RXN-8364

Reaction RXN-11662

• direction:
  • reversible
• common-name:
  • (s)-3-hydroxybutanoyl-coa dehydrogeanse
  • 3-hydroxyacyl-coa dehydrogenase
• ec-number:
  • ec-1.1.1.35

Reaction formula

• 1 NAD[c] + 1 S-3-HYDROXYBUTANOYL-COA[c] <=> 1 ACETOACETYL-COA[c] + 1 NADH[c] + 1 PROTON[c]

Gene(s) associated with this reaction

• Gene: SJ21390
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_nannochloropsis_salina, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_nannochloropsis_salina, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: SJ17348
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: SJ16470
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: SJ16180
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: SJ03584
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: ec-number, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_nannochloropsis_salina, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: SJ06127
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: SJ07211
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: ec-number, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_arabidopsis_thaliana, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: SJ01444
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: ec-number, Comment: n.a

Pathway(s)

• PWY-5177, glutaryl-CoA degradation: PWY-5177
  • 5 reactions found over 5 reactions in the full pathway
• PWY-7778, 2-methylpropene degradation: PWY-7778
  • 3 reactions found over 8 reactions in the full pathway
• PWY-6863, pyruvate fermentation to hexanol (engineered): PWY-6863
  • 9 reactions found over 11 reactions in the full pathway
• CENTFERM-PWY, pyruvate fermentation to butanoate: CENTFERM-PWY
  • 5 reactions found over 7 reactions in the full pathway
• PWY-6583, pyruvate fermentation to butanol I: PWY-6583
  • 6 reactions found over 8 reactions in the full pathway
• PWY-6883, pyruvate fermentation to butanol II (engineered): PWY-6883
  • 5 reactions found over 6 reactions in the full pathway
• PWY-5789, 3-hydroxypropanoate/4-hydroxybutanate cycle: PWY-5789
  • 8 reactions found over 18 reactions in the full pathway
• P162-PWY, L-glutamate degradation V (via hydroxyglutarate): P162-PWY
  • 7 reactions found over 11 reactions in the full pathway
• PWY-7216, (R)- and (S)-3-hydroxybutanoate biosynthesis (engineered): PWY-7216
  • 3 reactions found over 5 reactions in the full pathway
• PWY-7401, crotonate fermentation (to acetate and cyclohexane carboxylate): PWY-7401
  • 6 reactions found over 15 reactions in the full pathway
• PWY-7779, methyl tert-butyl ether degradation: PWY-7779
  • 2 reactions found over 10 reactions in the full pathway

Reconstruction information

• category: orthology; source: output_pantograph_ectocarpus_siliculosus; tool: pantograph; comment: n.a
• category: orthology; source: output_pantograph_nannochloropsis_salina; tool: pantograph; comment: n.a
• category: annotation; source: saccharina_japonica_genome; tool: pathwaytools; comment: n.a
• category: orthology; source: output_pantograph_arabidopsis_thaliana; tool: pantograph; comment: n.a

External links

• RHEA:
  • 30802
• LIGAND-RXN:
  • R01975