Difference between revisions of "RXN-10721"

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(Created page with "Category:reaction == Reaction 3-ISOPROPYLMALDEHYDROG-RXN == * direction: ** reversible * common-name: ** 3-isopropylmalate dehydrogenase * synonymous: ** β-isopropylm...")
(Created page with "Category:reaction == Reaction RXN-11662 == * direction: ** reversible * common-name: ** (s)-3-hydroxybutanoyl-coa dehydrogeanse ** 3-hydroxyacyl-coa dehydrogenase * ec-num...")
Line 1: Line 1:
 
[[Category:reaction]]
 
[[Category:reaction]]
−
== Reaction 3-ISOPROPYLMALDEHYDROG-RXN ==
+
== Reaction RXN-11662 ==
 
* direction:
 
* direction:
 
** reversible
 
** reversible
 
* common-name:
 
* common-name:
−
** 3-isopropylmalate dehydrogenase
+
** (s)-3-hydroxybutanoyl-coa dehydrogeanse
−
* synonymous:
+
** 3-hydroxyacyl-coa dehydrogenase
−
** β-isopropylmalic enzyme
+
* ec-number:
−
** threo-ds-3-isopropylmalate dehydrogenase
+
** [http://enzyme.expasy.org/EC/1.1.1.35 ec-1.1.1.35]
 
== Reaction formula ==
 
== Reaction formula ==
−
* 1 [[2-D-THREO-HYDROXY-3-CARBOXY-ISOCAPROATE]][c] '''+''' 1 [[NAD]][c] '''<=>''' 1 [[CPD-7100]][c] '''+''' 1 [[NADH]][c] '''+''' 1 [[PROTON]][c]
+
* 1 [[NAD]][c] '''+''' 1 [[S-3-HYDROXYBUTANOYL-COA]][c] '''<=>''' 1 [[ACETOACETYL-COA]][c] '''+''' 1 [[NADH]][c] '''+''' 1 [[PROTON]][c]
 
== Gene(s) associated with this reaction  ==
 
== Gene(s) associated with this reaction  ==
−
* Gene: [[SJ21291]]
+
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
 +
* Gene: [[SJ21390]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
** Category: [[orthology]]
 +
*** Source: [[output_pantograph_nannochloropsis_salina]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 +
*** Source: [[output_pantograph_nannochloropsis_salina]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 +
* Gene: [[SJ17348]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
* Gene: [[SJ16470]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
* Gene: [[SJ16180]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
* Gene: [[SJ03584]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 +
** Category: [[orthology]]
 +
*** Source: [[output_pantograph_nannochloropsis_salina]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 +
* Gene: [[SJ06127]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
* Gene: [[SJ07211]]
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
Line 17: Line 41:
 
*** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
*** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 +
* Gene: [[SJ01444]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 +
</div>
 
== Pathway(s)  ==
 
== Pathway(s)  ==
−
* [[LEUSYN-PWY]], L-leucine biosynthesis:
+
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
 +
* [[PWY-5177]], glutaryl-CoA degradation:
 +
** '''5''' reactions found over '''5''' reactions in the full pathway
 +
* [[PWY-7778]], 2-methylpropene degradation:
 +
** '''3''' reactions found over '''8''' reactions in the full pathway
 +
* [[PWY-6863]], pyruvate fermentation to hexanol (engineered):
 +
** '''9''' reactions found over '''11''' reactions in the full pathway
 +
* [[CENTFERM-PWY]], pyruvate fermentation to butanoate:
 +
** '''5''' reactions found over '''7''' reactions in the full pathway
 +
* [[PWY-6583]], pyruvate fermentation to butanol I:
 +
** '''6''' reactions found over '''8''' reactions in the full pathway
 +
* [[PWY-6883]], pyruvate fermentation to butanol II (engineered):
 
