Difference between revisions of "FORMATETHFLIG-RXN"

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(Created page with "Category:reaction == Reaction RXN-9654 == * direction: ** left-to-right * common-name: ** fatty acid synthase * ec-number: ** [http://enzyme.expasy.org/EC/2.3.1.86 ec-2.3....")
(Created page with "Category:reaction == Reaction FORMATETHFLIG-RXN == * direction: ** reversible * common-name: ** formate:tetrahydropteroylpolyglutamate ligase ** formate-tetrahydrofolate l...")
 
(3 intermediate revisions by 2 users not shown)
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[[Category:reaction]]
 
[[Category:reaction]]
−
== Reaction RXN-9654 ==
+
== Reaction FORMATETHFLIG-RXN ==
 
* direction:
 
* direction:
−
** left-to-right
+
** reversible
 
* common-name:
 
* common-name:
−
** fatty acid synthase
+
** formate:tetrahydropteroylpolyglutamate ligase
 +
** formate-tetrahydrofolate ligase
 
* ec-number:
 
* ec-number:
−
** [http://enzyme.expasy.org/EC/2.3.1.86 ec-2.3.1.86]
+
** [http://enzyme.expasy.org/EC/6.3.4.3 ec-6.3.4.3]
−
** [http://enzyme.expasy.org/EC/2.3.1.85 ec-2.3.1.85]
 
−
** [http://enzyme.expasy.org/EC/2.3.1.41 ec-2.3.1.41]
 
 
== Reaction formula ==
 
== Reaction formula ==
−
* 1 [[MALONYL-COA]][c] '''+''' 1 [[Myristoyl-ACPs]][c] '''+''' 1 [[PROTON]][c] '''=>''' 1 [[3-oxo-palmitoyl-ACPs]][c] '''+''' 1 [[CARBON-DIOXIDE]][c] '''+''' 1 [[CO-A]][c]
+
* 1 [[ATP]][c] '''+''' 1 [[FORMATE]][c] '''+''' 1 [[THF-GLU-N]][c] '''<=>''' 1 [[ADP]][c] '''+''' 1 [[FORMYL-THF-GLU-N]][c] '''+''' 1 [[Pi]][c]
 
== Gene(s) associated with this reaction  ==
 
== Gene(s) associated with this reaction  ==
−
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
+
* Gene: [[SJ12991]]
−
* Gene: [[SJ15984]]
 
−
** Category: [[orthology]]
 
−
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
−
* Gene: [[SJ11672]]
 
 
** Category: [[annotation]]
 
** Category: [[annotation]]
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
+
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
−
* Gene: [[SJ10624]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ18059]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ06617]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ15983]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
 
** Category: [[orthology]]
 
** Category: [[orthology]]
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
−
* Gene: [[SJ19629]]
+
* Gene: [[SJ07523]]
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ13014]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ03883]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ06616]]
 
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
−
* Gene: [[SJ04769]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ00320]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ00613]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ06944]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ04443]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
** Category: [[orthology]]
 
−
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
−
* Gene: [[SJ17743]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ00005]]
 
−
** Category: [[orthology]]
 
−
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
−
</div>
 
 
== Pathway(s)  ==
 
== Pathway(s)  ==
−
* [[PWY-5994]], palmitate biosynthesis (animals and fungi, cytoplasm):
+
* [[PWY-2161]], folate polyglutamylation:
−
** '''31''' reactions found over '''31''' reactions in the full pathway
+
** '''5''' reactions found over '''5''' reactions in the full pathway
 +
* [[PWY-2201]], folate transformations I:
 +
** '''9''' reactions found over '''10''' reactions in the full pathway
 +
* [[PWY-1722]], formate assimilation into 5,10-methylenetetrahydrofolate:
 +
** '''3''' reactions found over '''3''' reactions in the full pathway
 +
* [[CODH-PWY]], reductive acetyl coenzyme A pathway I (homoacetogenic bacteria):
 +
** '''4''' reactions found over '''10''' reactions in the full pathway
 +
* [[PWY-3841]], folate transformations II (plants):
 +
** '''9''' reactions found over '''11''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
 
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
 
== External links  ==
 
== External links  ==
−
{{#set: direction=left-to-right}}
+
* METANETX-RXN : MNXR115886
−
{{#set: common-name=fatty acid synthase}}
+
* RHEA:
−
{{#set: ec-number=ec-2.3.1.41|ec-2.3.1.86|ec-2.3.1.85}}
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=20224 20224]
−
{{#set: nb gene associated=17}}
+
* LIGAND-RXN:
−
{{#set: nb pathway associated=1}}
+
** [http://www.genome.jp/dbget-bin/www_bget?R00943 R00943]
−
{{#set: reconstruction category=annotation|orthology}}
+
* UNIPROT:
−
{{#set: reconstruction tool=pathwaytools|pantograph}}
+
** [http://www.uniprot.org/uniprot/P09440 P09440]
 +
** [http://www.uniprot.org/uniprot/P13419 P13419]
 +
** [http://www.uniprot.org/uniprot/P07245 P07245]
 +
** [http://www.uniprot.org/uniprot/P11586 P11586]
 +
** [http://www.uniprot.org/uniprot/P21164 P21164]
 +
** [http://www.uniprot.org/uniprot/P28723 P28723]
 +
** [http://www.uniprot.org/uniprot/Q9JVY8 Q9JVY8]
 +
** [http://www.uniprot.org/uniprot/Q9CH07 Q9CH07]
 +
** [http://www.uniprot.org/uniprot/Q07064 Q07064]
 +
** [http://www.uniprot.org/uniprot/Q27772 Q27772]
 +
{{#set: direction=reversible}}
 +
{{#set: common-name=formate:tetrahydropteroylpolyglutamate ligase|formate-tetrahydrofolate ligase}}
 +
{{#set: ec-number=ec-6.3.4.3}}
 +
{{#set: nb gene associated=2}}
 +
{{#set: nb pathway associated=5}}
 +
{{#set: reconstruction category=orthology|annotation}}
 +
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
{{#set: reconstruction comment=n.a}}
 
{{#set: reconstruction comment=n.a}}
−
{{#set: reconstruction source=saccharina_japonica_genome|output_pantograph_ectocarpus_siliculosus}}
+
{{#set: reconstruction source=output_pantograph_ectocarpus_siliculosus|saccharina_japonica_genome}}

Latest revision as of 11:19, 18 March 2021

Reaction FORMATETHFLIG-RXN

  • direction:
    • reversible
  • common-name:
    • formate:tetrahydropteroylpolyglutamate ligase
    • formate-tetrahydrofolate ligase
  • ec-number:

Reaction formula

Gene(s) associated with this reaction

Pathway(s)

  • PWY-2161, folate polyglutamylation:
    • 5 reactions found over 5 reactions in the full pathway
  • PWY-2201, folate transformations I:
    • 9 reactions found over 10 reactions in the full pathway
  • PWY-1722, formate assimilation into 5,10-methylenetetrahydrofolate:
    • 3 reactions found over 3 reactions in the full pathway
  • CODH-PWY, reductive acetyl coenzyme A pathway I (homoacetogenic bacteria):
    • 4 reactions found over 10 reactions in the full pathway
  • PWY-3841, folate transformations II (plants):
    • 9 reactions found over 11 reactions in the full pathway

Reconstruction information

External links





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