Difference between revisions of "RXN66-303"

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(Created page with "Category:reaction == Reaction HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN == * direction: ** reversible * common-name: ** hydroxymethyl glutaryl-coa synthase * ec-number: ** [h...")
(Created page with "Category:reaction == Reaction RXN66-303 == * direction: ** left-to-right * common-name: ** lanosterol 14-hydroxylase ** lanosterol,nadph:oxygen oxidoreductase == Reaction...")
 
Line 1: Line 1:
 
[[Category:reaction]]
 
[[Category:reaction]]
−
== Reaction HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN ==
+
== Reaction RXN66-303 ==
 
* direction:
 
* direction:
−
** reversible
+
** left-to-right
 
* common-name:
 
* common-name:
−
** hydroxymethyl glutaryl-coa synthase
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** lanosterol 14-hydroxylase
−
* ec-number:
+
** lanosterol,nadph:oxygen oxidoreductase
−
** [http://enzyme.expasy.org/EC/2.3.3.10 ec-2.3.3.10]
 
 
== Reaction formula ==
 
== Reaction formula ==
−
* 1 [[ACETOACETYL-COA]][c] '''+''' 1 [[ACETYL-COA]][c] '''+''' 1 [[WATER]][c] '''<=>''' 1 [[3-HYDROXY-3-METHYL-GLUTARYL-COA]][c] '''+''' 1 [[CO-A]][c] '''+''' 1 [[PROTON]][c]
+
* 1 [[LANOSTEROL]][c] '''+''' 1 [[NADPH]][c] '''+''' 1 [[OXYGEN-MOLECULE]][c] '''+''' 1 [[PROTON]][c] '''=>''' 1 [[CPD-4568]][c] '''+''' 1 [[NADP]][c] '''+''' 1 [[WATER]][c]
 
== Gene(s) associated with this reaction  ==
 
== Gene(s) associated with this reaction  ==
−
* Gene: [[SJ06617]]
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* Gene: [[SJ05072]]
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
−
** Category: [[orthology]]
 
−
*** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
−
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
−
* Gene: [[SJ11593]]
 
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
Line 22: Line 15:
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
== Pathway(s)  ==
 
== Pathway(s)  ==
−
* [[PWY-7391]], isoprene biosynthesis II (engineered):
+
* [[PWY66-4]], cholesterol biosynthesis III (via desmosterol):
−
** '''7''' reactions found over '''8''' reactions in the full pathway
+
** '''14''' reactions found over '''4''' reactions in the full pathway
−
* [[PWY-7524]], mevalonate pathway III (Thermoplasma):
+
* [[PWY66-341]], cholesterol biosynthesis I:
−
** '''5''' reactions found over '''8''' reactions in the full pathway
+
** '''14''' reactions found over '''18''' reactions in the full pathway
−
* [[PWY-922]], mevalonate pathway I (eukaryotes and bacteria):
 
−
** '''7''' reactions found over '''7''' reactions in the full pathway
 
−
* [[PWY-6174]], mevalonate pathway II (haloarchaea):
 
−
** '''6''' reactions found over '''7''' reactions in the full pathway
 
−
* [[PWY66-367]], ketogenesis:
 
−
** '''4''' reactions found over '''5''' reactions in the full pathway
 
−
* [[PWY-7571]], ferrichrome A biosynthesis:
 
−
** '''1''' reactions found over '''5''' reactions in the full pathway
 
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
−
* category: [[orthology]]; source: [[output_pantograph_arabidopsis_thaliana]]; tool: [[pantograph]]; comment: n.a
 
 
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
 
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
 
== External links  ==
 
== External links  ==
−
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
+
* METANETX-RXN : MNXR123707
−
* METANETX-RXN : MNXR107257
+
{{#set: direction=left-to-right}}
−
* RHEA:
+
{{#set: common-name=lanosterol 14-hydroxylase|lanosterol,nadph:oxygen oxidoreductase}}
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=10191 10191]
+
{{#set: nb gene associated=1}}
−
* LIGAND-RXN:
+
{{#set: nb pathway associated=2}}
−
** [http://www.genome.jp/dbget-bin/www_bget?R01978 R01978]
 
−
* UNIPROT:
 
−
** [http://www.uniprot.org/uniprot/P13704 P13704]
 
−
** [http://www.uniprot.org/uniprot/P22791 P22791]
 
−
** [http://www.uniprot.org/uniprot/P54870 P54870]
 
−
** [http://www.uniprot.org/uniprot/P54869 P54869]
 
−
** [http://www.uniprot.org/uniprot/O51626 O51626]
 
−
** [http://www.uniprot.org/uniprot/Q9CFA9 Q9CFA9]
 
−
** [http://www.uniprot.org/uniprot/P17425 P17425]
 
−
** [http://www.uniprot.org/uniprot/Q7LZE7 Q7LZE7]
 
−
** [http://www.uniprot.org/uniprot/Q01581 Q01581]
 
−
** [http://www.uniprot.org/uniprot/P54961 P54961]
 
−
** [http://www.uniprot.org/uniprot/P54839 P54839]
 
−
** [http://www.uniprot.org/uniprot/P54874 P54874]
 
−
** [http://www.uniprot.org/uniprot/P54868 P54868]
 
−
** [http://www.uniprot.org/uniprot/P54873 P54873]
 
−
** [http://www.uniprot.org/uniprot/P93773 P93773]
 
−
</div>
 
−
{{#set: direction=reversible}}
 
−
{{#set: common-name=hydroxymethyl glutaryl-coa synthase}}
 
−
{{#set: ec-number=ec-2.3.3.10}}
 
−
{{#set: nb gene associated=2}}
 
−
{{#set: nb pathway associated=6}}
 
 
{{#set: reconstruction category=orthology|annotation}}
 
{{#set: reconstruction category=orthology|annotation}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
{{#set: reconstruction comment=n.a}}
 
{{#set: reconstruction comment=n.a}}
−
{{#set: reconstruction source=output_pantograph_arabidopsis_thaliana|output_pantograph_ectocarpus_siliculosus|saccharina_japonica_genome}}
+
{{#set: reconstruction source=output_pantograph_ectocarpus_siliculosus|saccharina_japonica_genome}}

Latest revision as of 11:23, 18 March 2021

Reaction RXN66-303

  • direction:
    • left-to-right
  • common-name:
    • lanosterol 14-hydroxylase
    • lanosterol,nadph:oxygen oxidoreductase

Reaction formula

Gene(s) associated with this reaction

Pathway(s)

  • PWY66-4, cholesterol biosynthesis III (via desmosterol):
    • 14 reactions found over 4 reactions in the full pathway
  • PWY66-341, cholesterol biosynthesis I:
    • 14 reactions found over 18 reactions in the full pathway

Reconstruction information

External links

  • METANETX-RXN : MNXR123707





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