Difference between revisions of "RXN66-305"

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(Created page with "Category:reaction == Reaction RXN-12567 == * direction: ** left-to-right * common-name: ** enoyl-coa hydratase ** 3-hydroxyhexanoyl-coa dehydratase * ec-number: ** [http:/...")
(Created page with "Category:reaction == Reaction RXN66-305 == * direction: ** left-to-right * common-name: ** 14-oxolanosterol deformylase ** 4,4-dimethyl-14α-formyl-5α-cholesta-...")
 
(5 intermediate revisions by 3 users not shown)
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[[Category:reaction]]
 
[[Category:reaction]]
−
== Reaction RXN-12567 ==
+
== Reaction RXN66-305 ==
 
* direction:
 
* direction:
 
** left-to-right
 
** left-to-right
 
* common-name:
 
* common-name:
−
** enoyl-coa hydratase
+
** 14-oxolanosterol deformylase
−
** 3-hydroxyhexanoyl-coa dehydratase
+
** 4,4-dimethyl-14α-formyl-5α-cholesta-8,24-dien-3β-ol,nadph:oxygen oxidoreductase (14-methyl cleaving)
−
* ec-number:
 
−
** [http://enzyme.expasy.org/EC/4.2.1.17 ec-4.2.1.17]
 
 
== Reaction formula ==
 
== Reaction formula ==
−
* 1 [[OH-HEXANOYL-COA]][c] '''=>''' 1 [[CPD0-2121]][c] '''+''' 1 [[WATER]][c]
+
* 1 [[CPD-4573]][c] '''+''' 1 [[NADPH]][c] '''+''' 1 [[OXYGEN-MOLECULE]][c] '''=>''' 1 [[44-DIMETHYL-CHOLESTA-814-24-TRIENOL]][c] '''+''' 1 [[FORMATE]][c] '''+''' 1 [[NADP]][c] '''+''' 1 [[WATER]][c]
 
== Gene(s) associated with this reaction  ==
 
== Gene(s) associated with this reaction  ==
−
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
+
* Gene: [[SJ05072]]
−
* Gene: [[SJ00040]]
 
−
** Category: [[orthology]]
 
−
*** Source: [[output_pantograph_nannochloropsis_salina]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
−
* Gene: [[SJ03913]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
−
** Category: [[orthology]]
 
−
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
−
* Gene: [[SJ03584]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
** Category: [[orthology]]
 
−
*** Source: [[output_pantograph_nannochloropsis_salina]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
−
* Gene: [[SJ10275]]
 
−
** Category: [[orthology]]
 
−
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
−
* Gene: [[SJ21390]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
−
** Category: [[orthology]]
 
−
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
−
* Gene: [[SJ07211]]
 
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
** Category: [[orthology]]
 
** Category: [[orthology]]
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
−
* Gene: [[SJ14591]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
</div>
 
 
== Pathway(s)  ==
 
== Pathway(s)  ==
−
* [[PWY-6863]], pyruvate fermentation to hexanol (engineered):
+
* [[PWY66-341]], cholesterol biosynthesis I:
−
** '''9''' reactions found over '''11''' reactions in the full pathway
+
** '''14''' reactions found over '''18''' reactions in the full pathway
 +
* [[PWY66-4]], cholesterol biosynthesis III (via desmosterol):
 +
** '''14''' reactions found over '''4''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 +
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
−
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
 
−
* category: [[orthology]]; source: [[output_pantograph_nannochloropsis_salina]]; tool: [[pantograph]]; comment: n.a
 
 
== External links  ==
 
== External links  ==
−
* RHEA:
+
* METANETX-RXN : MNXR123709
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=30549 30549]
 
−
* LIGAND-RXN:
 
−
** [http://www.genome.jp/dbget-bin/www_bget?R04749 R04749]
 
 
{{#set: direction=left-to-right}}
 
{{#set: direction=left-to-right}}
−
{{#set: common-name=3-hydroxyhexanoyl-coa dehydratase|enoyl-coa hydratase}}
+
{{#set: common-name=14-oxolanosterol deformylase|4,4-dimethyl-14&alpha;-formyl-5&alpha;-cholesta-8,24-dien-3&beta;-ol,nadph:oxygen oxidoreductase (14-methyl cleaving)}}
−
{{#set: ec-number=ec-4.2.1.17}}
+
{{#set: nb gene associated=1}}
−
{{#set: nb gene associated=7}}
+
{{#set: nb pathway associated=2}}
−
{{#set: nb pathway associated=1}}
+
{{#set: reconstruction category=orthology|annotation}}
−
{{#set: reconstruction category=annotation|orthology}}
 
 
{{#set: reconstruction tool=pathwaytools|pantograph}}
 
{{#set: reconstruction tool=pathwaytools|pantograph}}
 
{{#set: reconstruction comment=n.a}}
 
{{#set: reconstruction comment=n.a}}
−
{{#set: reconstruction source=output_pantograph_nannochloropsis_salina|saccharina_japonica_genome|output_pantograph_ectocarpus_siliculosus}}
+
{{#set: reconstruction source=output_pantograph_ectocarpus_siliculosus|saccharina_japonica_genome}}

Latest revision as of 11:23, 18 March 2021

Reaction RXN66-305

  • direction:
    • left-to-right
  • common-name:
    • 14-oxolanosterol deformylase
    • 4,4-dimethyl-14α-formyl-5α-cholesta-8,24-dien-3β-ol,nadph:oxygen oxidoreductase (14-methyl cleaving)

Reaction formula

Gene(s) associated with this reaction

Pathway(s)

  • PWY66-341, cholesterol biosynthesis I:
    • 14 reactions found over 18 reactions in the full pathway
  • PWY66-4, cholesterol biosynthesis III (via desmosterol):
    • 14 reactions found over 4 reactions in the full pathway

Reconstruction information

External links

  • METANETX-RXN : MNXR123709





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