Difference between revisions of "3-ISOPROPYLMALISOM-RXN"

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(Created page with "Category:reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN0-5330 RXN0-5330] == * direction: ** left-to-right * common-name: ** nadh:ubiquinone oxidoreduct...")
(Created page with "Category:reaction == Reaction 3-ISOPROPYLMALISOM-RXN == * direction: ** reversible * common-name: ** 3-isopropylmalate dehydratase ** (2s)-2-isopropylmalate hydro-lyase (2...")
 
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[[Category:reaction]]
 
[[Category:reaction]]
−
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN0-5330 RXN0-5330] ==
+
== Reaction 3-ISOPROPYLMALISOM-RXN ==
 
* direction:
 
* direction:
−
** left-to-right
+
** reversible
 
* common-name:
 
* common-name:
−
** nadh:ubiquinone oxidoreductase
+
** 3-isopropylmalate dehydratase
−
** nadh dehydrogenase (ubiquinone)
+
** (2s)-2-isopropylmalate hydro-lyase (2-isopropylmaleate-forming)
−
* ec-number:
+
* synonymous:
−
** [http://enzyme.expasy.org/EC/1.6.5.9 ec-1.6.5.9]
+
** α-isopropylmalate isomerase
 +
** 3-isopropylmalate hydro-lyase
 +
** (2r,3s)-3-isopropylmalate hydro-lyase
 +
** β-isopropylmalate dehydratase
 
== Reaction formula ==
 
== Reaction formula ==
−
* 1 [[NADH]][c] '''+''' 1 [[PROTON]][c] '''+''' 1 [[Ubiquinones]][c] '''=>''' 1 [[NAD]][c] '''+''' 1 [[Ubiquinols]][c]
+
* 1 [[CPD-9451]][c] '''+''' 1 [[WATER]][c] '''<=>''' 1 [[3-CARBOXY-3-HYDROXY-ISOCAPROATE]][c]
 
== Gene(s) associated with this reaction  ==
 
== Gene(s) associated with this reaction  ==
−
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
+
* Gene: [[SJ22396]]
−
* Gene: [[SJ21895]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
−
* Gene: [[SJ15450]]
 
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
−
* Gene: [[SJ22333]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
 
** Category: [[orthology]]
 
** Category: [[orthology]]
 +
*** Source: [[output_pantograph_nannochloropsis_salina]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 +
*** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
−
* Gene: [[SJ19412]]
+
* Gene: [[SJ09771]]
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ15310]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ10422]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
** Category: [[orthology]]
 
−
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
−
* Gene: [[SJ02471]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ03600]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
−
* Gene: [[SJ21333]]
 
 
** Category: [[annotation]]
 
** Category: [[annotation]]
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
 
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: ec-number, Comment: n.a
−
* Gene: [[SJ14995]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ05715]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ09960]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ16410]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
−
* Gene: [[SJ21017]]
 
−
** Category: [[annotation]]
 
−
*** Source: [[saccharina_japonica_genome]], Tool: [[pathwaytools]], Assignment: go-term, Comment: n.a
 
 
** Category: [[orthology]]
 
** Category: [[orthology]]
 +
*** Source: [[output_pantograph_nannochloropsis_salina]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 +
*** Source: [[output_pantograph_arabidopsis_thaliana]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
 
*** Source: [[output_pantograph_ectocarpus_siliculosus]], Tool: [[pantograph]], Assignment: n.a, Comment: n.a
−
</div>
 
 
== Pathway(s)  ==
 
== Pathway(s)  ==
−
* [[PWY-7279]], aerobic respiration II (cytochrome c) (yeast): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7279 PWY-7279]
+
* [[LEUSYN-PWY]], L-leucine biosynthesis:
−
** '''4''' reactions found over '''4''' reactions in the full pathway
+
** '''5''' reactions found over '''6''' reactions in the full pathway
−
* [[PWY0-1573]], nitrate reduction VIIIb (dissimilatory): [http://metacyc.org/META/NEW-IMAGE?object=PWY0-1573 PWY0-1573]
+
* [[PWY-6871]], 3-methylbutanol biosynthesis (engineered):
−
** '''1''' reactions found over '''2''' reactions in the full pathway
+
** '''5''' reactions found over '''7''' reactions in the full pathway
−
* [[PWY-7269]], NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7269 PWY-7269]
 
−
** '''5''' reactions found over '''5''' reactions in the full pathway
 
−
* [[PWY0-1568]], NADH to cytochrome bd oxidase electron transfer II: [http://metacyc.org/META/NEW-IMAGE?object=PWY0-1568 PWY0-1568]
 
−
** '''1''' reactions found over '''2''' reactions in the full pathway
 
−
* [[PWY0-1567]], NADH to cytochrome bo oxidase electron transfer II: [http://metacyc.org/META/NEW-IMAGE?object=PWY0-1567 PWY0-1567]
 
−
** '''1''' reactions found over '''2''' reactions in the full pathway
 
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 +
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
 +
* category: [[orthology]]; source: [[output_pantograph_nannochloropsis_salina]]; tool: [[pantograph]]; comment: n.a
 
