Difference between revisions of "ARACHIDONATE-5-LIPOXYGENASE-RXN"

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(Created page with "Category:reaction == Reaction FUMHYDR-RXN == * direction: ** reversible * common-name: ** fumarase c * ec-number: ** [http://enzyme.expasy.org/EC/4.2.1.2 ec-4.2.1.2] * syn...")
(Created page with "Category:reaction == Reaction ARACHIDONATE-5-LIPOXYGENASE-RXN == * direction: ** left-to-right * common-name: ** arachidonate 5-lipoxygenase * synonymous: ** δ5-lipo...")
 
(4 intermediate revisions by one other user not shown)
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[[Category:reaction]]
 
[[Category:reaction]]
−
== Reaction FUMHYDR-RXN ==
+
== Reaction ARACHIDONATE-5-LIPOXYGENASE-RXN ==
 
* direction:
 
* direction:
−
** reversible
+
** left-to-right
 
* common-name:
 
* common-name:
−
** fumarase c
+
** arachidonate 5-lipoxygenase
−
* ec-number:
 
−
** [http://enzyme.expasy.org/EC/4.2.1.2 ec-4.2.1.2]
 
 
* synonymous:
 
* synonymous:
−
** malate dehydration
+
** δ5-lipoxygenase
−
** fumarate hydration
+
** c-5-lipoxygenase
 +
** arachidonic acid 5-lipoxygenase
 +
** leukotriene-a4 synthase
 +
** lta synthase
 +
** arachidonic 5-lipoxygenase
 +
** 5δ-lipoxygenase
 +
** leukotriene a4 synthase
 
== Reaction formula ==
 
== Reaction formula ==
−
* 1 [[MAL]][c] '''<=>''' 1 [[FUM]][c] '''+''' 1 [[WATER]][c]
+
* 1 [[ARACHIDONIC_ACID]][c] '''+''' 1 [[OXYGEN-MOLECULE]][c] '''=>''' 1 [[6E8Z11Z14Z-5S-5-HYDROPEROXYCOSA-6]][c]
 
== Gene(s) associated with this reaction  ==
 
== Gene(s) associated with this reaction  ==
−
* Gene: [[SJ05770]]
+
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
 +
* Gene: [[SJ12567]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 +
* Gene: [[SJ21862]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
* Gene: [[SJ08291]]
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
−
** Category: [[orthology]]
+
* Gene: [[SJ16634]]
−
*** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
−
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
−
* Gene: [[SJ06896]]
 
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
−
** Category: [[orthology]]
+
* Gene: [[SJ16633]]
−
*** Source: [[output_pantograph_nannochloropsis_salina]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
+
** Category: [[annotation]]
−
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
+
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 +
* Gene: [[SJ05859]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 +
* Gene: [[SJ16632]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 +
* Gene: [[SJ03316]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 +
* Gene: [[SJ08276]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 +
* Gene: [[SJ21859]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 +
* Gene: [[SJ05858]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 +
</div>
 
== Pathway(s)  ==
 
== Pathway(s)  ==
−
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
+
* [[PWY66-375]], leukotriene biosynthesis:
−
* [[PWY-5690]], TCA cycle II (plants and fungi):
+
** '''5''' reactions found over '''6''' reactions in the full pathway
−
** '''8''' reactions found over '''9''' reactions in the full pathway
 
−
* [[P108-PWY]], pyruvate fermentation to propanoate I:
 
−
** '''2''' reactions found over '''7''' reactions in the full pathway
 
−
* [[P105-PWY]], TCA cycle IV (2-oxoglutarate decarboxylase):
 
−
** '''10''' reactions found over '''11''' reactions in the full pathway
 
−
* [[TCA]], TCA cycle I (prokaryotic):
 
−
** '''9''' reactions found over '''10''' reactions in the full pathway
 
−
* [[REDCITCYC]], TCA cycle VI (Helicobacter):
 
