RXN-9205

Reaction 3-OXOACYL-ACP-SYNTH-BASE-RXN

• direction:
  • left-to-right
• common-name:
  • fatty acid synthase
• ec-number:
  • ec-2.3.1.179
  • ec-2.3.1.41
  • ec-2.3.1.85
  • ec-2.3.1.86

Reaction formula

• 1 ACETYL-ACP[c] + 1 MALONYL-ACP[c] + 1 PROTON[c] => 1 ACP[c] + 1 Acetoacetyl-ACPs[c] + 1 CARBON-DIOXIDE[c]

Gene(s) associated with this reaction

• Gene: SJ17743
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: SJ15984
  • Category: orthology
    • Source: output_pantograph_nannochloropsis_salina, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: SJ15983
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_arabidopsis_thaliana, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_arabidopsis_thaliana, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: SJ03883
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: SJ06944
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: SJ13014
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: SJ04443
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_nannochloropsis_salina, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_arabidopsis_thaliana, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_arabidopsis_thaliana, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: SJ18059
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: SJ06616
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: SJ19629
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: SJ00613
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: SJ06617
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: SJ00320
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: SJ04769
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: SJ11672
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: SJ00005
  • Category: orthology
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: SJ10624
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a

Pathway(s)

• PWY-7388, octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast):
  • 7 reactions found over 11 reactions in the full pathway
• PWY-5966:
  • 2 reactions found over n.a reactions in the full pathway
• PWY-5965:
  • 1 reactions found over n.a reactions in the full pathway
• FASYN-INITIAL-PWY, superpathway of fatty acid biosynthesis initiation (E. coli):
  • 5 reactions found over 2 reactions in the full pathway

Reconstruction information

• category: orthology; source: output_pantograph_nannochloropsis_salina; tool: pantograph; comment: n.a
• category: orthology; source: output_pantograph_arabidopsis_thaliana; tool: pantograph; comment: n.a
• category: annotation; source: saccharina_japonica_genome; tool: pathwaytools; comment: n.a
• category: orthology; source: output_pantograph_ectocarpus_siliculosus; tool: pantograph; comment: n.a

External links

• LIGAND-RXN:
  • R04355
• METANETX-RXN : MNXR100912
• UNIPROT:
  • P23902
  • P0A6R0
  • P49327
  • P43710
  • Q9HYR2
  • O67612
  • P20582
  • Q9JT63
  • Q9JW56
  • Q9PMZ6
  • P43711
  • O25284
  • Q9JX65
  • O34340
  • Q9PI63
  • P0AAI5
  • Q07510
  • Q06097
  • P41175
  • P31176
  • Q40027
  • Q40028
  • P73283
  • P0A953
  • O64485
  • O65677
  • Q39310
  • O23738
  • Q41134
  • Q41135
  • Q54208
  • O54440
  • P55338
  • Q9RA31
  • P12276
  • P12785