Difference between revisions of "CPD-15424"

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(Created page with "Category:reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN66-305 RXN66-305] == * direction: ** left-to-right * common-name: ** 14-oxolanosterol deformylas...")
 
(Created page with "Category:reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN] == * direction: ** r...")
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[[Category:reaction]]
 
[[Category:reaction]]
−
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN66-305 RXN66-305] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN] ==
 
* direction:
 
* direction:
−
** left-to-right
+
** reversible
 
* common-name:
 
* common-name:
−
** 14-oxolanosterol deformylase
+
** hydroxymethyl glutaryl-coa synthase
−
** 4,4-dimethyl-14α-formyl-5α-cholesta-8,24-dien-3β-ol,nadph:oxygen oxidoreductase (14-methyl cleaving)
+
* ec-number:
 +
** [http://enzyme.expasy.org/EC/2.3.3.10 ec-2.3.3.10]
 
== Reaction formula ==
 
== Reaction formula ==
−
* 1 [[CPD-4573]][c] '''+''' 1 [[NADPH]][c] '''+''' 1 [[OXYGEN-MOLECULE]][c] '''=>''' 1 [[44-DIMETHYL-CHOLESTA-814-24-TRIENOL]][c] '''+''' 1 [[FORMATE]][c] '''+''' 1 [[NADP]][c] '''+''' 1 [[WATER]][c]
+
* 1 [[ACETOACETYL-COA]][c] '''+''' 1 [[ACETYL-COA]][c] '''+''' 1 [[WATER]][c] '''<=>''' 1 [[3-HYDROXY-3-METHYL-GLUTARYL-COA]][c] '''+''' 1 [[CO-A]][c] '''+''' 1 [[PROTON]][c]
 
== Gene(s) associated with this reaction  ==
 
== Gene(s) associated with this reaction  ==
−
* Gene: [[SJ05072]]
+
* Gene: [[SJ06617]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 +
** Category: [[orthology]]
 +
*** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 +
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 +
* Gene: [[SJ11593]]
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
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*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
== Pathway(s)  ==
 
== Pathway(s)  ==
−
* [[PWY66-341]], cholesterol biosynthesis I: [http://metacyc.org/META/NEW-IMAGE?object=PWY66-341 PWY66-341]
+
* [[PWY-7391]], isoprene biosynthesis II (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7391 PWY-7391]
−
** '''14''' reactions found over '''18''' reactions in the full pathway
+
** '''7''' reactions found over '''8''' reactions in the full pathway
−
* [[PWY66-4]], cholesterol biosynthesis III (via desmosterol): [http://metacyc.org/META/NEW-IMAGE?object=PWY66-4 PWY66-4]
+
* [[PWY-7524]], mevalonate pathway III (archaea): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7524 PWY-7524]
−
** '''14''' reactions found over '''4''' reactions in the full pathway
+
** '''5''' reactions found over '''8''' reactions in the full pathway
 +
* [[PWY-922]], mevalonate pathway I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-922 PWY-922]
 +
** '''7''' reactions found over '''7''' reactions in the full pathway
 +
* [[PWY-6174]], mevalonate pathway II (archaea): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6174 PWY-6174]
 +
** '''6''' reactions found over '''7''' reactions in the full pathway
 +
* [[PWY66-367]], ketogenesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY66-367 PWY66-367]
 +
** '''4''' reactions found over '''5''' reactions in the full pathway
 +
* [[PWY-7571]], ferrichrome A biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7571 PWY-7571]
 +
** '''1''' reactions found over '''5''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 +
* category: [[orthology]]; source: [[output_pantograph_arabidopsis_thaliana]]; tool: [[pantograph]]; comment: n.a
 
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
 
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 
== External links  ==
 
== External links  ==
−
{{#set: direction=left-to-right}}
+
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
−
{{#set: common-name=4,4-dimethyl-14&alpha;-formyl-5&alpha;-cholesta-8,24-dien-3&beta;-ol,nadph:oxygen oxidoreductase (14-methyl cleaving)|14-oxolanosterol deformylase}}
+
* RHEA:
−
{{#set: nb gene associated=1}}
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=10191 10191]
−
{{#set: nb pathway associated=2}}
+
* LIGAND-RXN:
 +
** [http://www.genome.jp/dbget-bin/www_bget?R01978 R01978]
 +
* UNIPROT:
 +
** [http://www.uniprot.org/uniprot/P13704 P13704]
 +
** [http://www.uniprot.org/uniprot/P22791 P22791]
 +
** [http://www.uniprot.org/uniprot/P54870 P54870]
 +
** [http://www.uniprot.org/uniprot/P54869 P54869]
 +
** [http://www.uniprot.org/uniprot/O51626 O51626]
 +
** [http://www.uniprot.org/uniprot/Q9CFA9 Q9CFA9]
 +
** [http://www.uniprot.org/uniprot/P17425 P17425]
 +
** [http://www.uniprot.org/uniprot/Q7LZE7 Q7LZE7]
 +
** [http://www.uniprot.org/uniprot/Q01581 Q01581]
 +
** [http://www.uniprot.org/uniprot/P54961 P54961]
 +
** [http://www.uniprot.org/uniprot/P54839 P54839]
 +
** [http://www.uniprot.org/uniprot/P54874 P54874]
 +
** [http://www.uniprot.org/uniprot/P54868 P54868]
 +
** [http://www.uniprot.org/uniprot/P54873 P54873]
 +
** [http://www.uniprot.org/uniprot/P93773 P93773]
 +
</div>
 +
{{#set: direction=reversible}}
 +
{{#set: common-name=hydroxymethyl glutaryl-coa synthase}}
 +
{{#set: ec-number=ec-2.3.3.10}}
 +
{{#set: nb gene associated=2}}
 +
{{#set: nb pathway associated=6}}
 
{{#set: reconstruction category=orthology|annotation}}
 
{{#set: reconstruction category=orthology|annotation}}
−
{{#set: reconstruction tool=pathwaytools|pantograph}}
+
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
{{#set: reconstruction comment=n.a}}
 
{{#set: reconstruction comment=n.a}}
−
{{#set: reconstruction source=output_pantograph_ectocarpus_siliculosus|saccharina_japonica_genome}}
+
{{#set: reconstruction source=output_pantograph_arabidopsis_thaliana|output_pantograph_ectocarpus_siliculosus|saccharina_japonica_genome}}

Revision as of 14:25, 26 August 2019

Reaction HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN

  • direction:
    • reversible
  • common-name:
    • hydroxymethyl glutaryl-coa synthase
  • ec-number:

Reaction formula

Gene(s) associated with this reaction

Pathway(s)

  • PWY-7391, isoprene biosynthesis II (engineered): PWY-7391
    • 7 reactions found over 8 reactions in the full pathway
  • PWY-7524, mevalonate pathway III (archaea): PWY-7524
    • 5 reactions found over 8 reactions in the full pathway
  • PWY-922, mevalonate pathway I: PWY-922
    • 7 reactions found over 7 reactions in the full pathway
  • PWY-6174, mevalonate pathway II (archaea): PWY-6174
    • 6 reactions found over 7 reactions in the full pathway
  • PWY66-367, ketogenesis: PWY66-367
    • 4 reactions found over 5 reactions in the full pathway
  • PWY-7571, ferrichrome A biosynthesis: PWY-7571
    • 1 reactions found over 5 reactions in the full pathway

Reconstruction information

External links





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