TTP

Reaction PYRUVDEH-RXN

• direction:
  • left-to-right
• common-name:
  • pyruvate dehydrogenase (nad+)
• ec-number:
  • ec-1.2.1

Reaction formula

• 1 CO-A[c] + 1 NAD[c] + 1 PYRUVATE[c] => 1 ACETYL-COA[c] + 1 CARBON-DIOXIDE[c] + 1 NADH[c]

Gene(s) associated with this reaction

• Gene: SJ06474
  • Category: orthology
    • Source: output_pantograph_arabidopsis_thaliana, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_arabidopsis_thaliana, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: SJ10087
  • Category: orthology
    • Source: output_pantograph_arabidopsis_thaliana, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_arabidopsis_thaliana, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: SJ10725
  • Category: orthology
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: SJ00971
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
  • Category: orthology
    • Source: output_pantograph_arabidopsis_thaliana, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_arabidopsis_thaliana, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: SJ01042
  • Category: annotation
    • Source: saccharina_japonica_genome, Tool: pathwaytools, Assignment: go-term, Comment: n.a
• Gene: SJ19470
  • Category: orthology
    • Source: output_pantograph_arabidopsis_thaliana, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: SJ13629
  • Category: orthology
    • Source: output_pantograph_arabidopsis_thaliana, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_arabidopsis_thaliana, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: SJ09312
  • Category: orthology
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a
• Gene: SJ14925
  • Category: orthology
    • Source: output_pantograph_arabidopsis_thaliana, Tool: pantograph, Assignment: n.a, Comment: n.a
    • Source: output_pantograph_ectocarpus_siliculosus, Tool: pantograph, Assignment: n.a, Comment: n.a

Pathway(s)

• PWY-7384, anaerobic energy metabolism (invertebrates, mitochondrial): PWY-7384
  • 6 reactions found over 10 reactions in the full pathway
• GLYCOLYSIS-TCA-GLYOX-BYPASS, superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass: GLYCOLYSIS-TCA-GLYOX-BYPASS
  • 3 reactions found over 1 reactions in the full pathway
• PWY-7218, photosynthetic 3-hydroxybutanoate biosynthesis (engineered): PWY-7218
  • 7 reactions found over 4 reactions in the full pathway
• PWY-5482, pyruvate fermentation to acetate II: PWY-5482
  • 2 reactions found over 3 reactions in the full pathway
• PWY-5537, pyruvate fermentation to acetate V: PWY-5537
  • 2 reactions found over 2 reactions in the full pathway
• PWY-6886, 1-butanol autotrophic biosynthesis (engineered): PWY-6886
  • 8 reactions found over 5 reactions in the full pathway

Reconstruction information

• category: orthology; source: output_pantograph_arabidopsis_thaliana; tool: pantograph; comment: n.a
• category: orthology; source: output_pantograph_ectocarpus_siliculosus; tool: pantograph; comment: n.a
• category: annotation; source: saccharina_japonica_genome; tool: pathwaytools; comment: n.a

External links

• RHEA:
  • 28042
• LIGAND-RXN:
  • R00209