−
** '''5''' reactions found over '''9''' reactions in the full pathway
 
−
* [[P42-PWY]], incomplete reductive TCA cycle:
 
−
** '''5''' reactions found over '''7''' reactions in the full pathway
 
−
* [[PWY66-398]], TCA cycle III (animals):
 
−
** '''10''' reactions found over '''10''' reactions in the full pathway
 
−
* [[PWY-7254]], TCA cycle VII (acetate-producers):
 
−
** '''7''' reactions found over '''9''' reactions in the full pathway
 
−
* [[PWY-6969]], TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase):
 
−
** '''10''' reactions found over '''12''' reactions in the full pathway
 
−
* [[PWY-5913]], partial TCA cycle (obligate autotrophs):
 
−
** '''10''' reactions found over '''11''' reactions in the full pathway
 
−
* [[PWY-561]], superpathway of glyoxylate cycle and fatty acid degradation:
 
−
** '''6''' reactions found over '''4''' reactions in the full pathway
 
−
* [[FERMENTATION-PWY]], mixed acid fermentation:
 
−
** '''11''' reactions found over '''16''' reactions in the full pathway
 
−
* [[P23-PWY]], reductive TCA cycle I:
 
−
** '''9''' reactions found over '''12''' reactions in the full pathway
 
−
* [[PWY-7384]], anaerobic energy metabolism (invertebrates, mitochondrial):
 
−
** '''6''' reactions found over '''10''' reactions in the full pathway
 
−
* [[PWY-6728]], methylaspartate cycle:
 
−
** '''11''' reactions found over '''19''' reactions in the full pathway
 
−
* [[PWY-5392]], reductive TCA cycle II:
 
−
** '''6''' reactions found over '''12''' reactions in the full pathway
 
−
</div>
 
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
−
* category: [[orthology]]; source: [[output_pantograph_arabidopsis_thaliana]]; tool: [[pantograph]]; comment: n.a
 
−
* category: [[orthology]]; source: [[output_pantograph_nannochloropsis_salina]]; tool: [[pantograph]]; comment: n.a
 
−
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
 
 
== External links  ==
 
== External links  ==
−
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
+
* METANETX-RXN : MNXR107077
 
* RHEA:
 
* RHEA:
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=12463 12463]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=17486 17486]
−
* PIR:
+
* LIGAND-RXN:
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A47692 A47692]
+
** [http://www.genome.jp/dbget-bin/www_bget?R01595 R01595]
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A49760 A49760]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A64377 A64377]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A81281 A81281]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A81807 A81807]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=B44511 B44511]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=B81862 B81862]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=E64461 E64461]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=E64685 E64685]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=H70896 H70896]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=H71462 H71462]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=JC4293 JC4293]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=JC4982 JC4982]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=PA0062 PA0062]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S40448 S40448]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S76348 S76348]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T00433 T00433]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T07374 T07374]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T41265 T41265]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T43727 T43727]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T45269 T45269]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=UFBSC8 UFBSC8]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=UFBYM UFBYM]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=UFEC UFEC]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=UFECAQ UFECAQ]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=UFHUM UFHUM]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=UFPG UFPG]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=UFRT UFRT]
 
 
* UNIPROT:
 
