Difference between revisions of "CYSTATHIONINE-BETA-SYNTHASE-RXN"

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(Created page with "Category:reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=ACETYL-COA-ACETYLTRANSFER-RXN ACETYL-COA-ACETYLTRANSFER-RXN] == * direction: ** reversible * common...")
(Created page with "Category:reaction == Reaction CYSTATHIONINE-BETA-SYNTHASE-RXN == * direction: ** reversible * common-name: ** cystathionine β-synthase * ec-number: ** [http://enzyme....")
 
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[[Category:reaction]]
 
[[Category:reaction]]
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=ACETYL-COA-ACETYLTRANSFER-RXN ACETYL-COA-ACETYLTRANSFER-RXN] ==
+
== Reaction CYSTATHIONINE-BETA-SYNTHASE-RXN ==
 
* direction:
 
* direction:
 
** reversible
 
** reversible
 
* common-name:
 
* common-name:
** acetyl-coa acetyltransferase
+
** cystathionine β-synthase
 
* ec-number:
 
* ec-number:
** [http://enzyme.expasy.org/EC/2.3.1.9 ec-2.3.1.9]
+
** [http://enzyme.expasy.org/EC/4.2.1.22 ec-4.2.1.22]
 
== Reaction formula ==
 
== Reaction formula ==
* 2 [[ACETYL-COA]][c] '''<=>''' 1 [[ACETOACETYL-COA]][c] '''+''' 1 [[CO-A]][c]
+
* 1 [[HOMO-CYS]][c] '''+''' 1 [[SER]][c] '''<=>''' 1 [[L-CYSTATHIONINE]][c] '''+''' 1 [[WATER]][c]
 
== Gene(s) associated with this reaction  ==
 
== Gene(s) associated with this reaction  ==
* Gene: [[SJ09371]]
+
* Gene: [[SJ15937]]
** Category: [[orthology]]
 
*** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
* Gene: [[SJ14898]]
 
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
** Category: [[orthology]]
 
** Category: [[orthology]]
*** Source: [[output_pantograph_nannochloropsis_salina]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
*** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
*** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
*** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
*** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
* Gene: [[SJ21818]]
+
* Gene: [[SJ20026]]
 
** Category: [[orthology]]
 
** Category: [[orthology]]
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
+
*** Source: [[output_pantograph_nannochloropsis_salina]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 +
* Gene: [[SJ15938]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
== Pathway(s)  ==
 
== Pathway(s)  ==
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
+
* [[HOMOCYSDEGR-PWY]], L-cysteine biosynthesis III (from L-homocysteine):
* [[PWY-6174]], mevalonate pathway II (archaea): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6174 PWY-6174]
+
** '''2''' reactions found over '''2''' reactions in the full pathway
** '''6''' reactions found over '''7''' reactions in the full pathway
+
* [[PWY-I9]], L-cysteine biosynthesis VI (from L-methionine):
* [[PWY-6883]], pyruvate fermentation to butanol II (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6883 PWY-6883]
 
** '''5''' reactions found over '''6''' reactions in the full pathway
 
* [[PWY-6876]], isopropanol biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6876 PWY-6876]
 
** '''2''' reactions found over '''5''' reactions in the full pathway
 
* [[ACETOACETATE-DEG-PWY]], acetoacetate degradation (to acetyl CoA): [http://metacyc.org/META/NEW-IMAGE?object=ACETOACETATE-DEG-PWY ACETOACETATE-DEG-PWY]
 
** '''1''' reactions found over '''2''' reactions in the full pathway
 
* [[PWY-5177]], glutaryl-CoA degradation: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5177 PWY-5177]
 
** '''5''' reactions found over '''5''' reactions in the full pathway
 
* [[PWY-6588]], pyruvate fermentation to acetone: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6588 PWY-6588]
 
** '''2''' reactions found over '''5''' reactions in the full pathway
 
* [[PWY-922]], mevalonate pathway I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-922 PWY-922]
 
** '''7''' reactions found over '''7''' reactions in the full pathway
 
* [[PWY-6583]], pyruvate fermentation to butanol I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6583 PWY-6583]
 
