Difference between revisions of "HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN"

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(Created page with "Category:reaction == Reaction ADENOSYLHOMOCYSTEINASE-RXN == * direction: ** reversible * common-name: ** s-adenosylhomocysteine hydrolase * ec-number: ** [http://enzyme.ex...")
(Created page with "Category:reaction == Reaction HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN == * direction: ** reversible * common-name: ** hydroxymethyl glutaryl-coa synthase * ec-number: ** [h...")
 
(6 intermediate revisions by 3 users not shown)
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[[Category:reaction]]
 
[[Category:reaction]]
−
== Reaction ADENOSYLHOMOCYSTEINASE-RXN ==
+
== Reaction HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN ==
 
* direction:
 
* direction:
 
** reversible
 
** reversible
 
* common-name:
 
* common-name:
−
** s-adenosylhomocysteine hydrolase
+
** hydroxymethyl glutaryl-coa synthase
 
* ec-number:
 
* ec-number:
−
** [http://enzyme.expasy.org/EC/3.3.1.1 ec-3.3.1.1]
+
** [http://enzyme.expasy.org/EC/2.3.3.10 ec-2.3.3.10]
 
== Reaction formula ==
 
== Reaction formula ==
−
* 1 [[ADENOSYL-HOMO-CYS]][c] '''+''' 1 [[WATER]][c] '''<=>''' 1 [[ADENOSINE]][c] '''+''' 1 [[HOMO-CYS]][c]
+
* 1 [[ACETOACETYL-COA]][c] '''+''' 1 [[ACETYL-COA]][c] '''+''' 1 [[WATER]][c] '''<=>''' 1 [[3-HYDROXY-3-METHYL-GLUTARYL-COA]][c] '''+''' 1 [[CO-A]][c] '''+''' 1 [[PROTON]][c]
 
== Gene(s) associated with this reaction  ==
 
== Gene(s) associated with this reaction  ==
−
* Gene: [[SJ07466]]
+
* Gene: [[SJ06617]]
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
** Category: [[orthology]]
 
** Category: [[orthology]]
−
*** Source: [[output_pantograph_nannochloropsis_salina]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
 
*** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
*** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 +
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 +
* Gene: [[SJ11593]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 +
** Category: [[orthology]]
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
== Pathway(s)  ==
 
== Pathway(s)  ==
−
* [[METHIONINE-DEG1-PWY]], L-methionine degradation I (to L-homocysteine):
+
* [[PWY-7391]], isoprene biosynthesis II (engineered):
−
** '''2''' reactions found over '''3''' reactions in the full pathway
+
** '''7''' reactions found over '''8''' reactions in the full pathway
−
* [[PWY-5041]], S-adenosyl-L-methionine cycle II:
+
* [[PWY-7524]], mevalonate pathway III (Thermoplasma):
−
** '''3''' reactions found over '''4''' reactions in the full pathway
+
** '''5''' reactions found over '''8''' reactions in the full pathway
 +
* [[PWY-922]], mevalonate pathway I (eukaryotes and bacteria):
 +
** '''7''' reactions found over '''7''' reactions in the full pathway
 +
* [[PWY-6174]], mevalonate pathway II (haloarchaea):
 +
** '''6''' reactions found over '''7''' reactions in the full pathway
 +
* [[PWY66-367]], ketogenesis:
 +
** '''4''' reactions found over '''5''' reactions in the full pathway
 +
* [[PWY-7571]], ferrichrome A biosynthesis:
 +
** '''1''' reactions found over '''5''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
−
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
 
−
* category: [[orthology]]; source: [[output_pantograph_nannochloropsis_salina]]; tool: [[pantograph]]; comment: n.a
 
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 
* category: [[orthology]]; source: [[output_pantograph_arabidopsis_thaliana]]; tool: [[pantograph]]; comment: n.a
 
* category: [[orthology]]; source: [[output_pantograph_arabidopsis_thaliana]]; tool: [[pantograph]]; comment: n.a
 +
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
 
== External links  ==
 
== External links  ==
 
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
 
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
 +
* METANETX-RXN : MNXR107257
 
* RHEA:
 
* RHEA:
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=21711 21711]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=10191 10191]
 
* LIGAND-RXN:
 
* LIGAND-RXN:
−
** [http://www.genome.jp/dbget-bin/www_bget?R00192 R00192]
+
** [http://www.genome.jp/dbget-bin/www_bget?R01978 R01978]
 
* UNIPROT:
 
