CITSYN-RXN

Reaction CITSYN-RXN

• direction:
  • LEFT-TO-RIGHT
• ec number:
  • EC-2.3.3.16
  • EC-2.3.3.1
• Synonym(s):
  • Condensing enzyme
  • citrate synthesis

Reaction Formula

• With identifiers:
  • 1 WATER[c] + 1 ACETYL-COA[c] + 1 OXALACETIC_ACID[c] => 1 CIT[c] + 1 CO-A[c] + 1 PROTON[c]
• With common name(s):
  • 1 H2O[c] + 1 acetyl-CoA[c] + 1 oxaloacetate[c] => 1 citrate[c] + 1 coenzyme A[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: CHC_T00007817001_1
  • Source: orthology-galdieria.sulphuraria

Pathways

• FERMENTATION-PWY, mixed acid fermentation: FERMENTATION-PWY
  • 11 reactions found over 16 reactions in the full pathway
• PWY-5690, TCA cycle II (plants and fungi): PWY-5690
  • 9 reactions found over 9 reactions in the full pathway
• PWY-5750, itaconate biosynthesis: PWY-5750
  • 3 reactions found over 4 reactions in the full pathway
• PWY-7254, TCA cycle VII (acetate-producers): PWY-7254
  • 7 reactions found over 9 reactions in the full pathway
• GLYOXYLATE-BYPASS, glyoxylate cycle: GLYOXYLATE-BYPASS
  • 4 reactions found over 6 reactions in the full pathway
• PWY-7124, ethylene biosynthesis V (engineered): PWY-7124
  • 8 reactions found over 10 reactions in the full pathway
• P105-PWY, TCA cycle IV (2-oxoglutarate decarboxylase): P105-PWY
  • 8 reactions found over 11 reactions in the full pathway
• PWY-5913, partial TCA cycle (obligate autotrophs): PWY-5913
  • 10 reactions found over 11 reactions in the full pathway
• TCA, TCA cycle I (prokaryotic): TCA
  • 9 reactions found over 10 reactions in the full pathway
• PWY-6728, methylaspartate cycle: PWY-6728
  • 9 reactions found over 19 reactions in the full pathway
• PWY66-398, TCA cycle III (animals): PWY66-398
  • 11 reactions found over 11 reactions in the full pathway
• PWY-6549, L-glutamine biosynthesis III: PWY-6549
  • 9 reactions found over 9 reactions in the full pathway
• PWY-6969, TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase): PWY-6969
  • 8 reactions found over 12 reactions in the full pathway
• REDCITCYC, TCA cycle VIII (helicobacter): REDCITCYC
  • 5 reactions found over 9 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-galdieria.sulphuraria
    • Tool: pantograph

External links

• RHEA:
  • 16845
• UNIPROT:
  • Q9JRA5
  • Q9JQX0
  • P31660
  • Q9CHQ6
  • P39120
  • Q9PLZ5
  • P20902
  • P51033
  • P39119
  • P42457
  • P18789
  • P20903
  • P51038
  • P34085
  • P34575
  • Q43175
  • P43635
  • O24259
  • O32705
  • P00890
  • P08679
  • P0ABH7
  • Q47237
  • P20115
  • P26491
  • P00889
  • P20901
  • P09948
  • P21553
• PIR:
  • A43936
  • A81200
  • B81139
  • E64760
  • F86708
  • G69600
  • G81265
  • I39506
  • I40044
  • I40380
  • I40717
  • JQ1392
  • PQ0046
  • S41527
  • S41563
  • S42370
  • S44316
  • S52814
  • T02390
  • T09334
  • T44615
  • YKBY
  • YKBYC
  • YKEC
  • YKMUM
  • YKMY
  • YKPG
  • YKPSCA
  • YKQPC
  • YKRECP
  • YKYT
• LIGAND-RXN:
  • R00351