
== Reconstruction information  ==
 
== Reconstruction information  ==
* category: [[orthology]]; source: [[output_pantograph_aragem]]; tool: [[pantograph]]; comment: n.a
 
 
* category: [[annotation]]; source: [[esiliculosus_genome]]; tool: [[pathwaytools]]; comment: n.a
 
* category: [[annotation]]; source: [[esiliculosus_genome]]; tool: [[pathwaytools]]; comment: n.a
 
== External links  ==
 
== External links  ==
* METANETX-RXN : MNXR100827
+
* METANETX-RXN : MNXR122012
* RHEA:
 
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=10676 10676]
 
* LIGAND-RXN:
 
** [http://www.genome.jp/dbget-bin/www_bget?R04001 R04001]
 
 
{{#set: direction=reversible}}
 
{{#set: direction=reversible}}
{{#set: common-name=3-isopropylmalate dehydratase|aconitase/3-isopropylmalate dehydratase, swivel}}
+
{{#set: common-name=dihydrolipoamide dehydrogenase|branched chain alpha-keto acid dehydrogenase e1 beta subunit}}
{{#set: synonymous=&beta;-isopropylmalate dehydratase|&alpha;-isopropylmalate isomerase|3-isopropylmalate hydro-lyase|(2r,3s)-3-isopropylmalate hydro-lyase}}
+
{{#set: ec-number=ec-1.8.1.4}}
 
{{#set: nb gene associated=3}}
 
{{#set: nb gene associated=3}}
{{#set: nb pathway associated=2}}
+
{{#set: nb pathway associated=1}}
{{#set: reconstruction category=annotation|orthology}}
+
{{#set: reconstruction category=annotation}}
{{#set: reconstruction tool=pantograph|pathwaytools}}
+
{{#set: reconstruction tool=pathwaytools}}
 
{{#set: reconstruction comment=n.a}}
 
{{#set: reconstruction comment=n.a}}
{{#set: reconstruction source=esiliculosus_genome|output_pantograph_aragem}}
+
{{#set: reconstruction source=esiliculosus_genome}}

Latest revision as of 09:03, 18 March 2021

Reaction RXN-7719

  • direction:
    • reversible
  • common-name:
    • dihydrolipoamide dehydrogenase
    • branched chain alpha-keto acid dehydrogenase e1 beta subunit
  • ec-number:

Reaction formula

Gene(s) associated with this reaction

Pathway(s)

  • PWY-5046, 2-oxoisovalerate decarboxylation to isobutanoyl-CoA:
    • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

External links

  • METANETX-RXN : MNXR122012