Difference between revisions of "RXN-8991"

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(Created page with "Category:reaction == Reaction RXN-17795 == * direction: ** left-to-right * common-name: ** acetyl-coa c-acyltransferase ** 3-ketoacyl-coa thiolase * ec-number: ** [http://...")
(Created page with "Category:reaction == Reaction RXN-8991 == * direction: ** reversible * common-name: ** 3-isopropylmalate dehydratase ** (2r,3s)-3-isopropylmalate hydro-lyase (2-isopropylm...")
 
Line 1: Line 1:
 
[[Category:reaction]]
 
[[Category:reaction]]
−
== Reaction RXN-17795 ==
+
== Reaction RXN-8991 ==
 
* direction:
 
* direction:
−
** left-to-right
+
** reversible
 
* common-name:
 
* common-name:
−
** acetyl-coa c-acyltransferase
+
** 3-isopropylmalate dehydratase
−
** 3-ketoacyl-coa thiolase
+
** (2r,3s)-3-isopropylmalate hydro-lyase (2-isopropylmaleate-forming)
−
* ec-number:
+
* synonymous:
−
** [http://enzyme.expasy.org/EC/2.3.1.16 ec-2.3.1.16]
+
** α-isopropylmalate isomerase
 +
** 3-isopropylmalate hydro-lyase
 +
** (2r,3s)-3-isopropylmalate hydro-lyase
 +
** β-isopropylmalate dehydratase
 
== Reaction formula ==
 
== Reaction formula ==
−
* 1 [[CO-A]][c] '''+''' 1 [[CPD-19157]][c] '''=>''' 1 [[ACETYL-COA]][c] '''+''' 1 [[CPD-19148]][c]
+
* 1 [[2-D-THREO-HYDROXY-3-CARBOXY-ISOCAPROATE]][c] '''<=>''' 1 [[CPD-9451]][c] '''+''' 1 [[WATER]][c]
 
== Gene(s) associated with this reaction  ==
 
== Gene(s) associated with this reaction  ==
−
* Gene: [[SJ21818]]
+
* Gene: [[SJ22396]]
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
−
* Gene: [[SJ14898]]
+
** Category: [[orthology]]
−
** Category: [[annotation]]
+
*** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
+
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
−
* Gene: [[SJ21817]]
+
* Gene: [[SJ09771]]
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
−
* Gene: [[SJ16470]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
−
* Gene: [[SJ09371]]
 
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 +
** Category: [[orthology]]
 +
*** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 +
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
== Pathway(s)  ==
 
== Pathway(s)  ==
 +
* [[PWY-6871]], 3-methylbutanol biosynthesis (engineered):
 +
** '''5''' reactions found over '''7''' reactions in the full pathway
 +
* [[LEUSYN-PWY]], L-leucine biosynthesis:
 +
** '''5''' reactions found over '''6''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 +
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 +
* category: [[orthology]]; source: [[output_pantograph_arabidopsis_thaliana]]; tool: [[pantograph]]; comment: n.a
 
== External links  ==
 
== External links  ==
−
* METANETX-RXN : MNXR121170
+
* METANETX-RXN : MNXR100827
−
{{#set: direction=left-to-right}}
+
* RHEA:
−
{{#set: common-name=acetyl-coa c-acyltransferase|3-ketoacyl-coa thiolase}}
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=10676 10676]
−
{{#set: ec-number=ec-2.3.1.16}}
+
* LIGAND-RXN:
−
{{#set: nb gene associated=5}}
+
** [http://www.genome.jp/dbget-bin/www_bget?R04001 R04001]
−
{{#set: nb pathway associated=0}}
+
{{#set: direction=reversible}}
−
{{#set: reconstruction category=annotation}}
+
{{#set: common-name=3-isopropylmalate dehydratase|(2r,3s)-3-isopropylmalate hydro-lyase (2-isopropylmaleate-forming)}}
−
{{#set: reconstruction tool=pathwaytools}}
+
{{#set: synonymous=&alpha;-isopropylmalate isomerase|3-isopropylmalate hydro-lyase|&beta;-isopropylmalate dehydratase|(2r,3s)-3-isopropylmalate hydro-lyase}}
 +
{{#set: nb gene associated=2}}
 +
{{#set: nb pathway associated=2}}
 +
{{#set: reconstruction category=orthology|annotation}}
 +
{{#set: reconstruction tool=pathwaytools|pantograph}}
 
{{#set: reconstruction comment=n.a}}
 
{{#set: reconstruction comment=n.a}}
−
{{#set: reconstruction source=saccharina_japonica_genome}}
+
{{#set: reconstruction source=output_pantograph_ectocarpus_siliculosus|output_pantograph_arabidopsis_thaliana|saccharina_japonica_genome}}

Latest revision as of 11:22, 18 March 2021

Reaction RXN-8991

  • direction:
    • reversible
  • common-name:
    • 3-isopropylmalate dehydratase
    • (2r,3s)-3-isopropylmalate hydro-lyase (2-isopropylmaleate-forming)
  • synonymous:
    • α-isopropylmalate isomerase
    • 3-isopropylmalate hydro-lyase
    • (2r,3s)-3-isopropylmalate hydro-lyase
    • β-isopropylmalate dehydratase

Reaction formula

Gene(s) associated with this reaction

Pathway(s)

  • PWY-6871, 3-methylbutanol biosynthesis (engineered):
    • 5 reactions found over 7 reactions in the full pathway
  • LEUSYN-PWY, L-leucine biosynthesis:
    • 5 reactions found over 6 reactions in the full pathway

Reconstruction information

External links

  • METANETX-RXN : MNXR100827
  • RHEA:
  • LIGAND-RXN:





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