Difference between revisions of "RXN-12570"

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(Created page with "Category:reaction == Reaction ACETYL-COA-ACETYLTRANSFER-RXN == * direction: ** reversible * common-name: ** acetyl-coa acetyltransferase * ec-number: ** [http://enzyme.exp...")
(Created page with "Category:reaction == Reaction RXN-12570 == * direction: ** left-to-right * common-name: ** 3-hydroxyhexanoyl-coa dehydrogenase ** 3-hydroxyacyl-coa dehydrogenase * ec-numb...")
 
(6 intermediate revisions by 3 users not shown)
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[[Category:reaction]]
 
[[Category:reaction]]
−
== Reaction ACETYL-COA-ACETYLTRANSFER-RXN ==
+
== Reaction RXN-12570 ==
 
* direction:
 
* direction:
−
** reversible
+
** left-to-right
 
* common-name:
 
* common-name:
−
** acetyl-coa acetyltransferase
+
** 3-hydroxyhexanoyl-coa dehydrogenase
 +
** 3-hydroxyacyl-coa dehydrogenase
 
* ec-number:
 
* ec-number:
−
** [http://enzyme.expasy.org/EC/2.3.1.9 ec-2.3.1.9]
+
** [http://enzyme.expasy.org/EC/1.1.1.35 ec-1.1.1.35]
 
== Reaction formula ==
 
== Reaction formula ==
−
* 2 [[ACETYL-COA]][c] '''<=>''' 1 [[ACETOACETYL-COA]][c] '''+''' 1 [[CO-A]][c]
+
* 1 [[K-HEXANOYL-COA]][c] '''+''' 1 [[NADH]][c] '''+''' 1 [[PROTON]][c] '''=>''' 1 [[NAD]][c] '''+''' 1 [[OH-HEXANOYL-COA]][c]
 
== Gene(s) associated with this reaction  ==
 
== Gene(s) associated with this reaction  ==
−
* Gene: [[SJ09371]]
+
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
 +
* Gene: [[SJ01444]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 +
* Gene: [[SJ16180]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
* Gene: [[SJ21390]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
** Category: [[orthology]]
 
** Category: [[orthology]]
−
*** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
+
*** Source: [[output_pantograph_nannochloropsis_salina]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
−
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
+
*** Source: [[output_pantograph_nannochloropsis_salina]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
−
* Gene: [[SJ14898]]
+
* Gene: [[SJ03584]]
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
** Category: [[orthology]]
 
** Category: [[orthology]]
 
*** Source: [[output_pantograph_nannochloropsis_salina]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
*** Source: [[output_pantograph_nannochloropsis_salina]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
−
*** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
+
*** Source: [[output_pantograph_nannochloropsis_salina]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
−
*** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
+
* Gene: [[SJ17348]]
−
*** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
+
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
* Gene: [[SJ07211]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 +
** Category: [[orthology]]
 
*** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
*** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
−
* Gene: [[SJ21818]]
+
* Gene: [[SJ16470]]
−
** Category: [[orthology]]
+
** Category: [[annotation]]
−
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
+
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
* Gene: [[SJ06127]]
 +
** Category: [[annotation]]
 +
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 +
</div>
 
== Pathway(s)  ==
 
== Pathway(s)  ==
−
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
 
−
* [[PWY-6174]], mevalonate pathway II (archaea):
 
−
** '''6''' reactions found over '''7''' reactions in the full pathway
 
−
* [[PWY-6883]], pyruvate fermentation to butanol II (engineered):
 
−
** '''5''' reactions found over '''6''' reactions in the full pathway
 
−
* [[PWY-6876]], isopropanol biosynthesis (engineered):
 
−
** '''2''' reactions found over '''5''' reactions in the full pathway
 
−
* [[ACETOACETATE-DEG-PWY]], acetoacetate degradation (to acetyl CoA):
 
−
** '''1''' reactions found over '''2''' reactions in the full pathway
 
−
* [[PWY-5177]], glutaryl-CoA degradation:
 
