Difference between revisions of "RXN66-12"

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(Created page with "Category:reaction == Reaction 3-HYDROXYDECANOYL-ACP-DEHYDR-RXN == * direction: ** left-to-right * common-name: ** fatty acid synthase ** 3-hydroxyacyl-[acp] dehydratase *...")
(Created page with "Category:reaction == Reaction RXN66-12 == * direction: ** left-to-right * common-name: ** 4,4-dimethyl-14α-hydroxymethyl-5α-cholesta-8-en-3β-ol 14-dehydro...")
 
(6 intermediate revisions by 2 users not shown)
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[[Category:reaction]]
 
[[Category:reaction]]
−
== Reaction 3-HYDROXYDECANOYL-ACP-DEHYDR-RXN ==
+
== Reaction RXN66-12 ==
 
* direction:
 
* direction:
 
** left-to-right
 
** left-to-right
 
* common-name:
 
* common-name:
−
** fatty acid synthase
+
** 4,4-dimethyl-14α-hydroxymethyl-5α-cholesta-8-en-3β-ol 14-dehydrogenase
−
** 3-hydroxyacyl-[acp] dehydratase
+
** 4,4-dimethyl-14α-hydroxymethyl-5α-cholesta-8-en-3β-ol,nadph:oxygen oxidoreductase
−
* ec-number:
 
−
** [http://enzyme.expasy.org/EC/2.3.1.86 ec-2.3.1.86]
 
−
** [http://enzyme.expasy.org/EC/2.3.1.85 ec-2.3.1.85]
 
−
** [http://enzyme.expasy.org/EC/4.2.1.59 ec-4.2.1.59]
 
 
== Reaction formula ==
 
== Reaction formula ==
−
* 1 [[OH-ACYL-ACP]][c] '''=>''' 1 [[TRANS-D2-ENOYL-ACP]][c] '''+''' 1 [[WATER]][c]
+
* 1 [[CPD-8607]][c] '''+''' 1 [[NADPH]][c] '''+''' 1 [[OXYGEN-MOLECULE]][c] '''+''' 1 [[PROTON]][c] '''=>''' 1 [[CPD-8608]][c] '''+''' 1 [[NADP]][c] '''+''' 2 [[WATER]][c]
 
== Gene(s) associated with this reaction  ==
 
== Gene(s) associated with this reaction  ==
−
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
+
* Gene: [[SJ05072]]
−
* Gene: [[SJ10624]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ10275]]
 
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
−
* Gene: [[SJ04769]]
+
** Category: [[orthology]]
−
** Category: [[annotation]]
+
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ00320]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ03883]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ06617]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ00613]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ18059]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ06616]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ17743]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ04443]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ13014]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ19629]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ11672]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ06944]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ15983]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
</div>
 
 
== Pathway(s)  ==
 
== Pathway(s)  ==
−
* [[FASYN-ELONG-PWY]], fatty acid elongation -- saturated:
+
* [[PWY66-3]], cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
−
** '''5''' reactions found over '''5''' reactions in the full pathway
+
** '''12''' reactions found over '''18''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 +
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
 
== External links  ==
 
== External links  ==
−
* RHEA:
+
* METANETX-RXN : MNXR144151
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=13098 13098]
 
−
* LIGAND-RXN:
 
−
** [http://www.genome.jp/dbget-bin/www_bget?R10208 R10208]
 
−
* UNIPROT:
 
−
** [http://www.uniprot.org/uniprot/P0A6Q3 P0A6Q3]
 
−
** [http://www.uniprot.org/uniprot/P45159 P45159]
 
 
{{#set: direction=left-to-right}}
 
{{#set: direction=left-to-right}}
−
{{#set: common-name=fatty acid synthase|3-hydroxyacyl-[acp] dehydratase}}
+
{{#set: common-name=4,4-dimethyl-14&alpha;-hydroxymethyl-5&alpha;-cholesta-8-en-3&beta;-ol 14-dehydrogenase|4,4-dimethyl-14&alpha;-hydroxymethyl-5&alpha;-cholesta-8-en-3&beta;-ol,nadph:oxygen oxidoreductase}}
−
{{#set: ec-number=ec-2.3.1.86|ec-2.3.1.85|ec-4.2.1.59}}
+
{{#set: nb gene associated=1}}
−
{{#set: nb gene associated=16}}
 
 
{{#set: nb pathway associated=1}}
 
{{#set: nb pathway associated=1}}
−
{{#set: reconstruction category=annotation}}
+
{{#set: reconstruction category=orthology|annotation}}
−
{{#set: reconstruction tool=pathwaytools}}
+
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
{{#set: reconstruction comment=n.a}}
 
{{#set: reconstruction comment=n.a}}
−
{{#set: reconstruction source=saccharina_japonica_genome}}
+
{{#set: reconstruction source=output_pantograph_ectocarpus_siliculosus|saccharina_japonica_genome}}

Latest revision as of 11:22, 18 March 2021

Reaction RXN66-12

  • direction:
    • left-to-right
  • common-name:
    • 4,4-dimethyl-14α-hydroxymethyl-5α-cholesta-8-en-3β-ol 14-dehydrogenase
    • 4,4-dimethyl-14α-hydroxymethyl-5α-cholesta-8-en-3β-ol,nadph:oxygen oxidoreductase

Reaction formula

Gene(s) associated with this reaction

Pathway(s)

  • PWY66-3, cholesterol biosynthesis II (via 24,25-dihydrolanosterol):
    • 12 reactions found over 18 reactions in the full pathway

Reconstruction information

External links

  • METANETX-RXN : MNXR144151





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