** '''6''' reactions found over '''8''' reactions in the full pathway
 
* [[PWY-5789]], 3-hydroxypropanoate/4-hydroxybutanate cycle: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5789 PWY-5789]
 
** '''8''' reactions found over '''18''' reactions in the full pathway
 
* [[PWY1-3]], polyhydroxybutanoate biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY1-3 PWY1-3]
 
** '''2''' reactions found over '''3''' reactions in the full pathway
 
* [[PWY-7216]], (R)- and (S)-3-hydroxybutanoate biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7216 PWY-7216]
 
** '''3''' reactions found over '''5''' reactions in the full pathway
 
* [[PWY-7401]], crotonate fermentation (to acetate and cyclohexane carboxylate): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7401 PWY-7401]
 
** '''6''' reactions found over '''15''' reactions in the full pathway
 
* [[PWY-7391]], isoprene biosynthesis II (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7391 PWY-7391]
 
** '''7''' reactions found over '''8''' reactions in the full pathway
 
* [[P162-PWY]], L-glutamate degradation V (via hydroxyglutarate): [http://metacyc.org/META/NEW-IMAGE?object=P162-PWY P162-PWY]
 
** '''7''' reactions found over '''11''' reactions in the full pathway
 
* [[PWY-5741]], ethylmalonyl-CoA pathway: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5741 PWY-5741]
 
** '''2''' reactions found over '''11''' reactions in the full pathway
 
* [[PWY-6863]], pyruvate fermentation to hexanol (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6863 PWY-6863]
 
** '''9''' reactions found over '''11''' reactions in the full pathway
 
* [[P163-PWY]], L-lysine fermentation to acetate and butanoate: [http://metacyc.org/META/NEW-IMAGE?object=P163-PWY P163-PWY]
 
** '''3''' reactions found over '''10''' reactions in the full pathway
 
* [[PWY-7779]], methyl tert-butyl ether degradation: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7779 PWY-7779]
 
** '''2''' reactions found over '''10''' reactions in the full pathway
 
* [[PWY-7778]], 2-methylpropene degradation: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7778 PWY-7778]
 
** '''3''' reactions found over '''8''' reactions in the full pathway
 
* [[PWY-7524]], mevalonate pathway III (archaea): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7524 PWY-7524]
 
** '''5''' reactions found over '''8''' reactions in the full pathway
 
* [[PWY66-368]], ketolysis: [http://metacyc.org/META/NEW-IMAGE?object=PWY66-368 PWY66-368]
 
** '''2''' reactions found over '''3''' reactions in the full pathway
 
* [[PWY66-367]], ketogenesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY66-367 PWY66-367]
 
 
** '''4''' reactions found over '''5''' reactions in the full pathway
 
** '''4''' reactions found over '''5''' reactions in the full pathway
* [[PWY-5676]], acetyl-CoA fermentation to butanoate II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5676 PWY-5676]
+
* [[PWY-801]], homocysteine and cysteine interconversion:
** '''4''' reactions found over '''5''' reactions in the full pathway
+
** '''3''' reactions found over '''4''' reactions in the full pathway
* [[CENTFERM-PWY]], pyruvate fermentation to butanoate: [http://metacyc.org/META/NEW-IMAGE?object=CENTFERM-PWY CENTFERM-PWY]
 
** '''5''' reactions found over '''7''' reactions in the full pathway
 
</div>
 
 
== Reconstruction information  ==
 
== Reconstruction information  ==
* category: [[orthology]]; source: [[output_pantograph_arabidopsis_thaliana]]; tool: [[pantograph]]; comment: n.a
+
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 +
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
 
* category: [[orthology]]; source: [[output_pantograph_nannochloropsis_salina]]; tool: [[pantograph]]; comment: n.a
 
* category: [[orthology]]; source: [[output_pantograph_nannochloropsis_salina]]; tool: [[pantograph]]; comment: n.a
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 
 
== External links  ==
 
== External links  ==
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
+
* METANETX-RXN : MNXR97019
 
* RHEA:
 
* RHEA:
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=21039 21039]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=10115 10115]
 
* LIGAND-RXN:
 
