Difference between revisions of "PHOSPHOMEVALONATE-KINASE-RXN"

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(Created page with "Category:reaction == Reaction 4.2.1.58-RXN == <div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;"> * direction: ** left-to-right * commo...")
(Created page with "Category:reaction == Reaction PHOSPHOMEVALONATE-KINASE-RXN == * direction: ** reversible * common-name: ** phosphomevalonate kinase * ec-number: ** [http://enzyme.expasy.o...")
 
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[[Category:reaction]]
 
[[Category:reaction]]
−
== Reaction 4.2.1.58-RXN ==
+
== Reaction PHOSPHOMEVALONATE-KINASE-RXN ==
−
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
 
 
* direction:
 
* direction:
−
** left-to-right
+
** reversible
 
* common-name:
 
* common-name:
−
** (3r)-3-hydroxybutanoyl-[acyl-carrier-protein] hydratase
+
** phosphomevalonate kinase
−
** fatty acid synthase
 
−
** (3r)-3-hydroxybutanoyl-[acyl-carrier protein] dehydratase
 
 
* ec-number:
 
* ec-number:
−
** [http://enzyme.expasy.org/EC/2.3.1.86 ec-2.3.1.86]
+
** [http://enzyme.expasy.org/EC/2.7.4.2 ec-2.7.4.2]
−
** [http://enzyme.expasy.org/EC/2.3.1.85 ec-2.3.1.85]
 
−
** [http://enzyme.expasy.org/EC/4.2.1.59 ec-4.2.1.59]
 
−
* synonymous:
 
−
** (3r)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase (but-2-enoyl-[acyl-carrier protein]-forming)
 
−
** crotonoyl-[acyl-carrier-protein] hydratase
 
−
** &beta;-hydroxybutyryl acyl carrier protein dehydrase
 
−
** 3-hydroxybutyryl acyl carrier protein dehydratase
 
−
** enoyl acyl carrier protein hydrase
 
−
** (3r)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase
 
−
** crotonyl acyl carrier protein hydratase
 
−
** &beta;-hydroxybutyryl acyl carrier protein (acp) dehydrase
 
−
** &beta;-hydroxybutyryl acyl carrier  protein dehydrase
 
−
</div>
 
 
== Reaction formula ==
 
== Reaction formula ==
−
* 1 [[Beta-3-hydroxybutyryl-ACPs]][c] '''=>''' 1 [[Crotonyl-ACPs]][c] '''+''' 1 [[WATER]][c]
+
* 1 [[ATP]][c] '''+''' 1 [[CPD-499]][c] '''<=>''' 1 [[ADP]][c] '''+''' 1 [[CPD-641]][c]
 
== Gene(s) associated with this reaction  ==
 
== Gene(s) associated with this reaction  ==
−
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
+
* Gene: [[SJ04742]]
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* Gene: [[SJ11672]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ19629]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ00320]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ04443]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ10624]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ15983]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ17743]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ10275]]
 
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
−
* Gene: [[SJ03883]]
+
** Category: [[orthology]]
−
** Category: [[annotation]]
+
*** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
+
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
−
* Gene: [[SJ00613]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ13014]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ06617]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ18059]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ06616]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ06944]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ04769]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
</div>
 
 
== Pathway(s)  ==
 
== Pathway(s)  ==
−
* [[PWY-5971]], palmitate biosynthesis II (bacteria and plant cytoplasm):
+
* [[PWY-7391]], isoprene biosynthesis II (engineered):
−
** '''31''' reactions found over '''31''' reactions in the full pathway
+
** '''7''' reactions found over '''8''' reactions in the full pathway
−
* [[PWY-5994]], palmitate biosynthesis (animals and fungi, cytoplasm):
+
* [[PWY-922]], mevalonate pathway I (eukaryotes and bacteria):
−
** '''31''' reactions found over '''31''' reactions in the full pathway
+
** '''7''' reactions found over '''7''' reactions in the full pathway
−
* [[PWY-7388]], octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast):
 
−
** '''7''' reactions found over '''11''' reactions in the full pathway
 
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 +
* category: [[orthology]]; source: [[output_pantograph_arabidopsis_thaliana]]; tool: [[pantograph]]; comment: n.a
 +
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
 
== External links  ==
 
== External links  ==
 +
* METANETX-RXN : MNXR103043
 +
* RHEA:
 +
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=16344 16344]
 
* LIGAND-RXN:
 
* LIGAND-RXN:
−
** [http://www.genome.jp/dbget-bin/www_bget?R04428 R04428]
+
** [http://www.genome.jp/dbget-bin/www_bget?R03245 R03245]
−
{{#set: direction=left-to-right}}
+
* UNIPROT:
−
{{#set: common-name=(3r)-3-hydroxybutanoyl-[acyl-carrier-protein] hydratase|fatty acid synthase|(3r)-3-hydroxybutanoyl-[acyl-carrier protein] dehydratase}}
+
** [http://www.uniprot.org/uniprot/P24521 P24521]
−
{{#set: ec-number=ec-4.2.1.59|ec-2.3.1.86|ec-2.3.1.85}}
+
{{#set: direction=reversible}}
−
{{#set: synonymous=&beta;-hydroxybutyryl acyl carrier protein (acp) dehydrase|crotonoyl-[acyl-carrier-protein] hydratase|&beta;-hydroxybutyryl acyl carrier  protein dehydrase|3-hydroxybutyryl acyl carrier protein dehydratase|(3r)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase (but-2-enoyl-[acyl-carrier protein]-forming)|enoyl acyl carrier protein hydrase|(3r)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase|&beta;-hydroxybutyryl acyl carrier protein dehydrase|crotonyl acyl carrier protein hydratase}}
+
{{#set: common-name=phosphomevalonate kinase}}
−
{{#set: nb gene associated=16}}
+
{{#set: ec-number=ec-2.7.4.2}}
−
{{#set: nb pathway associated=3}}
+
{{#set: nb gene associated=1}}
−
{{#set: reconstruction category=annotation}}
+
{{#set: nb pathway associated=2}}
−
{{#set: reconstruction tool=pathwaytools}}
+
{{#set: reconstruction category=orthology|annotation}}
 +
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
{{#set: reconstruction comment=n.a}}
 
{{#set: reconstruction comment=n.a}}
−
{{#set: reconstruction source=saccharina_japonica_genome}}
+
{{#set: reconstruction source=output_pantograph_ectocarpus_siliculosus|output_pantograph_arabidopsis_thaliana|saccharina_japonica_genome}}

Latest revision as of 11:20, 18 March 2021

Reaction PHOSPHOMEVALONATE-KINASE-RXN

  • direction:
    • reversible
  • common-name:
    • phosphomevalonate kinase
  • ec-number:

Reaction formula

Gene(s) associated with this reaction

Pathway(s)

  • PWY-7391, isoprene biosynthesis II (engineered):
    • 7 reactions found over 8 reactions in the full pathway
  • PWY-922, mevalonate pathway I (eukaryotes and bacteria):
    • 7 reactions found over 7 reactions in the full pathway

Reconstruction information

External links





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