1.14.11.2-RXN

Reaction 1.14.11.2-RXN

• common name:
  • prolyl 4-hydroxylase
• ec number:
  • EC-1.14.11.2
• direction:
  • LEFT-TO-RIGHT
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 PROCOLLAGEN-L-PROLINE[c] + 1 2-KETOGLUTARATE[c] + 1 OXYGEN-MOLECULE[c] => 1 CPD-6321[c] + 1 SUC[c] + 1 CARBON-DIOXIDE[c]
• With common name(s):
  • 1 a [procollagen]-L-proline[c] + 1 2-oxoglutarate[c] + 1 oxygen[c] => 1 a [procollagen] trans 4-hyroxy-L-proline[c] + 1 succinate[c] + 1 CO2[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: DN21786_c0_g1_i2
  • Source: annotation-transcriptome
    • Assignment: EC-NUMBER
• Gene: DN19566_c0_g1_i3
  • Source: annotation-transcriptome
    • Assignment: EC-NUMBER
• Gene: DN11040_c0_g1_i1
  • Source: annotation-transcriptome
    • Assignment: EC-NUMBER
• Gene: DN21786_c0_g1_i1
  • Source: annotation-transcriptome
    • Assignment: EC-NUMBER
• Gene: DN19566_c0_g1_i1
  • Source: annotation-transcriptome
    • Assignment: EC-NUMBER
• Gene: DN16449_c0_g1_i1
  • Source: annotation-transcriptome
    • Assignment: EC-NUMBER

Pathways

• PWY-7894, procollagen hydroxylation and glycosylation: PWY-7894
  • 1 reactions found over NA reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-transcriptome
    • Tool: pathwaytools

External links

• RHEA:
  • 18946
• LIGAND-RXN:
  • R03219
• UNIPROT:
  • P21195
  • Q10576
  • P16924
  • P13674
  • P05307
  • P09102
  • P07237
  • Q922C8
  • P04785
  • P54001