** '''5''' reactions found over '''6''' reactions in the full pathway
 
** '''5''' reactions found over '''6''' reactions in the full pathway
−
* [[PWY-6871]], 3-methylbutanol biosynthesis (engineered):
+
* [[PWY-5789]], 3-hydroxypropanoate/4-hydroxybutanate cycle:
−
** '''5''' reactions found over '''7''' reactions in the full pathway
+
** '''8''' reactions found over '''18''' reactions in the full pathway
 +
* [[P162-PWY]], L-glutamate degradation V (via hydroxyglutarate):
 +
** '''7''' reactions found over '''11''' reactions in the full pathway
 +
* [[PWY-7216]], (R)- and (S)-3-hydroxybutanoate biosynthesis (engineered):
 +
** '''3''' reactions found over '''5''' reactions in the full pathway
 +
* [[PWY-7401]], crotonate fermentation (to acetate and cyclohexane carboxylate):
 +
** '''6''' reactions found over '''15''' reactions in the full pathway
 +
* [[PWY-7779]], methyl tert-butyl ether degradation:
 +
** '''2''' reactions found over '''10''' reactions in the full pathway
 +
</div>
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 +
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
 +
* category: [[orthology]]; source: [[output_pantograph_nannochloropsis_salina]]; tool: [[pantograph]]; comment: n.a
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
−
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
 
 
* category: [[orthology]]; source: [[output_pantograph_arabidopsis_thaliana]]; tool: [[pantograph]]; comment: n.a
 
* category: [[orthology]]; source: [[output_pantograph_arabidopsis_thaliana]]; tool: [[pantograph]]; comment: n.a
 
== External links  ==
 
== External links  ==
−
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
 
 
* RHEA:
 
* RHEA:
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=10895 10895]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=30802 30802]
 
* LIGAND-RXN:
 
* LIGAND-RXN:
−
** [http://www.genome.jp/dbget-bin/www_bget?R04426 R04426]
+
** [http://www.genome.jp/dbget-bin/www_bget?R01975 R01975]
−
* UNIPROT:
 
−
** [http://www.uniprot.org/uniprot/P05644 P05644]
 
−
** [http://www.uniprot.org/uniprot/P05645 P05645]
 
−
** [http://www.uniprot.org/uniprot/Q01987 Q01987]
 
−
** [http://www.uniprot.org/uniprot/Q00412 Q00412]
 
−
** [http://www.uniprot.org/uniprot/P08791 P08791]
 
−
** [http://www.uniprot.org/uniprot/P30125 P30125]
 
−
** [http://www.uniprot.org/uniprot/Q9PLW0 Q9PLW0]
 
−
** [http://www.uniprot.org/uniprot/O66607 O66607]
 
−
** [http://www.uniprot.org/uniprot/P12010 P12010]
 
−
** [http://www.uniprot.org/uniprot/P04173 P04173]
 
−
** [http://www.uniprot.org/uniprot/Q5SIY4 Q5SIY4]
 
−
** [http://www.uniprot.org/uniprot/P24098 P24098]
 
−
** [http://www.uniprot.org/uniprot/Q9JU79 Q9JU79]
 
−
** [http://www.uniprot.org/uniprot/P43860 P43860]
 
−
** [http://www.uniprot.org/uniprot/P41019 P41019]
 
−
** [http://www.uniprot.org/uniprot/P54354 P54354]
 
−
** [http://www.uniprot.org/uniprot/Q56268 Q56268]
 
−
** [http://www.uniprot.org/uniprot/P29102 P29102]
 
−
** [http://www.uniprot.org/uniprot/P37412 P37412]
 
−
** [http://www.uniprot.org/uniprot/P23390 P23390]
 
−
** [http://www.uniprot.org/uniprot/P29696 P29696]
 
−
** [http://www.uniprot.org/uniprot/P41766 P41766]
 
−
** [http://www.uniprot.org/uniprot/Q02143 Q02143]
 
−
** [http://www.uniprot.org/uniprot/P34733 P34733]
 
−
** [http://www.uniprot.org/uniprot/P50180 P50180]
 
−
** [http://www.uniprot.org/uniprot/Q12591 Q12591]
 
−
** [http://www.uniprot.org/uniprot/Q12590 Q12590]
 
−
** [http://www.uniprot.org/uniprot/Q12592 Q12592]
 
