Difference between revisions of "FATTY-ACID-SYNTHASE-RXN"

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(Created page with "Category:reaction == Reaction RXN-11662 == * direction: ** reversible * common-name: ** (s)-3-hydroxybutanoyl-coa dehydrogeanse ** 3-hydroxyacyl-coa dehydrogenase * ec-num...")
(Created page with "Category:reaction == Reaction FATTY-ACID-SYNTHASE-RXN == * direction: ** left-to-right * common-name: ** fatty acid synthase * ec-number: ** [http://enzyme.expasy.org/EC/2...")
 
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[[Category:reaction]]
 
[[Category:reaction]]
−
== Reaction RXN-11662 ==
+
== Reaction FATTY-ACID-SYNTHASE-RXN ==
 
* direction:
 
* direction:
−
** reversible
+
** left-to-right
 
* common-name:
 
* common-name:
−
** (s)-3-hydroxybutanoyl-coa dehydrogeanse
+
** fatty acid synthase
−
** 3-hydroxyacyl-coa dehydrogenase
 
 
* ec-number:
 
* ec-number:
−
** [http://enzyme.expasy.org/EC/1.1.1.35 ec-1.1.1.35]
+
** [http://enzyme.expasy.org/EC/2.3.1.85 ec-2.3.1.85]
 
== Reaction formula ==
 
== Reaction formula ==
−
* 1 [[NAD]][c] '''+''' 1 [[S-3-HYDROXYBUTANOYL-COA]][c] '''<=>''' 1 [[ACETOACETYL-COA]][c] '''+''' 1 [[NADH]][c] '''+''' 1 [[PROTON]][c]
+
* 1 [[ACETYL-COA]][c] '''+''' n [[MALONYL-COA]][c] '''+''' 2n [[NADPH]][c] '''+''' 2n [[PROTON]][c] '''=>''' n [[CARBON-DIOXIDE]][c] '''+''' (n+1) [[CO-A]][c] '''+''' 1 [[Long-Chain-Fatty-Acids]][c] '''+''' 2n [[NADP]][c]
 
== Gene(s) associated with this reaction  ==
 
== Gene(s) associated with this reaction  ==
 
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
 
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
−
* Gene: [[SJ21390]]
+
* Gene: [[SJ06616]]
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
−
** Category: [[orthology]]
+
* Gene: [[SJ04443]]
−
*** Source: [[output_pantograph_nannochloropsis_salina]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
−
*** Source: [[output_pantograph_nannochloropsis_salina]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
−
* Gene: [[SJ17348]]
 
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
−
* Gene: [[SJ16470]]
+
* Gene: [[SJ15983]]
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
−
* Gene: [[SJ16180]]
+
* Gene: [[SJ11672]]
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
−
* Gene: [[SJ03584]]
+
* Gene: [[SJ10624]]
 
** Category: [[annotation]]
 
** Category: [[annotation]]
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
+
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
−
** Category: [[orthology]]
+
* Gene: [[SJ18059]]
−
*** Source: [[output_pantograph_nannochloropsis_salina]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
+
** Category: [[annotation]]
−
* Gene: [[SJ06127]]
+
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
* Gene: [[SJ00320]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
* Gene: [[SJ13014]]
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
−
* Gene: [[SJ07211]]
+
* Gene: [[SJ06944]]
 
** Category: [[annotation]]
 
** Category: [[annotation]]
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
+
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
−
** Category: [[orthology]]
+
* Gene: [[SJ03883]]
−
*** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
−
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
−
* Gene: [[SJ01444]]
 
 
** Category: [[annotation]]
 
** Category: [[annotation]]
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
+
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
* Gene: [[SJ17743]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
* Gene: [[SJ19629]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
* Gene: [[SJ06617]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
* Gene: [[SJ04769]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
* Gene: [[SJ00613]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
</div>
 
</div>
 
== Pathway(s)  ==
 
== Pathway(s)  ==
−
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
 
−
* [[PWY-5177]], glutaryl-CoA degradation:
 
−
** '''5''' reactions found over '''5''' reactions in the full pathway
 
−
* [[PWY-7778]], 2-methylpropene degradation:
 
−
** '''3''' reactions found over '''8''' reactions in the full pathway
 
−
* [[PWY-6863]], pyruvate fermentation to hexanol (engineered):
 
−
** '''9''' reactions found over '''11''' reactions in the full pathway
 
−
* [[CENTFERM-PWY]], pyruvate fermentation to butanoate:
 
−
** '''5''' reactions found over '''7''' reactions in the full pathway
 
−
* [[PWY-6583]], pyruvate fermentation to butanol I:
 
