Difference between revisions of "4.2.1.58-RXN"

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(Created page with "Category:reaction == Reaction 2OXOGLUTDECARB-RXN == * direction: ** left-to-right * common-name: ** 2-oxoglutarate decarboxylase * ec-number: ** [http://enzyme.expasy.org/...")
(Created page with "Category:reaction == Reaction 4.2.1.58-RXN == <div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;"> * direction: ** left-to-right * commo...")
 
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[[Category:reaction]]
 
[[Category:reaction]]
−
== Reaction 2OXOGLUTDECARB-RXN ==
+
== Reaction 4.2.1.58-RXN ==
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
 
* direction:
 
* direction:
 
** left-to-right
 
** left-to-right
 
* common-name:
 
* common-name:
−
** 2-oxoglutarate decarboxylase
+
** (3r)-3-hydroxybutanoyl-[acyl-carrier-protein] hydratase
 +
** fatty acid synthase
 +
** (3r)-3-hydroxybutanoyl-[acyl-carrier protein] dehydratase
 
* ec-number:
 
* ec-number:
−
** [http://enzyme.expasy.org/EC/1.2.4.2 ec-1.2.4.2]
+
** [http://enzyme.expasy.org/EC/2.3.1.86 ec-2.3.1.86]
 +
** [http://enzyme.expasy.org/EC/2.3.1.85 ec-2.3.1.85]
 +
** [http://enzyme.expasy.org/EC/4.2.1.59 ec-4.2.1.59]
 
* synonymous:
 
* synonymous:
−
** oxoglutarate decarboxylase
+
** &beta;-hydroxybutyryl acyl carrier protein (acp) dehydrase
−
** 2-oxoglutarate decarboxylation
+
** 3-hydroxybutyryl acyl carrier protein dehydratase
 +
** crotonyl acyl carrier protein hydratase
 +
** enoyl acyl carrier protein hydrase
 +
** (3r)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase (but-2-enoyl-[acyl-carrier protein]-forming)
 +
** &beta;-hydroxybutyryl acyl carrier  protein dehydrase
 +
** (3r)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase
 +
** crotonoyl-[acyl-carrier-protein] hydratase
 +
** &beta;-hydroxybutyryl acyl carrier protein dehydrase
 +
</div>
 
== Reaction formula ==
 
== Reaction formula ==
−
* 1 [[2-KETOGLUTARATE]][c] '''+''' 1 [[Oxo-glutarate-dehydrogenase-lipoyl]][c] '''+''' 1 [[PROTON]][c] '''=>''' 1 [[CARBON-DIOXIDE]][c] '''+''' 1 [[Oxo-glutarate-dehydro-suc-DH-lipoyl]][c]
+
* 1 [[Beta-3-hydroxybutyryl-ACPs]][c] '''=>''' 1 [[Crotonyl-ACPs]][c] '''+''' 1 [[WATER]][c]
 
== Gene(s) associated with this reaction  ==
 
== Gene(s) associated with this reaction  ==
−
* Gene: [[SJ21701]]
+
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
 +
* Gene: [[SJ11672]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
* Gene: [[SJ19629]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
* Gene: [[SJ00320]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
* Gene: [[SJ04443]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
* Gene: [[SJ10624]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
* Gene: [[SJ15983]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
* Gene: [[SJ17743]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
* Gene: [[SJ10275]]
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
−
** Category: [[orthology]]
+
* Gene: [[SJ03883]]
−
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
+
** Category: [[annotation]]
−
* Gene: [[SJ13629]]
+
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
−
** Category: [[orthology]]
+
* Gene: [[SJ00613]]
−
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
+
** Category: [[annotation]]
−
* Gene: [[SJ06474]]
+
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
−
** Category: [[orthology]]
+
* Gene: [[SJ13014]]
−
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
+
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
* Gene: [[SJ06617]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
* Gene: [[SJ18059]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
* Gene: [[SJ06616]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
* Gene: [[SJ06944]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
* Gene: [[SJ04769]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
</div>
 
== Pathway(s)  ==
 
== Pathway(s)  ==
−
* [[PWY66-398]], TCA cycle III (animals):
+
* [[PWY-5971]], palmitate biosynthesis (type II fatty acid synthase):
−
** '''10''' reactions found over '''10''' reactions in the full pathway
+
** '''31''' reactions found over '''31''' reactions in the full pathway
−
* [[PWY-5084]], 2-oxoglutarate decarboxylation to succinyl-CoA:
+
* [[PWY-5994]], palmitate biosynthesis (type I fatty acid synthase):
−
** '''3''' reactions found over '''3''' reactions in the full pathway
+
** '''31''' reactions found over '''31''' reactions in the full pathway
 +
* [[PWY-7388]], octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast):
 +
** '''7''' reactions found over '''11''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
−
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
 
 
== External links  ==
 
== External links  ==
−
* RHEA:
+
* METANETX-RXN : MNXR115599
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=12189 12189]
+
* LIGAND-RXN:
−
* UNIPROT:
+
** [http://www.genome.jp/dbget-bin/www_bget?R04428 R04428]
−
** [http://www.uniprot.org/uniprot/P23129 P23129]
 
