RXN-8661

Reaction RXN-8661

• common name:
  • [histone-H3]-lysine-36 demethylase
• ec number:
  • EC-1.14.11
• direction:
  • LEFT-TO-RIGHT
• Synonym(s):
  • JHDM1A
  • JmjC domain-containing histone demethylase 1A
  • H3-K36-specific demethylase
  • histone-lysine (H3-K36) demethylase
  • histone demethylase
  • protein-6-N,6-N-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase

Reaction Formula

• With identifiers:
  • 1 CPD-8901[c] + 1 2-KETOGLUTARATE[c] + 1 OXYGEN-MOLECULE[c] + 1 PROTON[c] => 1 Protein-L-lysine[c] + 1 SUC[c] + 1 FORMALDEHYDE[c] + 1 CARBON-DIOXIDE[c]
• With common name(s):
  • 1 a [protein] N6-methyl-L-lysine[c] + 1 2-oxoglutarate[c] + 1 oxygen[c] + 1 H+[c] => 1 a [protein]-L-lysine[c] + 1 succinate[c] + 1 formaldehyde[c] + 1 CO2[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: DN21730_c0_g1_i2
  • Source: annotation-transcriptome
    • Assignment: EC-NUMBER

Reconstruction information

• Category: annotation
  • Source: annotation-transcriptome
    • Tool: pathwaytools

External links

• RHEA:
  • 10785

Property "Common name" (as page type) with input value "histone-H3]-lysine-36 demethylase" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.