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| − | [[Category:reaction]] | + | [[Category:metabolite]] |
| − | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=FORMATETHFLIG-RXN FORMATETHFLIG-RXN] == | + | == Metabolite CPD-1302 == |
| − | * direction:
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| − | ** reversible
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| | * common-name: | | * common-name: |
| − | ** formate:tetrahydropteroylpolyglutamate ligase | + | ** 5-methyltetrahydropteroyl tri-l-glutamate |
| − | ** formate-tetrahydrofolate ligase
| + | * smiles: |
| − | * ec-number: | + | ** cn1([ch](cnc2(n=c(nc(=o)c1=2)n))cnc3(=cc=c(c(=o)nc(c([o-])=o)ccc(nc(c([o-])=o)ccc(nc(c([o-])=o)ccc(=o)[o-])=o)=o)c=c3)) |
| − | ** [http://enzyme.expasy.org/EC/6.3.4.3 ec-6.3.4.3] | + | * inchi-key: |
| − | == Reaction formula == | + | ** hvrnkdvlfavcjf-vjantymqsa-j |
| − | * 1 [[ATP]][c] '''+''' 1 [[FORMATE]][c] '''+''' 1 [[THF-GLU-N]][c] '''<=>''' 1 [[ADP]][c] '''+''' 1 [[FORMYL-THF-GLU-N]][c] '''+''' 1 [[Pi]][c]
| + | * molecular-weight: |
| − | == Gene(s) associated with this reaction == | + | ** 713.66 |
| − | * Gene: [[SJ12991]] | + | == Reaction(s) known to consume the compound == |
| − | ** Category: [[annotation]] | + | * [[HOMOCYSMET-RXN]] |
| − | *** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a | + | * [[RXN-12730]] |
| − | ** Category: [[orthology]]
| + | == Reaction(s) known to produce the compound == |
| − | *** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a | + | * [[HOMOCYSMET-RXN]] |
| − | * Gene: [[SJ07523]]
| + | == Reaction(s) of unknown directionality == |
| − | ** Category: [[annotation]]
| + | {{#set: common-name=5-methyltetrahydropteroyl tri-l-glutamate}} |
| − | *** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
| + | {{#set: inchi-key=inchikey=hvrnkdvlfavcjf-vjantymqsa-j}} |
| − | == Pathway(s) == | + | {{#set: molecular-weight=713.66}} |
| − | * [[PWY-2161]], folate polyglutamylation: [http://metacyc.org/META/NEW-IMAGE?object=PWY-2161 PWY-2161] | |
| − | ** '''5''' reactions found over '''5''' reactions in the full pathway
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| − | * [[PWY-2201]], folate transformations I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-2201 PWY-2201] | |
| − | ** '''9''' reactions found over '''12''' reactions in the full pathway
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| − | * [[PWY-1722]], formate assimilation into 5,10-methylenetetrahydrofolate: [http://metacyc.org/META/NEW-IMAGE?object=PWY-1722 PWY-1722]
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| − | ** '''3''' reactions found over '''3''' reactions in the full pathway
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| − | * [[CODH-PWY]], reductive acetyl coenzyme A pathway I (homoacetogenic bacteria): [http://metacyc.org/META/NEW-IMAGE?object=CODH-PWY CODH-PWY]
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| − | ** '''4''' reactions found over '''9''' reactions in the full pathway
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| − | * [[PWY-3841]], folate transformations II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-3841 PWY-3841]
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| − | ** '''9''' reactions found over '''11''' reactions in the full pathway
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| − | == Reconstruction information ==
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| − | * category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a | |
| − | * category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
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| − | == External links == | |
| − | * RHEA:
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| − | ** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=20224 20224]
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| − | * LIGAND-RXN:
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| − | ** [http://www.genome.jp/dbget-bin/www_bget?R00943 R00943]
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| − | * UNIPROT:
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| − | ** [http://www.uniprot.org/uniprot/P09440 P09440]
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| − | ** [http://www.uniprot.org/uniprot/P13419 P13419]
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| − | ** [http://www.uniprot.org/uniprot/P07245 P07245]
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| − | ** [http://www.uniprot.org/uniprot/P11586 P11586]
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| − | ** [http://www.uniprot.org/uniprot/P21164 P21164]
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| − | ** [http://www.uniprot.org/uniprot/P28723 P28723]
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| − | ** [http://www.uniprot.org/uniprot/Q9JVY8 Q9JVY8]
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| − | ** [http://www.uniprot.org/uniprot/Q9CH07 Q9CH07]
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| − | ** [http://www.uniprot.org/uniprot/Q07064 Q07064]
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| − | ** [http://www.uniprot.org/uniprot/Q27772 Q27772]
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| − | {{#set: direction=reversible}}
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| − | {{#set: common-name=formate:tetrahydropteroylpolyglutamate ligase|formate-tetrahydrofolate ligase}} | |
| − | {{#set: ec-number=ec-6.3.4.3}}
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| − | {{#set: nb gene associated=2}} | |
| − | {{#set: nb pathway associated=5}}
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| − | {{#set: reconstruction category=annotation|orthology}} | |
| − | {{#set: reconstruction tool=pantograph|pathwaytools}}
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| − | {{#set: reconstruction comment=n.a}}
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| − | {{#set: reconstruction source=output_pantograph_ectocarpus_siliculosus|saccharina_japonica_genome}}
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