−
** '''6''' reactions found over '''8''' reactions in the full pathway
 
−
* [[PWY-6883]], pyruvate fermentation to butanol II (engineered):
 
−
** '''5''' reactions found over '''6''' reactions in the full pathway
 
−
* [[PWY-5789]], 3-hydroxypropanoate/4-hydroxybutanate cycle:
 
−
** '''8''' reactions found over '''18''' reactions in the full pathway
 
−
* [[P162-PWY]], L-glutamate degradation V (via hydroxyglutarate):
 
−
** '''7''' reactions found over '''11''' reactions in the full pathway
 
−
* [[PWY-7216]], (R)- and (S)-3-hydroxybutanoate biosynthesis (engineered):
 
−
** '''3''' reactions found over '''5''' reactions in the full pathway
 
−
* [[PWY-7401]], crotonate fermentation (to acetate and cyclohexane carboxylate):
 
−
** '''6''' reactions found over '''15''' reactions in the full pathway
 
−
* [[PWY-7779]], methyl tert-butyl ether degradation:
 
−
** '''2''' reactions found over '''10''' reactions in the full pathway
 
−
</div>
 
 
== Reconstruction information  ==
 
== Reconstruction information  ==
−
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
 
−
* category: [[orthology]]; source: [[output_pantograph_nannochloropsis_salina]]; tool: [[pantograph]]; comment: n.a
 
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
−
* category: [[orthology]]; source: [[output_pantograph_arabidopsis_thaliana]]; tool: [[pantograph]]; comment: n.a
 
 
== External links  ==
 
== External links  ==
−
* RHEA:
+
* METANETX-RXN : MNXR109383
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=30802 30802]
 
 
* LIGAND-RXN:
 
* LIGAND-RXN:
−
** [http://www.genome.jp/dbget-bin/www_bget?R01975 R01975]
+
** [http://www.genome.jp/dbget-bin/www_bget?R05188 R05188]
−
{{#set: direction=reversible}}
+
* UNIPROT:
−
{{#set: common-name=3-hydroxyacyl-coa dehydrogenase|(s)-3-hydroxybutanoyl-coa dehydrogeanse}}
+
** [http://www.uniprot.org/uniprot/P36189 P36189]
−
{{#set: ec-number=ec-1.1.1.35}}
+
** [http://www.uniprot.org/uniprot/P49327 P49327]
−
{{#set: nb gene associated=8}}
+
** [http://www.uniprot.org/uniprot/P95029 P95029]
−
{{#set: nb pathway associated=11}}
+
** [http://www.uniprot.org/uniprot/P43098 P43098]
−
{{#set: reconstruction category=annotation|orthology}}
+
** [http://www.uniprot.org/uniprot/Q48926 Q48926]
−
{{#set: reconstruction tool=pathwaytools|pantograph}}
+
** [http://www.uniprot.org/uniprot/P15368 P15368]
 +
** [http://www.uniprot.org/uniprot/P08757 P08757]
 +
** [http://www.uniprot.org/uniprot/P07855 P07855]
 +
** [http://www.uniprot.org/uniprot/Q04846 Q04846]
 +
** [http://www.uniprot.org/uniprot/Q59497 Q59497]
 +
** [http://www.uniprot.org/uniprot/P19097 P19097]
 +
** [http://www.uniprot.org/uniprot/P78866 P78866]
 +
** [http://www.uniprot.org/uniprot/Q10289 Q10289]
 +
** [http://www.uniprot.org/uniprot/P12276 P12276]
 +
** [http://www.uniprot.org/uniprot/P12785 P12785]
 +
{{#set: direction=left-to-right}}
 +
{{#set: common-name=fatty acid synthase}}
 +
{{#set: ec-number=ec-2.3.1.85}}
 +
{{#set: nb gene associated=15}}
 +
{{#set: nb pathway associated=0}}
 +
{{#set: reconstruction category=annotation}}
 +
{{#set: reconstruction tool=pathwaytools}}
 
{{#set: reconstruction comment=n.a}}
 
{{#set: reconstruction comment=n.a}}
−
{{#set: reconstruction source=output_pantograph_nannochloropsis_salina|output_pantograph_arabidopsis_thaliana|saccharina_japonica_genome|output_pantograph_ectocarpus_siliculosus}}
+
{{#set: reconstruction source=saccharina_japonica_genome}}

Latest revision as of 11:21, 18 March 2021

Reaction FATTY-ACID-SYNTHASE-RXN

  • direction:
    • left-to-right
  • common-name:
    • fatty acid synthase
  • ec-number:

Reaction formula

Gene(s) associated with this reaction

Pathway(s)

Reconstruction information

External links





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