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
 
* category: [[orthology]]; source: [[output_pantograph_ectocarpus_siliculosus]]; tool: [[pantograph]]; comment: n.a
−
* category: [[annotation]]; source: [[saccharina_japonica_genome]]; tool: [[pathwaytools]]; comment: n.a
+
* category: [[orthology]]; source: [[output_pantograph_arabidopsis_thaliana]]; tool: [[pantograph]]; comment: n.a
 
== External links  ==
 
== External links  ==
 +
<div class="toccolours mw-collapsible mw-collapsed" style="width:100%; overflow:auto;">
 +
* METANETX-RXN : MNXR100826
 
* RHEA:
 
* RHEA:
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=23153 23153]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=16296 16296]
−
{{#set: direction=left-to-right}}
+
* LIGAND-RXN:
−
{{#set: common-name=nadh dehydrogenase (ubiquinone)|nadh:ubiquinone oxidoreductase}}
+
** [http://www.genome.jp/dbget-bin/www_bget?R03968 R03968]
−
{{#set: ec-number=ec-1.6.5.9}}
+
* UNIPROT:
−
{{#set: nb gene associated=14}}
+
** [http://www.uniprot.org/uniprot/Q9PLW1 Q9PLW1]
−
{{#set: nb pathway associated=5}}
+
** [http://www.uniprot.org/uniprot/Q9JU82 Q9JU82]
 +
** [http://www.uniprot.org/uniprot/P80858 P80858]
 +
** [http://www.uniprot.org/uniprot/Q9UZ07 Q9UZ07]
 +
** [http://www.uniprot.org/uniprot/Q9JU81 Q9JU81]
 +
** [http://www.uniprot.org/uniprot/Q58673 Q58673]
 +
** [http://www.uniprot.org/uniprot/Q02144 Q02144]
 +
** [http://www.uniprot.org/uniprot/P44968 P44968]
 +
** [http://www.uniprot.org/uniprot/Q58667 Q58667]
 +
** [http://www.uniprot.org/uniprot/P44438 P44438]
 +
** [http://www.uniprot.org/uniprot/P0A6A6 P0A6A6]
 +
** [http://www.uniprot.org/uniprot/Q9PLW2 Q9PLW2]
 +
** [http://www.uniprot.org/uniprot/Q44022 Q44022]
 +
** [http://www.uniprot.org/uniprot/Q44023 Q44023]
 +
** [http://www.uniprot.org/uniprot/Q44427 Q44427]
 +
** [http://www.uniprot.org/uniprot/P17279 P17279]
 +
** [http://www.uniprot.org/uniprot/P04787 P04787]
 +
** [http://www.uniprot.org/uniprot/P15717 P15717]
 +
** [http://www.uniprot.org/uniprot/P18250 P18250]
 +
** [http://www.uniprot.org/uniprot/Q02142 Q02142]
 +
** [http://www.uniprot.org/uniprot/P30126 P30126]
 +
** [http://www.uniprot.org/uniprot/P50181 P50181]
 +
** [http://www.uniprot.org/uniprot/P07264 P07264]
 +
** [http://www.uniprot.org/uniprot/P74207 P74207]
 +
** [http://www.uniprot.org/uniprot/O86534 O86534]
 +
** [http://www.uniprot.org/uniprot/O86535 O86535]
 +
</div>
 +
{{#set: direction=reversible}}
 +
{{#set: common-name=3-isopropylmalate dehydratase|(2s)-2-isopropylmalate hydro-lyase (2-isopropylmaleate-forming)}}
 +
{{#set: synonymous=&alpha;-isopropylmalate isomerase|3-isopropylmalate hydro-lyase|&beta;-isopropylmalate dehydratase|(2r,3s)-3-isopropylmalate hydro-lyase}}
 +
{{#set: nb gene associated=2}}
 +
{{#set: nb pathway associated=2}}
 
{{#set: reconstruction category=orthology|annotation}}
 
{{#set: reconstruction category=orthology|annotation}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
{{#set: reconstruction comment=n.a}}
 
{{#set: reconstruction comment=n.a}}
−
{{#set: reconstruction source=saccharina_japonica_genome|output_pantograph_ectocarpus_siliculosus}}
+
{{#set: reconstruction source=output_pantograph_nannochloropsis_salina|output_pantograph_ectocarpus_siliculosus|output_pantograph_arabidopsis_thaliana|saccharina_japonica_genome}}

Latest revision as of 11:21, 18 March 2021

Reaction 3-ISOPROPYLMALISOM-RXN

  • direction:
    • reversible
  • common-name:
    • 3-isopropylmalate dehydratase
    • (2s)-2-isopropylmalate hydro-lyase (2-isopropylmaleate-forming)
  • synonymous:
    • α-isopropylmalate isomerase
    • 3-isopropylmalate hydro-lyase
    • (2r,3s)-3-isopropylmalate hydro-lyase
    • β-isopropylmalate dehydratase

Reaction formula

Gene(s) associated with this reaction

Pathway(s)

  • LEUSYN-PWY, L-leucine biosynthesis:
    • 5 reactions found over 6 reactions in the full pathway
  • PWY-6871, 3-methylbutanol biosynthesis (engineered):
    • 5 reactions found over 7 reactions in the full pathway

Reconstruction information

External links





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