GART-RXN

Reaction 2-ISOPROPYLMALATESYN-RXN

• direction:
  • left-to-right
• common-name:
  • 2-isopropylmalate synthase
• ec-number:
  • ec-2.3.3.13

Reaction formula

• 1 2-KETO-ISOVALERATE[c] + 1 ACETYL-COA[c] + 1 WATER[c] => 1 3-CARBOXY-3-HYDROXY-ISOCAPROATE[c] + 1 CO-A[c] + 1 PROTON[c]

Gene(s) associated with this reaction

• Gene: SJ04717
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: ec-number, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_nannochloropsis_salina, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_arabidopsis_thaliana, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a

Pathway(s)

• LEUSYN-PWY, L-leucine biosynthesis: LEUSYN-PWY
  • 5 reactions found over 6 reactions in the full pathway
• PWY-6871, 3-methylbutanol biosynthesis (engineered): PWY-6871
  • 5 reactions found over 7 reactions in the full pathway

Reconstruction information

• category: orthology; source: output_pantograph_arabidopsis_thaliana; tool: pantograph; comment: n.a
• category: orthology; source: output_pantograph_nannochloropsis_salina; tool: pantograph; comment: n.a
• category: orthology; source: output_pantograph_ectocarpus_siliculosus; tool: pantograph; comment: n.a
• category: annotation; source: saccharina_japonica_genome; tool: pathwaytools; comment: n.a

External links

• RHEA:
  • 21525
• LIGAND-RXN:
  • R01213
• UNIPROT:
  • P06208
  • Q58595
  • P09151
  • Q9PLV9
  • Q9JUK6
  • Q58787
  • P94565
  • Q9JP75
  • Q02141
  • P48575
  • O86511