Difference between revisions of "RXN66-12"

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(Created page with "Category:reaction == Reaction 3-CH3-2-OXOBUTANOATE-OH-CH3-XFER-RXN == * direction: ** reversible * common-name: ** 3-methyl-2-oxobutanoate hydroxymethyltransferase * ec-nu...")
(Created page with "Category:reaction == Reaction RXN66-12 == * direction: ** left-to-right * common-name: ** 4,4-dimethyl-14α-hydroxymethyl-5α-cholesta-8-en-3β-ol 14-dehydro...")
 
(2 intermediate revisions by 2 users not shown)
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[[Category:reaction]]
 
[[Category:reaction]]
−
== Reaction 3-CH3-2-OXOBUTANOATE-OH-CH3-XFER-RXN ==
+
== Reaction RXN66-12 ==
 
* direction:
 
* direction:
−
** reversible
+
** left-to-right
 
* common-name:
 
* common-name:
−
** 3-methyl-2-oxobutanoate hydroxymethyltransferase
+
** 4,4-dimethyl-14α-hydroxymethyl-5α-cholesta-8-en-3β-ol 14-dehydrogenase
−
* ec-number:
+
** 4,4-dimethyl-14α-hydroxymethyl-5α-cholesta-8-en-3β-ol,nadph:oxygen oxidoreductase
−
** [http://enzyme.expasy.org/EC/2.1.2.11 ec-2.1.2.11]
 
 
== Reaction formula ==
 
== Reaction formula ==
−
* 1 [[2-KETO-ISOVALERATE]][c] '''+''' 1 [[METHYLENE-THF-GLU-N]][c] '''+''' 1 [[WATER]][c] '''<=>''' 1 [[2-DEHYDROPANTOATE]][c] '''+''' 1 [[THF-GLU-N]][c]
+
* 1 [[CPD-8607]][c] '''+''' 1 [[NADPH]][c] '''+''' 1 [[OXYGEN-MOLECULE]][c] '''+''' 1 [[PROTON]][c] '''=>''' 1 [[CPD-8608]][c] '''+''' 1 [[NADP]][c] '''+''' 2 [[WATER]][c]
 
== Gene(s) associated with this reaction  ==
 
== Gene(s) associated with this reaction  ==
−
* Gene: [[SJ10361]]
+
* Gene: [[SJ05072]]
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
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*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
== Pathway(s)  ==
 
== Pathway(s)  ==
−
* [[PANTO-PWY]], phosphopantothenate biosynthesis I:
+
* [[PWY66-3]], cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
−
** '''4''' reactions found over '''4''' reactions in the full pathway
+
** '''12''' reactions found over '''18''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 +
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
 
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
−
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 
 
== External links  ==
 
== External links  ==
−
* RHEA:
+
* METANETX-RXN : MNXR144151
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=11827 11827]
+
{{#set: direction=left-to-right}}
−
* LIGAND-RXN:
+
{{#set: common-name=4,4-dimethyl-14&alpha;-hydroxymethyl-5&alpha;-cholesta-8-en-3&beta;-ol 14-dehydrogenase|4,4-dimethyl-14&alpha;-hydroxymethyl-5&alpha;-cholesta-8-en-3&beta;-ol,nadph:oxygen oxidoreductase}}
−
** [http://www.genome.jp/dbget-bin/www_bget?R01226 R01226]
 
−
* UNIPROT:
 
−
** [http://www.uniprot.org/uniprot/Q9V0E1 Q9V0E1]
 
−
** [http://www.uniprot.org/uniprot/Q9JUY0 Q9JUY0]
 
−
** [http://www.uniprot.org/uniprot/P31057 P31057]
 
−
** [http://www.uniprot.org/uniprot/Q9PIK1 Q9PIK1]
 
−
** [http://www.uniprot.org/uniprot/P38122 P38122]
 
−
** [http://www.uniprot.org/uniprot/Q09672 Q09672]
 
−
** [http://www.uniprot.org/uniprot/P52997 P52997]
 
−
** [http://www.uniprot.org/uniprot/Q9X712 Q9X712]
 
−
** [http://www.uniprot.org/uniprot/Q9Y7B6 Q9Y7B6]
 
−
** [http://www.uniprot.org/uniprot/Q9L7B2 Q9L7B2]
 
−
** [http://www.uniprot.org/uniprot/Q9RKS2 Q9RKS2]
 
−
** [http://www.uniprot.org/uniprot/Q9RLE2 Q9RLE2]
 
−
{{#set: direction=reversible}}
 
−
{{#set: common-name=3-methyl-2-oxobutanoate hydroxymethyltransferase}}
 
−
{{#set: ec-number=ec-2.1.2.11}}
 
 
{{#set: nb gene associated=1}}
 
{{#set: nb gene associated=1}}
 
{{#set: nb pathway associated=1}}
 
{{#set: nb pathway associated=1}}
−
{{#set: reconstruction category=annotation|orthology}}
+
{{#set: reconstruction category=orthology|annotation}}
−
{{#set: reconstruction tool=pathwaytools|pantograph}}
+
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
{{#set: reconstruction comment=n.a}}
 
{{#set: reconstruction comment=n.a}}
−
{{#set: reconstruction source=saccharina_japonica_genome|output_pantograph_ectocarpus_siliculosus}}
+
{{#set: reconstruction source=output_pantograph_ectocarpus_siliculosus|saccharina_japonica_genome}}

Latest revision as of 11:22, 18 March 2021

Reaction RXN66-12

  • direction:
    • left-to-right
  • common-name:
    • 4,4-dimethyl-14α-hydroxymethyl-5α-cholesta-8-en-3β-ol 14-dehydrogenase
    • 4,4-dimethyl-14α-hydroxymethyl-5α-cholesta-8-en-3β-ol,nadph:oxygen oxidoreductase

Reaction formula

Gene(s) associated with this reaction

Pathway(s)

  • PWY66-3, cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
    • 12 reactions found over 18 reactions in the full pathway

Reconstruction information

External links

  • METANETX-RXN : MNXR144151





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