−
** '''5''' reactions found over '''5''' reactions in the full pathway
 
−
* [[PWY-6588]], pyruvate fermentation to acetone:
 
−
** '''2''' reactions found over '''5''' reactions in the full pathway
 
−
* [[PWY-922]], mevalonate pathway I:
 
−
** '''7''' reactions found over '''7''' reactions in the full pathway
 
−
* [[PWY-6583]], pyruvate fermentation to butanol I:
 
−
** '''6''' reactions found over '''8''' reactions in the full pathway
 
−
* [[PWY-5789]], 3-hydroxypropanoate/4-hydroxybutanate cycle:
 
−
** '''8''' reactions found over '''18''' reactions in the full pathway
 
−
* [[PWY1-3]], polyhydroxybutanoate biosynthesis:
 
−
** '''2''' reactions found over '''3''' reactions in the full pathway
 
−
* [[PWY-7216]], (R)- and (S)-3-hydroxybutanoate biosynthesis (engineered):
 
−
** '''3''' reactions found over '''5''' reactions in the full pathway
 
−
* [[PWY-7401]], crotonate fermentation (to acetate and cyclohexane carboxylate):
 
−
** '''6''' reactions found over '''15''' reactions in the full pathway
 
−
* [[PWY-7391]], isoprene biosynthesis II (engineered):
 
−
** '''7''' reactions found over '''8''' reactions in the full pathway
 
−
* [[P162-PWY]], L-glutamate degradation V (via hydroxyglutarate):
 
−
** '''7''' reactions found over '''11''' reactions in the full pathway
 
−
* [[PWY-5741]], ethylmalonyl-CoA pathway:
 
−
** '''2''' reactions found over '''11''' reactions in the full pathway
 
 
* [[PWY-6863]], pyruvate fermentation to hexanol (engineered):
 
* [[PWY-6863]], pyruvate fermentation to hexanol (engineered):
 
** '''9''' reactions found over '''11''' reactions in the full pathway
 
** '''9''' reactions found over '''11''' reactions in the full pathway
−
* [[P163-PWY]], L-lysine fermentation to acetate and butanoate:
 
−
** '''3''' reactions found over '''10''' reactions in the full pathway
 
−
* [[PWY-7779]], methyl tert-butyl ether degradation:
 
−
** '''2''' reactions found over '''10''' reactions in the full pathway
 
−
* [[PWY-7778]], 2-methylpropene degradation:
 
−
** '''3''' reactions found over '''8''' reactions in the full pathway
 
−
* [[PWY-7524]], mevalonate pathway III (archaea):
 
−
** '''5''' reactions found over '''8''' reactions in the full pathway
 
−
* [[PWY66-368]], ketolysis:
 
−
** '''2''' reactions found over '''3''' reactions in the full pathway
 
−
* [[PWY66-367]], ketogenesis:
 
−
** '''4''' reactions found over '''5''' reactions in the full pathway
 
−
* [[PWY-5676]], acetyl-CoA fermentation to butanoate II:
 
−
** '''4''' reactions found over '''5''' reactions in the full pathway
 
−
* [[CENTFERM-PWY]], pyruvate fermentation to butanoate:
 
−
** '''5''' reactions found over '''7''' reactions in the full pathway
 
−
</div>
 
 
== Reconstruction information  ==
 
== Reconstruction information  ==
−
* category: [[orthology]]; source: [[output_pantograph_arabidopsis_thaliana]]; tool: [[pantograph]]; comment: n.a
 
 
* category: [[orthology]]; source: [[output_pantograph_nannochloropsis_salina]]; tool: [[pantograph]]; comment: n.a
 
* category: [[orthology]]; source: [[output_pantograph_nannochloropsis_salina]]; tool: [[pantograph]]; comment: n.a
 +
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
 
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
−
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
+
* category: [[orthology]]; source: [[output_pantograph_arabidopsis_thaliana]]; tool: [[pantograph]]; comment: n.a
 
== External links  ==
 
== External links  ==
−
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
+
* METANETX-RXN : MNXR100543
 
* RHEA:
 
