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| | [[Category:reaction]] | | [[Category:reaction]] |
| − | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=PYRUVDEH-RXN PYRUVDEH-RXN] == | + | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-14199 RXN-14199] == |
| | * direction: | | * direction: |
| | ** left-to-right | | ** left-to-right |
| − | * common-name:
| |
| − | ** pyruvate dehydrogenase (nad+)
| |
| | * ec-number: | | * ec-number: |
| − | ** [http://enzyme.expasy.org/EC/1.2.1 ec-1.2.1] | + | ** [http://enzyme.expasy.org/EC/3.6.1.5 ec-3.6.1.5] |
| | == Reaction formula == | | == Reaction formula == |
| − | * 1 [[CO-A]][c] '''+''' 1 [[NAD]][c] '''+''' 1 [[PYRUVATE]][c] '''=>''' 1 [[ACETYL-COA]][c] '''+''' 1 [[CARBON-DIOXIDE]][c] '''+''' 1 [[NADH]][c] | + | * 1 [[DUTP]][c] '''+''' 2 [[WATER]][c] '''=>''' 1 [[DUMP]][c] '''+''' 2 [[PROTON]][c] '''+''' 2 [[Pi]][c] |
| | == Gene(s) associated with this reaction == | | == Gene(s) associated with this reaction == |
| − | <div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
| + | * Gene: [[SJ16444]] |
| − | * Gene: [[SJ06474]] | |
| | ** Category: [[orthology]] | | ** Category: [[orthology]] |
| − | *** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
| |
| − | *** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
| |
| | *** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a | | *** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a |
| − | * Gene: [[SJ10087]]
| |
| − | ** Category: [[orthology]]
| |
| − | *** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
| |
| − | *** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
| |
| − | *** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
| |
| − | * Gene: [[SJ10725]]
| |
| − | ** Category: [[orthology]]
| |
| − | *** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
| |
| − | * Gene: [[SJ00971]]
| |
| − | ** Category: [[annotation]]
| |
| − | *** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
| |
| − | ** Category: [[orthology]]
| |
| − | *** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
| |
| − | *** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
| |
| − | *** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
| |
| − | * Gene: [[SJ01042]]
| |
| − | ** Category: [[annotation]]
| |
| − | *** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
| |
| − | * Gene: [[SJ19470]]
| |
| − | ** Category: [[orthology]]
| |
| − | *** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
| |
| − | *** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
| |
| − | * Gene: [[SJ13629]]
| |
| − | ** Category: [[orthology]]
| |
| − | *** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
| |
| − | *** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
| |
| − | *** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
| |
| − | * Gene: [[SJ09312]]
| |
| − | ** Category: [[orthology]]
| |
| − | *** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
| |
| − | * Gene: [[SJ14925]]
| |
| − | ** Category: [[orthology]]
| |
| − | *** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
| |
| − | *** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
| |
| − | </div>
| |
| | == Pathway(s) == | | == Pathway(s) == |
| − | * [[PWY-7384]], anaerobic energy metabolism (invertebrates, mitochondrial): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7384 PWY-7384]
| |
| − | ** '''6''' reactions found over '''10''' reactions in the full pathway
| |
| − | * [[GLYCOLYSIS-TCA-GLYOX-BYPASS]], superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass: [http://metacyc.org/META/NEW-IMAGE?object=GLYCOLYSIS-TCA-GLYOX-BYPASS GLYCOLYSIS-TCA-GLYOX-BYPASS]
| |
| − | ** '''3''' reactions found over '''1''' reactions in the full pathway
| |
| − | * [[PWY-7218]], photosynthetic 3-hydroxybutanoate biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7218 PWY-7218]
| |
| − | ** '''7''' reactions found over '''4''' reactions in the full pathway
| |
| − | * [[PWY-5482]], pyruvate fermentation to acetate II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5482 PWY-5482]
| |
| − | ** '''2''' reactions found over '''3''' reactions in the full pathway
| |
| − | * [[PWY-5537]], pyruvate fermentation to acetate V: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5537 PWY-5537]
| |
| − | ** '''2''' reactions found over '''2''' reactions in the full pathway
| |
| − | * [[PWY-6886]], 1-butanol autotrophic biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6886 PWY-6886]
| |
| − | ** '''8''' reactions found over '''5''' reactions in the full pathway
| |
| | == Reconstruction information == | | == Reconstruction information == |
| − | * category: [[orthology]]; source: [[output_pantograph_arabidopsis_thaliana]]; tool: [[pantograph]]; comment: n.a
| |
| | * category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a | | * category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a |
| − | * category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
| |
| | == External links == | | == External links == |
| − | * RHEA:
| |
| − | ** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=28042 28042]
| |
| − | * LIGAND-RXN:
| |
| − | ** [http://www.genome.jp/dbget-bin/www_bget?R00209 R00209]
| |
| | {{#set: direction=left-to-right}} | | {{#set: direction=left-to-right}} |
| − | {{#set: common-name=pyruvate dehydrogenase (nad+)}}
| + | {{#set: ec-number=ec-3.6.1.5}} |
| − | {{#set: ec-number=ec-1.2.1}} | + | {{#set: nb gene associated=1}} |
| − | {{#set: nb gene associated=9}} | + | {{#set: nb pathway associated=0}} |
| − | {{#set: nb pathway associated=6}} | + | {{#set: reconstruction category=orthology}} |
| − | {{#set: reconstruction category=orthology|annotation}} | + | {{#set: reconstruction tool=pantograph}} |
| − | {{#set: reconstruction tool=pantograph|pathwaytools}} | |
| | {{#set: reconstruction comment=n.a}} | | {{#set: reconstruction comment=n.a}} |
| − | {{#set: reconstruction source=output_pantograph_arabidopsis_thaliana|output_pantograph_ectocarpus_siliculosus|saccharina_japonica_genome}} | + | {{#set: reconstruction source=output_pantograph_ectocarpus_siliculosus}} |
