EIF5A-HYPUSINE

Reaction 5-FORMYL-THF-CYCLO-LIGASE-RXN

• direction:
  • left-to-right
• common-name:
  • 5-formyltetrahydrofolate cyclo-ligase
• ec-number:
  • ec-6.3.3.2

Reaction formula

• 1 ATP[c] + 1 N5-Formyl-THF-Glu-N[c] => 1 5-10-METHENYL-THF-GLU-N[c] + 1 ADP[c] + 1 Pi[c]

Gene(s) associated with this reaction

• Gene: SJ02064
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: ec-number, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: SJ19600
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a

Pathway(s)

• PWY-3841, folate transformations II: PWY-3841
  • 9 reactions found over 11 reactions in the full pathway
• PWY-2201, folate transformations I: PWY-2201
  • 9 reactions found over 12 reactions in the full pathway
• 1CMET2-PWY, N10-formyl-tetrahydrofolate biosynthesis: 1CMET2-PWY
  • 8 reactions found over 9 reactions in the full pathway

Reconstruction information

• category: orthology; source: output_pantograph_ectocarpus_siliculosus; tool: pantograph; comment: n.a
• category: annotation; source: saccharina_japonica_genome; tool: pathwaytools; comment: n.a

External links

• RHEA:
  • 10489
• LIGAND-RXN:
  • R02301
• UNIPROT:
  • P80405
  • P49914