* RHEA:
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=21039 21039]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=31144 31144]
 
* LIGAND-RXN:
 
* LIGAND-RXN:
−
** [http://www.genome.jp/dbget-bin/www_bget?R00238 R00238]
+
** [http://www.genome.jp/dbget-bin/www_bget?R04748 R04748]
−
* UNIPROT:
+
{{#set: direction=left-to-right}}
−
** [http://www.uniprot.org/uniprot/Q8CAY6 Q8CAY6]
+
{{#set: common-name=3-hydroxyhexanoyl-coa dehydrogenase|3-hydroxyacyl-coa dehydrogenase}}
−
** [http://www.uniprot.org/uniprot/P41338 P41338]
+
{{#set: ec-number=ec-1.1.1.35}}
−
** [http://www.uniprot.org/uniprot/P45362 P45362]
+
{{#set: nb gene associated=8}}
−
** [http://www.uniprot.org/uniprot/Q9BWD1 Q9BWD1]
+
{{#set: nb pathway associated=1}}
−
** [http://www.uniprot.org/uniprot/P45359 P45359]
+
{{#set: reconstruction category=orthology|annotation}}
−
** [http://www.uniprot.org/uniprot/P24752 P24752]
+
{{#set: reconstruction tool=pathwaytools|pantograph}}
−
** [http://www.uniprot.org/uniprot/Q12598 Q12598]
 
−
** [http://www.uniprot.org/uniprot/P45369 P45369]
 
−
** [http://www.uniprot.org/uniprot/P46707 P46707]
 
−
** [http://www.uniprot.org/uniprot/P73825 P73825]
 
−
** [http://www.uniprot.org/uniprot/Q43637 Q43637]
 
−
** [http://www.uniprot.org/uniprot/Q9UQW6 Q9UQW6]
 
−
** [http://www.uniprot.org/uniprot/Q9Z3Y4 Q9Z3Y4]
 
−
** [http://www.uniprot.org/uniprot/P77852 P77852]
 
−
** [http://www.uniprot.org/uniprot/Q9XD81 Q9XD81]
 
−
** [http://www.uniprot.org/uniprot/Q9ZGI9 Q9ZGI9]
 
−
** [http://www.uniprot.org/uniprot/Q9L8E0 Q9L8E0]
 
−
** [http://www.uniprot.org/uniprot/P14611 P14611]
 
−
** [http://www.uniprot.org/uniprot/P07097 P07097]
 
−
** [http://www.uniprot.org/uniprot/P17764 P17764]
 
−
</div>
 
−
{{#set: direction=reversible}}
 
−
{{#set: common-name=acetyl-coa acetyltransferase}}
 
−
{{#set: ec-number=ec-2.3.1.9}}
 
−
{{#set: nb gene associated=3}}
 
−
{{#set: nb pathway associated=24}}
 
−
{{#set: reconstruction category=annotation|orthology}}
 
−
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
 
{{#set: reconstruction comment=n.a}}
 
{{#set: reconstruction comment=n.a}}
−
{{#set: reconstruction source=saccharina_japonica_genome|output_pantograph_ectocarpus_siliculosus|output_pantograph_nannochloropsis_salina|output_pantograph_arabidopsis_thaliana}}
+
{{#set: reconstruction source=output_pantograph_nannochloropsis_salina|output_pantograph_ectocarpus_siliculosus|output_pantograph_arabidopsis_thaliana|saccharina_japonica_genome}}

Latest revision as of 11:19, 18 March 2021

Reaction RXN-12570

  • direction:
    • left-to-right
  • common-name:
    • 3-hydroxyhexanoyl-coa dehydrogenase
    • 3-hydroxyacyl-coa dehydrogenase
  • ec-number:

Reaction formula

Gene(s) associated with this reaction

Pathway(s)

  • PWY-6863, pyruvate fermentation to hexanol (engineered):
    • 9 reactions found over 11 reactions in the full pathway

Reconstruction information

External links

  • METANETX-RXN : MNXR100543
  • RHEA:
  • LIGAND-RXN:





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