* LIGAND-RXN:
** [http://www.genome.jp/dbget-bin/www_bget?R00238 R00238]
+
** [http://www.genome.jp/dbget-bin/www_bget?R01290 R01290]
 
* UNIPROT:
 
* UNIPROT:
** [http://www.uniprot.org/uniprot/Q8CAY6 Q8CAY6]
+
** [http://www.uniprot.org/uniprot/P32232 P32232]
** [http://www.uniprot.org/uniprot/P41338 P41338]
+
** [http://www.uniprot.org/uniprot/P32582 P32582]
** [http://www.uniprot.org/uniprot/P45362 P45362]
+
** [http://www.uniprot.org/uniprot/P35520 P35520]
** [http://www.uniprot.org/uniprot/Q9BWD1 Q9BWD1]
+
** [http://www.uniprot.org/uniprot/Q9YCN5 Q9YCN5]
** [http://www.uniprot.org/uniprot/P45359 P45359]
+
** [http://www.uniprot.org/uniprot/Q12633 Q12633]
** [http://www.uniprot.org/uniprot/P24752 P24752]
+
** [http://www.uniprot.org/uniprot/P72662 P72662]
** [http://www.uniprot.org/uniprot/Q12598 Q12598]
+
** [http://www.uniprot.org/uniprot/O59701 O59701]
** [http://www.uniprot.org/uniprot/P45369 P45369]
 
** [http://www.uniprot.org/uniprot/P46707 P46707]
 
** [http://www.uniprot.org/uniprot/P73825 P73825]
 
** [http://www.uniprot.org/uniprot/Q43637 Q43637]
 
** [http://www.uniprot.org/uniprot/Q9UQW6 Q9UQW6]
 
** [http://www.uniprot.org/uniprot/Q9Z3Y4 Q9Z3Y4]
 
** [http://www.uniprot.org/uniprot/P77852 P77852]
 
** [http://www.uniprot.org/uniprot/Q9XD81 Q9XD81]
 
** [http://www.uniprot.org/uniprot/Q9ZGI9 Q9ZGI9]
 
** [http://www.uniprot.org/uniprot/Q9L8E0 Q9L8E0]
 
** [http://www.uniprot.org/uniprot/P14611 P14611]
 
** [http://www.uniprot.org/uniprot/P07097 P07097]
 
** [http://www.uniprot.org/uniprot/P17764 P17764]
 
</div>
 
 
{{#set: direction=reversible}}
 
{{#set: direction=reversible}}
{{#set: common-name=acetyl-coa acetyltransferase}}
+
{{#set: common-name=cystathionine &beta;-synthase}}
{{#set: ec-number=ec-2.3.1.9}}
+
{{#set: ec-number=ec-4.2.1.22}}
 
{{#set: nb gene associated=3}}
 
{{#set: nb gene associated=3}}
{{#set: nb pathway associated=24}}
+
{{#set: nb pathway associated=3}}
{{#set: reconstruction category=annotation|orthology}}
+
{{#set: reconstruction category=orthology|annotation}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
{{#set: reconstruction comment=n.a}}
 
{{#set: reconstruction comment=n.a}}
{{#set: reconstruction source=output_pantograph_ectocarpus_siliculosus|output_pantograph_arabidopsis_thaliana|saccharina_japonica_genome|output_pantograph_nannochloropsis_salina}}
+
{{#set: reconstruction source=output_pantograph_nannochloropsis_salina|output_pantograph_ectocarpus_siliculosus|saccharina_japonica_genome}}

Latest revision as of 11:21, 18 March 2021

Reaction CYSTATHIONINE-BETA-SYNTHASE-RXN

  • direction:
    • reversible
  • common-name:
    • cystathionine β-synthase
  • ec-number:

Reaction formula

Gene(s) associated with this reaction

Pathway(s)

  • HOMOCYSDEGR-PWY, L-cysteine biosynthesis III (from L-homocysteine):
    • 2 reactions found over 2 reactions in the full pathway
  • PWY-I9, L-cysteine biosynthesis VI (from L-methionine):
    • 4 reactions found over 5 reactions in the full pathway
  • PWY-801, homocysteine and cysteine interconversion:
    • 3 reactions found over 4 reactions in the full pathway

Reconstruction information

External links