−
** [http://www.uniprot.org/uniprot/Q02218 Q02218]
 
−
** [http://www.uniprot.org/uniprot/Q60597 Q60597]
 
−
** [http://www.uniprot.org/uniprot/Q9JRJ8 Q9JRJ8]
 
−
** [http://www.uniprot.org/uniprot/P20967 P20967]
 
−
** [http://www.uniprot.org/uniprot/P0AFG3 P0AFG3]
 
−
** [http://www.uniprot.org/uniprot/P20707 P20707]
 
−
** [http://www.uniprot.org/uniprot/P51056 P51056]
 
−
** [http://www.uniprot.org/uniprot/Q56600 Q56600]
 
−
** [http://www.uniprot.org/uniprot/O49541 O49541]
 
−
** [http://www.uniprot.org/uniprot/Q59106 Q59106]
 
−
** [http://www.uniprot.org/uniprot/Q9M2T8 Q9M2T8]
 
−
** [http://www.uniprot.org/uniprot/Q9ZRQ2 Q9ZRQ2]
 
 
{{#set: direction=left-to-right}}
 
{{#set: direction=left-to-right}}
−
{{#set: common-name=2-oxoglutarate decarboxylase}}
+
{{#set: common-name=fatty acid synthase|(3r)-3-hydroxybutanoyl-[acyl-carrier-protein] hydratase|(3r)-3-hydroxybutanoyl-[acyl-carrier protein] dehydratase}}
−
{{#set: ec-number=ec-1.2.4.2}}
+
{{#set: ec-number=ec-4.2.1.59|ec-2.3.1.85|ec-2.3.1.86}}
−
{{#set: synonymous=2-oxoglutarate decarboxylation|oxoglutarate decarboxylase}}
+
{{#set: synonymous=3-hydroxybutyryl acyl carrier protein dehydratase|&beta;-hydroxybutyryl acyl carrier protein (acp) dehydrase|crotonoyl-[acyl-carrier-protein] hydratase|crotonyl acyl carrier protein hydratase|enoyl acyl carrier protein hydrase|&beta;-hydroxybutyryl acyl carrier  protein dehydrase|(3r)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase (but-2-enoyl-[acyl-carrier protein]-forming)|(3r)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase|&beta;-hydroxybutyryl acyl carrier protein dehydrase}}
−
{{#set: nb gene associated=3}}
+
{{#set: nb gene associated=16}}
−
{{#set: nb pathway associated=2}}
+
{{#set: nb pathway associated=3}}
−
{{#set: reconstruction category=annotation|orthology}}
+
{{#set: reconstruction category=annotation}}
−
{{#set: reconstruction tool=pathwaytools|pantograph}}
+
{{#set: reconstruction tool=pathwaytools}}
 
{{#set: reconstruction comment=n.a}}
 
{{#set: reconstruction comment=n.a}}
−
{{#set: reconstruction source=saccharina_japonica_genome|output_pantograph_ectocarpus_siliculosus}}
+
{{#set: reconstruction source=saccharina_japonica_genome}}

Latest revision as of 11:20, 18 March 2021

Reaction 4.2.1.58-RXN

  • direction:
    • left-to-right
  • common-name:
    • (3r)-3-hydroxybutanoyl-[acyl-carrier-protein] hydratase
    • fatty acid synthase
    • (3r)-3-hydroxybutanoyl-[acyl-carrier protein] dehydratase
  • ec-number:
  • synonymous:
    • β-hydroxybutyryl acyl carrier protein (acp) dehydrase
    • 3-hydroxybutyryl acyl carrier protein dehydratase
    • crotonyl acyl carrier protein hydratase
    • enoyl acyl carrier protein hydrase
    • (3r)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase (but-2-enoyl-[acyl-carrier protein]-forming)
    • β-hydroxybutyryl acyl carrier protein dehydrase
    • (3r)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase
    • crotonoyl-[acyl-carrier-protein] hydratase
    • β-hydroxybutyryl acyl carrier protein dehydrase

Reaction formula

Gene(s) associated with this reaction

Pathway(s)

  • PWY-5971, palmitate biosynthesis (type II fatty acid synthase):
    • 31 reactions found over 31 reactions in the full pathway
  • PWY-5994, palmitate biosynthesis (type I fatty acid synthase):
    • 31 reactions found over 31 reactions in the full pathway
  • PWY-7388, octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast):
    • 7 reactions found over 11 reactions in the full pathway

Reconstruction information

External links

  • METANETX-RXN : MNXR115599
  • LIGAND-RXN:
  • Property "Common-name" (as page type) with input value "(3r)-3-hydroxybutanoyl-[acyl-carrier-protein] hydratase" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.
  • Property "Common-name" (as page type) with input value "(3r)-3-hydroxybutanoyl-[acyl-carrier protein] dehydratase" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.
  • Property "Synonymous" (as page type) with input value "crotonoyl-[acyl-carrier-protein] hydratase" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.
  • Property "Synonymous" (as page type) with input value "(3r)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase (but-2-enoyl-[acyl-carrier protein]-forming)" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.
  • Property "Synonymous" (as page type) with input value "(3r)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.




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