UBIQUITIN--PROTEIN-LIGASE-RXN

Reaction UBIQUITIN--PROTEIN-LIGASE-RXN

• direction:
  • left-to-right
• common-name:
  • ubiquitin-protein transferase
  • ubiquitin-activating enzyme e1, c-terminal
  • putative ubiquitin activating enzyme
  • ubiquitin activating enzyme (e1) subunit uba3
• ec-number:
  • ec-6.2.1.45

Reaction formula

• 1 ATP[c] + 1 Ubiquitin-C-Terminal-Glycine[c] + 1 Ubiquitin-activating-protein-E1-L-cys[c] => 1 AMP[c] + 1 PPI[c] + 1 S-ubiquitinyl-UAP-E1-L-cysteine[c]

Gene(s) associated with this reaction

• Gene: Ec-09_004750
  • Category: annotation
    • Source: esiliculosus_genome, Tool: pathwaytools, Assignment: ec-number, Comment: n.a
• Gene: Ec-13_002660
  • Category: annotation
    • Source: esiliculosus_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: Ec-01_007490
  • Category: annotation
    • Source: esiliculosus_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: Ec-26_001140
  • Category: annotation
    • Source: esiliculosus_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: Ec-22_002200
  • Category: annotation
    • Source: esiliculosus_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: Ec-01_008900
  • Category: annotation
    • Source: esiliculosus_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: Ec-01_009550
  • Category: annotation
    • Source: esiliculosus_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: Ec-06_002450
  • Category: annotation
    • Source: esiliculosus_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: Ec-25_000510
  • Category: annotation
    • Source: esiliculosus_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: Ec-25_002490
  • Category: annotation
    • Source: esiliculosus_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: Ec-18_001830
  • Category: annotation
    • Source: esiliculosus_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: Ec-01_001660
  • Category: annotation
    • Source: esiliculosus_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: Ec-14_006720
  • Category: annotation
    • Source: esiliculosus_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: Ec-25_000920
  • Category: annotation
    • Source: esiliculosus_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: Ec-14_003730
  • Category: annotation
    • Source: esiliculosus_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: Ec-00_007160
  • Category: annotation
    • Source: esiliculosus_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: Ec-25_000910
  • Category: annotation
    • Source: esiliculosus_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: Ec-09_000720
  • Category: annotation
    • Source: esiliculosus_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: Ec-14_001990
  • Category: annotation
    • Source: esiliculosus_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: Ec-25_002630
  • Category: annotation
    • Source: esiliculosus_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: Ec-27_002840
  • Category: annotation
    • Source: esiliculosus_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: Ec-01_010570
  • Category: annotation
    • Source: esiliculosus_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: Ec-16_001360
  • Category: annotation
    • Source: esiliculosus_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: Ec-24_003940
  • Category: annotation
    • Source: esiliculosus_genome, Tool: pathwaytools, Assignment: automated-name-match, Comment: n.a
• Gene: Ec-12_000320
  • Category: annotation
    • Source: esiliculosus_genome, Tool: pathwaytools, Assignment: automated-name-match, Comment: n.a

Pathway(s)

• PWY-7511, protein ubiquitination:
  • 9 reactions found over 9 reactions in the full pathway

Reconstruction information

• category: annotation; source: esiliculosus_genome; tool: pathwaytools; comment: n.a

External links

• METANETX-RXN : MNXR124084
• LIGAND-RXN:
  • R03876
• UNIPROT:
  • P22314
  • P49459
  • P62256
  • P63146
  • P28263
  • Q02053
  • P62257
  • P61088
  • P63279
  • P19812
  • P21734
  • P25869
  • P31254
  • P15731
  • P15732
  • P29340
  • P35133
  • P35134
  • P35132
  • P33296
  • P22515
  • P39940
  • P42748
  • P42750
  • P42749
  • P42747
  • P50623
  • Q42973
  • P40984
  • Q92462
  • Q42540
  • P93028
  • P93393
  • P31252
  • P52486
  • Q9YGM6
  • O42646
  • O15979
  • P23566
  • Q96PU5
  • P27949