−
** [http://www.uniprot.org/uniprot/P07139 P07139]
 
−
** [http://www.uniprot.org/uniprot/P41926 P41926]
 
−
** [http://www.uniprot.org/uniprot/P48012 P48012]
 
−
** [http://www.uniprot.org/uniprot/P87256 P87256]
 
−
** [http://www.uniprot.org/uniprot/P87257 P87257]
 
−
** [http://www.uniprot.org/uniprot/P73960 P73960]
 
−
** [http://www.uniprot.org/uniprot/O86504 O86504]
 
−
** [http://www.uniprot.org/uniprot/O85837 O85837]
 
−
** [http://www.uniprot.org/uniprot/P18869 P18869]
 
−
** [http://www.uniprot.org/uniprot/P34738 P34738]
 
−
</div>
 
 
{{#set: direction=reversible}}
 
{{#set: direction=reversible}}
−
{{#set: common-name=3-isopropylmalate dehydrogenase}}
+
{{#set: common-name=3-hydroxyacyl-coa dehydrogenase|(s)-3-hydroxybutanoyl-coa dehydrogeanse}}
−
{{#set: synonymous=threo-ds-3-isopropylmalate dehydrogenase|&beta;-isopropylmalic enzyme}}
+
{{#set: ec-number=ec-1.1.1.35}}
−
{{#set: nb gene associated=1}}
+
{{#set: nb gene associated=8}}
−
{{#set: nb pathway associated=2}}
+
{{#set: nb pathway associated=11}}
 
{{#set: reconstruction category=annotation|orthology}}
 
{{#set: reconstruction category=annotation|orthology}}
 
{{#set: reconstruction tool=pathwaytools|pantograph}}
 
{{#set: reconstruction tool=pathwaytools|pantograph}}
 
{{#set: reconstruction comment=n.a}}
 
{{#set: reconstruction comment=n.a}}
−
{{#set: reconstruction source=output_pantograph_arabidopsis_thaliana|saccharina_japonica_genome|output_pantograph_ectocarpus_siliculosus}}
+
{{#set: reconstruction source=output_pantograph_nannochloropsis_salina|output_pantograph_arabidopsis_thaliana|saccharina_japonica_genome|output_pantograph_ectocarpus_siliculosus}}

Revision as of 11:23, 15 January 2021

Reaction RXN-11662

  • direction:
    • reversible
  • common-name:
    • (s)-3-hydroxybutanoyl-coa dehydrogeanse
    • 3-hydroxyacyl-coa dehydrogenase
  • ec-number:

Reaction formula

Gene(s) associated with this reaction

Pathway(s)

  • PWY-5177, glutaryl-CoA degradation:
    • 5 reactions found over 5 reactions in the full pathway
  • PWY-7778, 2-methylpropene degradation:
    • 3 reactions found over 8 reactions in the full pathway
  • PWY-6863, pyruvate fermentation to hexanol (engineered):
    • 9 reactions found over 11 reactions in the full pathway
  • CENTFERM-PWY, pyruvate fermentation to butanoate:
    • 5 reactions found over 7 reactions in the full pathway
  • PWY-6583, pyruvate fermentation to butanol I:
    • 6 reactions found over 8 reactions in the full pathway
  • PWY-6883, pyruvate fermentation to butanol II (engineered):
    • 5 reactions found over 6 reactions in the full pathway
  • PWY-5789, 3-hydroxypropanoate/4-hydroxybutanate cycle:
    • 8 reactions found over 18 reactions in the full pathway
  • P162-PWY, L-glutamate degradation V (via hydroxyglutarate):
    • 7 reactions found over 11 reactions in the full pathway
  • PWY-7216, (R)- and (S)-3-hydroxybutanoate biosynthesis (engineered):
    • 3 reactions found over 5 reactions in the full pathway
  • PWY-7401, crotonate fermentation (to acetate and cyclohexane carboxylate):
    • 6 reactions found over 15 reactions in the full pathway
  • PWY-7779, methyl tert-butyl ether degradation:
    • 2 reactions found over 10 reactions in the full pathway

Reconstruction information

External links





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