* UNIPROT:
−
** [http://www.uniprot.org/uniprot/Q04718 Q04718]
+
** [http://www.uniprot.org/uniprot/P12527 P12527]
−
** [http://www.uniprot.org/uniprot/Q58034 Q58034]
+
** [http://www.uniprot.org/uniprot/P09917 P09917]
−
** [http://www.uniprot.org/uniprot/O69294 O69294]
+
** [http://www.uniprot.org/uniprot/Q7M0C1 Q7M0C1]
−
** [http://www.uniprot.org/uniprot/Q9JTE3 Q9JTE3]
+
{{#set: direction=left-to-right}}
−
** [http://www.uniprot.org/uniprot/P14407 P14407]
+
{{#set: common-name=arachidonate 5-lipoxygenase}}
−
** [http://www.uniprot.org/uniprot/Q9JTR0 Q9JTR0]
+
{{#set: synonymous=5&delta;-lipoxygenase|leukotriene a4 synthase|arachidonic acid 5-lipoxygenase|lta synthase|leukotriene-a4 synthase|arachidonic 5-lipoxygenase|&delta;5-lipoxygenase|c-5-lipoxygenase}}
−
** [http://www.uniprot.org/uniprot/Q58690 Q58690]
+
{{#set: nb gene associated=11}}
−
** [http://www.uniprot.org/uniprot/O25883 O25883]
+
{{#set: nb pathway associated=1}}
−
** [http://www.uniprot.org/uniprot/O53446 O53446]
+
{{#set: reconstruction category=annotation}}
−
** [http://www.uniprot.org/uniprot/O84863 O84863]
+
{{#set: reconstruction tool=pathwaytools}}
−
** [http://www.uniprot.org/uniprot/Q51404 Q51404]
 
−
** [http://www.uniprot.org/uniprot/Q7M4Z3 Q7M4Z3]
 
−
** [http://www.uniprot.org/uniprot/P39461 P39461]
 
−
** [http://www.uniprot.org/uniprot/Q55674 Q55674]
 
−
** [http://www.uniprot.org/uniprot/P93033 P93033]
 
−
** [http://www.uniprot.org/uniprot/Q43180 Q43180]
 
−
** [http://www.uniprot.org/uniprot/O94552 O94552]
 
−
** [http://www.uniprot.org/uniprot/O66271 O66271]
 
−
** [http://www.uniprot.org/uniprot/Q60022 Q60022]
 
−
** [http://www.uniprot.org/uniprot/P07343 P07343]
 
−
** [http://www.uniprot.org/uniprot/P08417 P08417]
 
−
** [http://www.uniprot.org/uniprot/P05042 P05042]
 
−
** [http://www.uniprot.org/uniprot/P0AC33 P0AC33]
 
−
** [http://www.uniprot.org/uniprot/P10173 P10173]
 
−
** [http://www.uniprot.org/uniprot/P14408 P14408]
 
−
* LIGAND-RXN:
 
−
** [http://www.genome.jp/dbget-bin/www_bget?R01082 R01082]
 
−
</div>
 
−
{{#set: direction=reversible}}
 
−
{{#set: common-name=fumarase c}}
 
−
{{#set: ec-number=ec-4.2.1.2}}
 
−
{{#set: synonymous=fumarate hydration|malate dehydration}}
 
−
{{#set: nb gene associated=2}}
 
−
{{#set: nb pathway associated=16}}
 
−
{{#set: reconstruction category=annotation|orthology}}
 
−
{{#set: reconstruction tool=pathwaytools|pantograph}}
 
 
{{#set: reconstruction comment=n.a}}
 
{{#set: reconstruction comment=n.a}}
−
{{#set: reconstruction source=output_pantograph_nannochloropsis_salina|output_pantograph_arabidopsis_thaliana|saccharina_japonica_genome|output_pantograph_ectocarpus_siliculosus}}
+
{{#set: reconstruction source=saccharina_japonica_genome}}

Latest revision as of 11:19, 18 March 2021

Reaction ARACHIDONATE-5-LIPOXYGENASE-RXN

  • direction:
    • left-to-right
  • common-name:
    • arachidonate 5-lipoxygenase
  • synonymous:
    • δ5-lipoxygenase
    • c-5-lipoxygenase
    • arachidonic acid 5-lipoxygenase
    • leukotriene-a4 synthase
    • lta synthase
    • arachidonic 5-lipoxygenase
    • 5δ-lipoxygenase
    • leukotriene a4 synthase

Reaction formula

Gene(s) associated with this reaction

Pathway(s)

  • PWY66-375, leukotriene biosynthesis:
    • 5 reactions found over 6 reactions in the full pathway

Reconstruction information

External links





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