Difference between revisions of "RXN-11757"

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(Created page with "Category:reaction == Reaction RXN66-18 == * direction: ** left-to-right * common-name: ** 4α-carboxy-4β-methyl-5α-cholesta-8-en-3β-ol:nad(p)+ 3-oxido...")
(Created page with "Category:reaction == Reaction HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN == * direction: ** reversible * common-name: ** hydroxymethyl glutaryl-coa synthase * ec-number: ** [h...")
Line 1: Line 1:
 
[[Category:reaction]]
 
[[Category:reaction]]
−
== Reaction RXN66-18 ==
+
== Reaction HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN ==
 
* direction:
 
* direction:
−
** left-to-right
+
** reversible
 
* common-name:
 
* common-name:
−
** 4α-carboxy-4β-methyl-5α-cholesta-8-en-3β-ol:nad(p)+ 3-oxidoreductase (decarboxylating)
+
** hydroxymethyl glutaryl-coa synthase
 
* ec-number:
 
* ec-number:
−
** [http://enzyme.expasy.org/EC/1.1.1.170 ec-1.1.1.170]
+
** [http://enzyme.expasy.org/EC/2.3.3.10 ec-2.3.3.10]
 
== Reaction formula ==
 
== Reaction formula ==
−
* 1 [[CPD-8613]][c] '''+''' 1 [[NAD-P-OR-NOP]][c] '''=>''' 1 [[CARBON-DIOXIDE]][c] '''+''' 1 [[CPD-8614]][c] '''+''' 1 [[NADH-P-OR-NOP]][c]
+
* 1 [[ACETOACETYL-COA]][c] '''+''' 1 [[ACETYL-COA]][c] '''+''' 1 [[WATER]][c] '''<=>''' 1 [[3-HYDROXY-3-METHYL-GLUTARYL-COA]][c] '''+''' 1 [[CO-A]][c] '''+''' 1 [[PROTON]][c]
 
== Gene(s) associated with this reaction  ==
 
== Gene(s) associated with this reaction  ==
−
* Gene: [[SJ04782]]
+
* Gene: [[SJ11593]]
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 +
** Category: [[orthology]]
 +
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 +
* Gene: [[SJ06617]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 +
** Category: [[orthology]]
 +
*** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 +
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
== Pathway(s)  ==
 
== Pathway(s)  ==
−
* [[PWY66-3]], cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
+
* [[PWY-922]], mevalonate pathway I:
−
** '''12''' reactions found over '''18''' reactions in the full pathway
+
** '''7''' reactions found over '''7''' reactions in the full pathway
 +
* [[PWY-6174]], mevalonate pathway II (archaea):
 +
** '''6''' reactions found over '''7''' reactions in the full pathway
 +
* [[PWY66-367]], ketogenesis:
 +
** '''4''' reactions found over '''5''' reactions in the full pathway
 +
* [[PWY-7571]], ferrichrome A biosynthesis:
 +
** '''1''' reactions found over '''5''' reactions in the full pathway
 +
* [[PWY-7391]], isoprene biosynthesis II (engineered):
 +
** '''7''' reactions found over '''8''' reactions in the full pathway
 +
* [[PWY-7524]], mevalonate pathway III (archaea):
 +
** '''5''' reactions found over '''8''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 +
* category: [[orthology]]; source: [[output_pantograph_arabidopsis_thaliana]]; tool: [[pantograph]]; comment: n.a
 +
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
 
== External links  ==
 
== External links  ==
−
{{#set: direction=left-to-right}}
+
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
−
{{#set: common-name=4&alpha;-carboxy-4&beta;-methyl-5&alpha;-cholesta-8-en-3&beta;-ol:nad(p)+ 3-oxidoreductase (decarboxylating)}}
+
* RHEA:
−
{{#set: ec-number=ec-1.1.1.170}}
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=10191 10191]
−
{{#set: nb gene associated=1}}
+
* LIGAND-RXN:
−
{{#set: nb pathway associated=1}}
+
** [http://www.genome.jp/dbget-bin/www_bget?R01978 R01978]
−
{{#set: reconstruction category=annotation}}
+
* UNIPROT:
−
{{#set: reconstruction tool=pathwaytools}}
+
** [http://www.uniprot.org/uniprot/P13704 P13704]
 +
** [http://www.uniprot.org/uniprot/P22791 P22791]
 +
** [http://www.uniprot.org/uniprot/P54870 P54870]
 +
** [http://www.uniprot.org/uniprot/P54869 P54869]
 +
** [http://www.uniprot.org/uniprot/O51626 O51626]
 +
** [http://www.uniprot.org/uniprot/Q9CFA9 Q9CFA9]
 +
** [http://www.uniprot.org/uniprot/P17425 P17425]
 +
** [http://www.uniprot.org/uniprot/Q7LZE7 Q7LZE7]
 +
** [http://www.uniprot.org/uniprot/Q01581 Q01581]
 +
** [http://www.uniprot.org/uniprot/P54961 P54961]
 +
** [http://www.uniprot.org/uniprot/P54839 P54839]
 +
** [http://www.uniprot.org/uniprot/P54874 P54874]
 +
** [http://www.uniprot.org/uniprot/P54868 P54868]
 +
** [http://www.uniprot.org/uniprot/P54873 P54873]
 +
** [http://www.uniprot.org/uniprot/P93773 P93773]
 +
</div>
 +
{{#set: direction=reversible}}
 +
{{#set: common-name=hydroxymethyl glutaryl-coa synthase}}
 +
{{#set: ec-number=ec-2.3.3.10}}
 +
{{#set: nb gene associated=2}}
 +
{{#set: nb pathway associated=6}}
 +
{{#set: reconstruction category=annotation|orthology}}
 +
{{#set: reconstruction tool=pathwaytools|pantograph}}
 
{{#set: reconstruction comment=n.a}}
 
{{#set: reconstruction comment=n.a}}
−
{{#set: reconstruction source=saccharina_japonica_genome}}
+
{{#set: reconstruction source=output_pantograph_arabidopsis_thaliana|saccharina_japonica_genome|output_pantograph_ectocarpus_siliculosus}}

Revision as of 15:06, 5 January 2021

Reaction HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN

  • direction:
    • reversible
  • common-name:
    • hydroxymethyl glutaryl-coa synthase
  • ec-number:

Reaction formula

Gene(s) associated with this reaction

Pathway(s)

  • PWY-922, mevalonate pathway I:
    • 7 reactions found over 7 reactions in the full pathway
  • PWY-6174, mevalonate pathway II (archaea):
    • 6 reactions found over 7 reactions in the full pathway
  • PWY66-367, ketogenesis:
    • 4 reactions found over 5 reactions in the full pathway
  • PWY-7571, ferrichrome A biosynthesis:
    • 1 reactions found over 5 reactions in the full pathway
  • PWY-7391, isoprene biosynthesis II (engineered):
    • 7 reactions found over 8 reactions in the full pathway
  • PWY-7524, mevalonate pathway III (archaea):
    • 5 reactions found over 8 reactions in the full pathway

Reconstruction information

External links





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