PYRUVDEH-RXN

Reaction PYRUVDEH-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • pyruvate dehydrogenase E1 alpha subunit, mitochondrial precursor
• ec number:
  • EC-1.2.1
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 NAD[c] + 1 PYRUVATE[c] + 1 CO-A[c] => 1 NADH[c] + 1 ACETYL-COA[c] + 1 CARBON-DIOXIDE[c]
• With common name(s):
  • 1 NAD+[c] + 1 pyruvate[c] + 1 coenzyme A[c] => 1 NADH[c] + 1 acetyl-CoA[c] + 1 CO2[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: CHC_T00010287001_1
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-arabidopsis_thaliana
  • Source: orthology-arabidopsis_thaliana
• Gene: CHC_T00008732001_1
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-arabidopsis_thaliana
• Gene: CHC_T00008442001_1
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-arabidopsis_thaliana
• Gene: CHC_T00008441001_1
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-arabidopsis_thaliana
  • Source: orthology-arabidopsis_thaliana
• Gene: CHC_T00008732001
  • Source: annotation-original_genome
    • Assignment: AUTOMATED-NAME-MATCH
• Gene: CHC_T00007488001_1
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-arabidopsis_thaliana
  • Source: orthology-arabidopsis_thaliana
• Gene: CHC_T00007380001_1
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-arabidopsis_thaliana
  • Source: orthology-arabidopsis_thaliana

Pathways

• PWY-7384, anaerobic energy metabolism (invertebrates, mitochondrial): PWY-7384
  • 5 reactions found over 12 reactions in the full pathway
• PWY-5537, pyruvate fermentation to acetate V: PWY-5537
  • 2 reactions found over 4 reactions in the full pathway
• GLYCOLYSIS-TCA-GLYOX-BYPASS, superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass: GLYCOLYSIS-TCA-GLYOX-BYPASS
  • 3 reactions found over 5 reactions in the full pathway
• PWY-7218, photosynthetic 3-hydroxybutanoate biosynthesis (engineered): PWY-7218
  • 7 reactions found over 10 reactions in the full pathway
• PWY-5482, pyruvate fermentation to acetate II: PWY-5482
  • 1 reactions found over 3 reactions in the full pathway
• PWY-6886, 1-butanol autotrophic biosynthesis (engineered): PWY-6886
  • 8 reactions found over 11 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-arabidopsis_thaliana
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-original_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 28042
• LIGAND-RXN:
  • R00209