* UNIPROT:
−
** [http://www.uniprot.org/uniprot/P10760 P10760]
+
** [http://www.uniprot.org/uniprot/P13704 P13704]
−
** [http://www.uniprot.org/uniprot/P10819 P10819]
+
** [http://www.uniprot.org/uniprot/P22791 P22791]
−
** [http://www.uniprot.org/uniprot/P23526 P23526]
+
** [http://www.uniprot.org/uniprot/P54870 P54870]
−
** [http://www.uniprot.org/uniprot/P28183 P28183]
+
** [http://www.uniprot.org/uniprot/P54869 P54869]
−
** [http://www.uniprot.org/uniprot/P50250 P50250]
+
** [http://www.uniprot.org/uniprot/O51626 O51626]
−
** [http://www.uniprot.org/uniprot/P60176 P60176]
+
** [http://www.uniprot.org/uniprot/Q9CFA9 Q9CFA9]
−
** [http://www.uniprot.org/uniprot/Q58783 Q58783]
+
** [http://www.uniprot.org/uniprot/P17425 P17425]
−
** [http://www.uniprot.org/uniprot/O23255 O23255]
+
** [http://www.uniprot.org/uniprot/Q7LZE7 Q7LZE7]
−
** [http://www.uniprot.org/uniprot/O27673 O27673]
+
** [http://www.uniprot.org/uniprot/Q01581 Q01581]
−
** [http://www.uniprot.org/uniprot/O29376 O29376]
+
** [http://www.uniprot.org/uniprot/P54961 P54961]
−
** [http://www.uniprot.org/uniprot/O28279 O28279]
+
** [http://www.uniprot.org/uniprot/P54839 P54839]
−
** [http://www.uniprot.org/uniprot/P51893 P51893]
+
** [http://www.uniprot.org/uniprot/P54874 P54874]
−
** [http://www.uniprot.org/uniprot/P50245 P50245]
+
** [http://www.uniprot.org/uniprot/P54868 P54868]
−
** [http://www.uniprot.org/uniprot/P26799 P26799]
+
** [http://www.uniprot.org/uniprot/P54873 P54873]
−
** [http://www.uniprot.org/uniprot/P35007 P35007]
+
** [http://www.uniprot.org/uniprot/P93773 P93773]
−
** [http://www.uniprot.org/uniprot/P39954 P39954]
 
−
** [http://www.uniprot.org/uniprot/P50252 P50252]
 
−
** [http://www.uniprot.org/uniprot/P50249 P50249]
 
−
** [http://www.uniprot.org/uniprot/P74008 P74008]
 
−
** [http://www.uniprot.org/uniprot/P32112 P32112]
 
−
** [http://www.uniprot.org/uniprot/Q9UG84 Q9UG84]
 
−
** [http://www.uniprot.org/uniprot/Q01781 Q01781]
 
−
** [http://www.uniprot.org/uniprot/P27604 P27604]
 
 
</div>
 
</div>
 
{{#set: direction=reversible}}
 
{{#set: direction=reversible}}
−
{{#set: common-name=s-adenosylhomocysteine hydrolase}}
+
{{#set: common-name=hydroxymethyl glutaryl-coa synthase}}
−
{{#set: ec-number=ec-3.3.1.1}}
+
{{#set: ec-number=ec-2.3.3.10}}
−
{{#set: nb gene associated=1}}
+
{{#set: nb gene associated=2}}
−
{{#set: nb pathway associated=2}}
+
{{#set: nb pathway associated=6}}
−
{{#set: reconstruction category=annotation|orthology}}
+
{{#set: reconstruction category=orthology|annotation}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
{{#set: reconstruction comment=n.a}}
 
{{#set: reconstruction comment=n.a}}
−
{{#set: reconstruction source=saccharina_japonica_genome|output_pantograph_ectocarpus_siliculosus|output_pantograph_nannochloropsis_salina|output_pantograph_arabidopsis_thaliana}}
+
{{#set: reconstruction source=output_pantograph_ectocarpus_siliculosus|output_pantograph_arabidopsis_thaliana|saccharina_japonica_genome}}

Latest revision as of 11:23, 18 March 2021

Reaction HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN

  • direction:
    • reversible
  • common-name:
    • hydroxymethyl glutaryl-coa synthase
  • ec-number:

Reaction formula

Gene(s) associated with this reaction

Pathway(s)

  • PWY-7391, isoprene biosynthesis II (engineered):
    • 7 reactions found over 8 reactions in the full pathway
  • PWY-7524, mevalonate pathway III (Thermoplasma):
    • 5 reactions found over 8 reactions in the full pathway
  • PWY-922, mevalonate pathway I (eukaryotes and bacteria):
    • 7 reactions found over 7 reactions in the full pathway
  • PWY-6174, mevalonate pathway II (haloarchaea):
    • 6 reactions found over 7 reactions in the full pathway
  • PWY66-367, ketogenesis:
    • 4 reactions found over 5 reactions in the full pathway
  • PWY-7571, ferrichrome A biosynthesis:
    • 1 reactions found over 5 reactions in the full pathway

Reconstruction information

External links





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